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Amy Strom @dnamystrom.bsky.social · 19/06/2026

30% of our proteome is disordered, yet we still don't have reliable ways to predict functional implications of mutations in disordered regions, or drug them. Here's the latest on chromatin, condensates, and cancer from my group in Discovery Onc at Genentech journals.biologists.com/jcs/article/...

journals.biologists.com

Decoding intrinsically disordered regions in chromatin dysfunction and cancer

Summary: This Perspective describes cancer variants that rewire chromatin regulation through intrinsically disordered regions (IDRs) and argues for comprehensive mapping of condensate-related nuclear ...

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Amy Strom @dnamystrom.bsky.social · 22/01/2026

I'm hiring a summer intern! Pursuing a PhD and interested in industry experience? Apply at the link below by Jan 26 to spend 12 weeks onsite at South San Francisco with Genentech's Discovery Oncology department in May-July 2026 pursuing novel therapies targeting disordered protein regions.

roche.wd3.myworkdayjobs.com

2026 Summer Intern - Discovery Oncology

2026 Summer Intern - Discovery Oncology Department Summary The Department of Discovery Oncology is seeking a talented and motivated summer intern to join the biology research efforts to identify and c...

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Amy Strom @dnamystrom.bsky.social · 05/08/2025

First day at my new job! I'm a Lab Head, Principal Scientist in Discovery Oncology at Genentech. I'll be searching for new targets to develop cancer treatments. 2nd photo is my newest friend on campus, decoy-ote. @genentech.bsky.social

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Amy Strom @dnamystrom.bsky.social · 13/07/2025

The latest in my favorite love triangle: Chromatin <-(💜)-> Condensates <-(💚)-> Mechanics

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Amy Strom @dnamystrom.bsky.social · 10/07/2025

Cancelling grants that were already competitively won and awarded is the waste and abuse. www.nytimes.com/2025/07/10/u...

nytimes.com

The Surprising Scientists Hit by Trump’s D.E.I. Cuts

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Amy Strom @dnamystrom.bsky.social · 07/07/2025

I'm thrilled to announce my next career step-- I’m joining Genentech as a Principal Scientist & Lab Head in Discovery Oncology! I’ll be hunting new ways to target cancers using my background in disordered nuclear proteins.

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Amy Strom @dnamystrom.bsky.social · 16/06/2025

If heterochromatin is really a liquid-like condensate, why is it not spherical? We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments www.biorxiv.org/content/10.1...

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