Mechanisms aimed at recovering from heat-induced damage are closely associated with the organism's ability to survive extreme temperature exposure. In such a scenario, we show that autophagy, as a cytoprotective mechanism, ensures recovery and viability after induced heat stress in <i>Saccharomyces</i> …

Macroautophagy/autophagy is a conserved process among eukaryotes and is essential to maintain cell homeostasis; the dysregulation of autophagy has been linked with multiple human diseases, includin...

Metur et al. uncover functions for RNA-binding proteins, Npl3 and Pub1, as key regulators of ATG1 mRNA translation and autophagy during nutrient starvation. They show that Npl3 and Pub1 coordinate to ...