B-Raf Proto-Oncogene ( BRAF ) fusions are rare in melanomas. We present a case of cutaneous melanoma with a Ring Finger Protein 11 ( RNF11 ) ::BRAF fusion in a 63-year-old man with a history of stage IB melanoma on the right upper back (pT2apN0cM0; nonulcerated with a Breslow thickness of 1.2 mm). D …

Dr. Timothy McCalmont co-authors a significant textbook on dermatopathology, enhancing education for both trainees and seasoned professionals in the field.

Nature Communications, Published online: 27 May 2025; doi:10.1038/s41467-025-60014-xMachine learning models represent an opportunity for the automatic generation of histopathology reports. Here, the authors develop HistoGPT, a vision language model that can generate reports from multiple gigapixel-sized whole slide images and also predict tumour thickness, subtypes, and margins, among other diseases.

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In a groundbreaking development at the intersection of artificial intelligence and medical diagnostics, researchers have unveiled a novel AI-driven system named HistoGPT, designed to revolutionize the generation of dermatopathology reports from gigapixel whole slide images (WSIs). The research, recently published in Nature Communications, introduces a cutting-edge deep learning framework that processes the immense and intricate data inherent in gigapixel WSIs, automating and enhancing the precision of dermatopathological assessments.