Sign in

Denis Chaimow

@denischaimow.bsky.social
68 followers 66 following 11 posts
PostsRepliesMedia
Reposted by Denis Chaimow
Romy Lorenz @romy-lorenz.bsky.social · 21/08/2026
Please share widely! 🚀 I am recruiting a PhD student for an exciting cross-species collaborative project using layer fMRI to investigate how interoception shapes cognitive control - Application deadline is: 1.10.2026 - Start: Jan 2027 www.mpg.de/26934670/phd...
mpg.de
PhD Position (m/f/d) | Ultra-High-Field Layer fMRI of Cognitive Control and Interoception
PhD Position in Ultra-High-Field Layer fMRI of Cognitive Control and Interoception
17064
Reposted by Denis Chaimow
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/08/2025
Vascular draining confounds laminar decoding in fMRI www.biorxiv.org/content/10.1101/202…
0138
Reposted by Denis Chaimow
Romy Lorenz @romy-lorenz.bsky.social · 30/08/2025
What started as a journal club on layer decoding turned into a project thanks to @karolisdegutis.bsky.social. Our preprint challenges a widespread assumption in the field: MVPA is not immune to vascular confounds in laminar GE-BOLD decoding, as shown using a mechanistic laminar response model.
0113
Reposted by Denis Chaimow
Karolis Degutis @karolisdegutis.bsky.social · 30/08/2025
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
1198
Reposted by Denis Chaimow
danielhaenelt.bsky.social @danielhaenelt.bsky.social · 01/08/2025
I’m happy to share that our manuscript on the cortical depth-dependency of the GE- and SE-BOLD point spread function at 7 Tesla is now available on bioRxiv! www.biorxiv.org/content/10.1...
biorxiv.org
Spatial specificity of the functional gradient echo and spin echo BOLD signal across cortical depth at 7 T
Functional magnetic resonance imaging (fMRI) at high magnetic field strengths (≥ 7 T) is a promising technique to study the functioning of the human brain at the spatial scale of cortical columns and ...
1127
Reposted by Denis Chaimow
Karolis Degutis @karolisdegutis.bsky.social · 25/06/2025
Very happy to share our work on the neural dynamics of visual working memory maintenance during sensory distraction; now out as a VOR on eLIife: elifesciences.org/articles/99290
elifesciences.org
Neural dynamics of visual working memory representation during sensory distraction
Dynamic shifts in neural coding combined with stable population subspaces enable visual areas to concurrently represent sensory inputs and working memory without mutual interference.
131
Reposted by Denis Chaimow
Imaging Neuroscience @imagingneurosci.bsky.social · 17/03/2025
New paper in Imaging Neuroscience by Fakhereh Movahedian Attar, Nikolaus Weiskopf, et al: Short association fibres form topographic sheets in the human V1–V2 processing stream doi.org/10.1162/imag...
0187
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
I’d like to thank everyone involved in the project! @romy-lorenz.bsky.social, @karolisdegutis.bsky.social, Daniel Haenelt, Robert Trampel, @nikweiskopf.bsky.social
020
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
We argue that our results are biologically plausible, considering both previous research and methodological aspects of layer fMRI acquisition and analysis. Consequently, the functional role of human dlPFC layers, especially deep layers, in working memory remains uncertain.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
Using confidence interval estimation and a series of control analyses, we show that the failure to replicate was likely not an issue of low sensitivity, data quality or methodological choices, such as automatic segmentation and ROI selection.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
We replicated the superficial layer involvement in working memory manipulation but found no evidence for deep layer-specific activation during motor response. Instead, we observed activation across both layers.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
We used a fully automated, pre-registered analysis pipeline, that included automatic ROI definition by combining anatomical information (HCP MMP 1.0 atlas) with functional activation.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
A seminal layer fMRI study (Finn et al. 2019) demonstrated that dlPFC layers were active during the manipulation of working memory items, whereas deeper layers were more engaged during motor responses. www.nature.com/articles/s41... @esfinn.bsky.social
nature.com
Layer-dependent activity in human prefrontal cortex during working memory - Nature Neuroscience
By developing layer-specific functional MRI techniques for a high-order cognitive brain area, Finn et al. dissociate activity in superficial and deeper cortical layers during different periods of a wo...
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
Excited to share our latest preprint: "Challenges in replicating layer-specificity of working memory processes in the human prefrontal cortex.”, where we attempted to replicate layer-specific fMRI findings in the human dlPFC during a working memory task. www.biorxiv.org/content/10.1...
biorxiv.org
Challenges in replicating layer-specificity of working memory processes in human dlPFC
Although working memory reliably activates the dorsolateral prefrontal cortex (dlPFC), the functional significance of its distinct cytoarchitectonic layers is not well understood in humans. A recent f...
174
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
I’d like to thank everyone involved in the project! @romy-lorenz.bsky.social, @karolisdegutis.bsky.social, Daniel Haenelt, Robert Trampel and @nikweiskopf.bsky.social
000
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
We argue that our results are biologically plausible, considering both previous research and methodological aspects of layer fMRI acquisition and analysis. Consequently, the functional role of human dlPFC layers, especially deep layers, in working memory remains uncertain.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
Using confidence interval estimation and a series of control analyses, we show that the failure to replicate was likely not an issue of low sensitivity, data quality or methodological choices, such as automatic segmentation and ROI selection.
100
Denis Chaimow @denischaimow.bsky.social · 20/02/2025
We replicated the superficial layer involvement in working memory manipulation but found no evidence for deep layer-specific activation during motor response. Instead, we observed activation across both layers.
100
Reposted by Denis Chaimow
bioRxivpreprint @biorxivpreprint.bsky.social · 04/02/2025
Challenges in replicating layer-specificity of working memory processes in human dlPFC www.biorxiv.org/content/10.1101/202…
011