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Del Valle Lab at ND @delvallelab.bsky.social · 11/08/2025

Ever wondered how intra-strand staples impact beta-sheet stability? Check out our @J_A_C_S paper on an easy method to promote peptide folding and amyloid seeding activity. Congrats to Abha and Isaac!! pubs.acs.org/doi/10.1021/...

pubs.acs.org

Intrastrand Peptide Staples That Promote β-Sheet Folding, Self-Assembly, and Amyloid Seeding

Side chain stapling of cysteine (Cys) residues offers convenient entry into constrained peptides with enhanced bioactivity and bioavailability. Despite its widespread application in the constraint of ...

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