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David Fischer

@davidsebfischer.bsky.social

1.2K followers 1.1K following 24 posts

I develop mechanistic machine learning tools for single-cell and spatial omics data to understand the regulatory patterns underlying human disease dynamics. ai4biomedicine.org

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David Fischer @davidsebfischer.bsky.social · 26/11/2025

We compared kai with one-shot analysis generation by LLMs by scoring the generated Jupyter notebooks based on various criteria. kai consistently outperforms one-shot analysis generation.

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David Fischer @davidsebfischer.bsky.social · 26/11/2025

kai interacts with human scientists through a chat interface in VS Code and directly edits and executes Jupyter notebooks. This design enables kai to autonomously perform analyses while maintaining full accountability.

A an example chat interaction between kai and the user.

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David Fischer @davidsebfischer.bsky.social · 26/11/2025

This motivated us to build kai: an agentic AI that uses Jupyter notebooks – the same interface that humans use to collaborate.

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David Fischer @davidsebfischer.bsky.social · 26/11/2025

Agentic AI systems are becoming available for use in science – but can we trust them?

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