David Lynn @davidjlynn.bsky.social · 17/04/2026Thanks to the US FDA Division of Bacterial, Parasitic, and Allergenic Products for the invitation to speak and thanks to to the National Health and Medical Research Council, Women's & Children's Hospital Foundation and Flinders Foundation for ongoing support for our work in this area. 000
David Lynn @davidjlynn.bsky.social · 17/04/2026 I'm looking forward to presenting tonight to colleages in the U.S. Food and Drug Administration Office of Vaccines Review and Research on our ongoing work to understand how disruption of the microbiota in early life leads to impaired vaccine immunogenicity. 100
David Lynn @davidjlynn.bsky.social · 23/11/2025Thanks to ABC news for featuring our work today. www.abc.net.au/news/health/...abc.net.auGut bacteria may explain why antibiotics make vaccines less effectiveIt has long been a mystery why antibiotics reduces the effectiveness of some vaccines, but researchers believe bacteria in the gut may play a pivotal role. 000
David Lynn @davidjlynn.bsky.social · 12/09/2025I'm looking forward to speaking at this exciting conference next year. If you're interested in the latest in microbiome research please check it out. 120
David Lynn @davidjlynn.bsky.social · 29/04/2025 www.the-scientist.com/early-life-a...the-scientist.comEarly Life Antibiotics Put Vaccine Response at RiskWhile antibiotics given in the first week of life reduce vaccine responses at 15 months, probiotics might counteract these effects. 011
David Lynn @davidjlynn.bsky.social · 25/04/2025Thanks @natrevimmunol.bsky.social for highlighting our recent @nature.com paper! @flindersuniversity.bsky.social @sahmri.bsky.social 082
David Lynn @davidjlynn.bsky.social · 03/04/2025Based on these findings we will soon start a randomised controlled trial to determine if a probiotic intervention can boost vaccine responses in infants that received antibiotics in the neonatal period. Funded by @WCHFoundation 000
David Lynn @davidjlynn.bsky.social · 03/04/2025Very grateful to all our collaborators especially @HelenSMarshall and her team, the infants and their parents who participated in our study, our facilities incl @SA_genomics and the @sahmri.bsky.social germ-free and flow facilities and our funders @nhmrc.bsky.social and the WCH Foundation 100
David Lynn @davidjlynn.bsky.social · 03/04/2025Neonates who received antibiotics had significantly lower antibody titres to multiple different vaccine antigens especially polysaccharides in the PCV13 vaccine. 100
David Lynn @davidjlynn.bsky.social · 03/04/2025Our paper out today in @nature.com shows the important role Bifidobacteria in the infant gut microbiota play in mediating optimal responses to vaccination. 1103