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David Lynn

@davidjlynn.bsky.social
84 followers 110 following 10 posts

Professor and Group Leader at SAHMRI and Flinders University. Scientific Director SA Genomics Centre. Research interests in systems immunology; host-microbe interactions; genomics, cancer systems biology.

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David Lynn @davidjlynn.bsky.social · 17/04/2026
Thanks to the US FDA Division of Bacterial, Parasitic, and Allergenic Products for the invitation to speak and thanks to to the National Health and Medical Research Council, Women's & Children's Hospital Foundation and Flinders Foundation for ongoing support for our work in this area.
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David Lynn @davidjlynn.bsky.social · 17/04/2026
I'm looking forward to presenting tonight to colleages in the U.S. Food and Drug Administration Office of Vaccines Review and Research on our ongoing work to understand how disruption of the microbiota in early life leads to impaired vaccine immunogenicity.
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David Lynn @davidjlynn.bsky.social · 23/11/2025
Thanks to ABC news for featuring our work today. www.abc.net.au/news/health/...
abc.net.au
Gut bacteria may explain why antibiotics make vaccines less effective
It has long been a mystery why antibiotics reduces the effectiveness of some vaccines, but researchers believe bacteria in the gut may play a pivotal role.
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David Lynn @davidjlynn.bsky.social · 12/09/2025
I'm looking forward to speaking at this exciting conference next year. If you're interested in the latest in microbiome research please check it out.
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David Lynn @davidjlynn.bsky.social · 29/04/2025
www.the-scientist.com/early-life-a...
the-scientist.com
Early Life Antibiotics Put Vaccine Response at Risk
While antibiotics given in the first week of life reduce vaccine responses at 15 months, probiotics might counteract these effects.
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David Lynn @davidjlynn.bsky.social · 25/04/2025
Thanks @natrevimmunol.bsky.social for highlighting our recent @nature.com paper! @flindersuniversity.bsky.social @sahmri.bsky.social
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David Lynn @davidjlynn.bsky.social · 03/04/2025
Based on these findings we will soon start a randomised controlled trial to determine if a probiotic intervention can boost vaccine responses in infants that received antibiotics in the neonatal period. Funded by @WCHFoundation
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David Lynn @davidjlynn.bsky.social · 03/04/2025
Very grateful to all our collaborators especially @HelenSMarshall and her team, the infants and their parents who participated in our study, our facilities incl @SA_genomics and the @sahmri.bsky.social germ-free and flow facilities and our funders @nhmrc.bsky.social and the WCH Foundation
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David Lynn @davidjlynn.bsky.social · 03/04/2025
Neonates who received antibiotics had significantly lower antibody titres to multiple different vaccine antigens especially polysaccharides in the PCV13 vaccine.
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David Lynn @davidjlynn.bsky.social · 03/04/2025
Our paper out today in @nature.com shows the important role Bifidobacteria in the infant gut microbiota play in mediating optimal responses to vaccination.
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