Reposted by @davidcowburn.bsky.social
Years of work, finally out! Nuclear Pore Complexes (NPCs) are the gateways to the nucleus, but how can they be both rapid and picky, even for very large cargoes? To answer this question, we built the most detailed data-driven model to date of transport through NPCs. /
www.pnas.org/doi/10.1073/...
pnas.org
Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport | PNAS
Nuclear pore complexes (NPCs) enable rapid, selective, and robust nucleocytoplasmic
transport. To explain how transport emerges from the system com...