Imad Damaj @damajlab.bsky.social · 03/01/2026Our latest paper on Aromatase inhibitors induce pain-like musculoskeletal symptoms bpspubs.onlinelibrary.wiley.com/doi/10.1111/...bpspubs.onlinelibrary.wiley.com 031
Imad Damaj @damajlab.bsky.social · 27/07/2025www.genengnews.com/topics/trans...genengnews.comWhy We Still Need Animal Research in a World of AI and OrganoidsThe portrayal of uncaring scientists without any thought for the animals being used in their research is far from the truth. 000
Imad Damaj @damajlab.bsky.social · 26/07/2025Just out in @TheJournal_Pain: “Paclitaxel-Induced Neuroinflammation After Systemic Administration in Male and Female Mice” Paclitaxel-induced increase in neuroinflammation is time-, sex-, and tissue- dependent. www.jpain.org/article/S152...jpain.orgPaclitaxel-Induced Neuroinflammation After Systemic Administration in Male and Female MicePeripheral neuropathy is one of the most prevalent neurotoxic, dose-limiting side effects of paclitaxel, a chemotherapy agent used widely in solid cancers. The mechanism of paclitaxel-induced peripher... 020
Imad Damaj @damajlab.bsky.social · 30/03/2025Check out our newest paper with the talented former Ph.D. Student Bryan McKiver! Astrocyte elevated gene-1 (AEG-1) in myeloid cells is a key driver for the development of chemotherapy-induced peripheral neuropathy. www.sciencedirect.com/science/arti...sciencedirect.comAstrocyte elevated gene-1 (AEG-1) in myeloid cells is a key driver for the development of chemotherapy-induced peripheral neuropathyChemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of chemotherapy treatment, often resulting in the discontinuation of … 120
Imad Damaj @damajlab.bsky.social · 17/03/2025Just out: Our paper in collaboration with Javier Gonzalez-Maeso group demonstrating the long lasting effects of a single dose of psilocybin in mouse models of chronic pain. @jgmaeso.bsky.social www.sciencedirect.com/science/arti...sciencedirect.comIUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic painChronic pain is a debilitating disease with current treatments lacking efficacy and safety, therefore discovery of new treatments is crucial. Initial … 010
Reposted by Imad DamajeLife @elife.bsky.social · 16/03/2025Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity. This ‘fundamental’ study into the effects of #psilocin on human neurons: buff.ly/f7cNemV 0152
Imad Damaj @damajlab.bsky.social · 22/02/2025I was happy to be part of this interesting study with @jgmaeso.bsky.social and his team! “Upregulation of the neuropeptide receptor calcitonin receptor-like in the spinal cord via MLL2 in a mouse model of paclitaxel-induced peripheral neuropathy” journals.sagepub.com/doi/10.1177/...journals.sagepub.comSage Journals: Discover world-class researchSubscription and open access journals from Sage, the world's leading independent academic publisher. 010
Imad Damaj @damajlab.bsky.social · 03/02/2025Glad to have been part of this interesting project! pubs.acs.org/doi/10.1021/...pubs.acs.orgNew PPARα Agonist A190-Loaded Microemulsion for Chemotherapy-Induced Peripheral NeuropathyChemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of anticancer agents with limited effective preventive or therapeutic interventions. Although fenofibrate, a peroxisome proli... 020
Imad Damaj @damajlab.bsky.social · 28/01/2025Still working on nicotinic receptors and pain ! pubmed.ncbi.nlm.nih.gov/39829331/pubmed.ncbi.nlm.nih.govSulfonium Moieties as Ammonium Bioisosteres: Novel Ligands for the Alpha7 Nicotinic Acetylcholine Receptor - PubMedIn the pressing quest of novel treatments for chronic pain, α7 nAChR silent agonists show efficacy as anti-inflammatory modulators and represent a promising strategy. Recent findings reveal that a sul... 051
Imad Damaj @damajlab.bsky.social · 23/01/2025What a circus!!! www.science.org/content/arti...science.orgTrump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiringResearchers facing 030
