Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/09/2026Congratulations to our students and professors who received awards from the Biomedical Graduate Student Association! Jishnu Das was recognized as a Distinguished Mentor of the Year finalist. PhD student Alisa Omelchenko was named the Most Well-Rounded Student of the Year. tinyurl.com/BGSA2026 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/09/2026Mehmet Hocaoglu is a practicing rheumatologist and a student in the Computational Biomedicine and Biotechnology MS program. The CoBB program offered Hocaoglu the opportunity to take classes to support his research interests in the clinic. Read more: tinyurl.com/MehmetCoBBtinyurl.comGraduate student Mehmet Hocaoglu applies computational techniques to clinical research - Department of Computational and Systems BiologyMehmet Hocaoglu is a practicing rheumatologist and a student in the Computational Biomedicine and Biotechnology (CoBB) MS program. 001
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/09/2026PhD student Alisa Omelchenko is making strides in the community as a 2026 Pittsburgh 40 under 40 honoree. Omelchenko and the other selected individuals, all under the age of 40, will be honored at an annual awards event in November. Read more: tinyurl.com/Alisa40Under40tinyurl.comAlisa Omelchenko honored as Pittsburgh 40 Under 40 awardee - Department of Computational and Systems BiologyPhD student Alisa Omelchenko is making strides in the community as a 2026 Pittsburgh 40 under 40 honoree. 001
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/08/2026How can lab techniques be adapted with gravity in mind for use on the International Space Station? Professor Kate Rubins, director of the Trivedi Institute for Space and Global Biomedicine, answer this question in an article recently published in Science. Read the story: tinyurl.com/RubinsISStinyurl.comDreams of making drugs and tissues in space get closer to realityMaturing techniques and cheaper launches fuel microgravity research—and hopes of orbital manufacturing 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 27/08/2026The CPCB 20th Anniversary Research Symposium was held on Aug. 20 and 21 and celebrated two decades of success in PhD training for the CMU-PITT Computational Biology PhD Program. Read more about the event: tinyurl.com/CPCB20th 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/08/2026Congratulations to PhD student Anamarie Martinez-Turak, who has received the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (F31). Learn more: tinyurl.com/MartinezTurak 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/08/2026Today was a day for curiosity and camaraderie! Students, alumni and faculty gathered at The Assembly today for the CPCB 20th Anniversary Research Symposium, which celebrates two decades of excellence in training and discovery for the CMU-PITT Computational Biology PhD Program. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 20/08/2026Assistant Professor Keisuke Ishihara’s lab has released a new preprint that sheds light on the development of human cardioids, which are lab-made miniature heart tissue. Read more about the research: tinyurl.com/IshiharaHearttinyurl.comStudy reveals role of hyaluronic acid in human heart development - Department of Computational and Systems BiologyAssistant Professor Keisuke Ishihara’s lab has released a new preprint that sheds light on the development of human cardioids, which are lab-made miniature heart tissue. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/08/2026Laura Tipton realized that she wanted to ask her own research questions. This led her on a path to earning her PhD in computational biology. The CPCB graduate is now an assistant professor of environmental data science at James Madison University. Read more about Tipton: tinyurl.com/Laura-Tiptontinyurl.comCPCB Alumni Success Story: Laura Tipton - Department of Computational and Systems BiologyLaura Tipton is an assistant professor of environmental data science at James Madison University, where she pursues the research questions of her choice in her biology lab. 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/08/2026The beginning of the fall semester is only a few weeks away! If you are a new student, you may have questions about what to expect for your first year at Pitt. We've created this new student survival guide with important information on campus resources. Read the guide: tinyurl.com/NewStudent26tinyurl.com2026 New Student Survival Guide - Department of Computational and Systems BiologyWe’re sure you have many questions about life at Pitt, so we’ve assembled a list of frequently asked questions to make your transition to campus a little easier. 020
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 06/08/2026New research from Warren van Loggerenberg and Fritz Roth sheds light on the variants that cause APS-1, a rare immunodeficiency disease. They assessed the function of 9,790 of these pathogenic variants in their variant effect map. Read the full research article: tinyurl.com/RothVariantstinyurl.comSystematic and proactive evaluation of AIRE missense variant effectsPathogenic variants in the autoimmune regulator (AIRE) cause autoimmune polyendocrine syndrome type 1 (APS-1), a rare primary immunodeficiency disease… 001
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/07/2026Graduate student Hamid Javanshir has always been passionate about the power of research to improve patients' lives. He has a provisional patent application underway for the cancer drug candidates he designed through his computational research. Read more about his work: tinyurl.com/JavanshirRes... 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 24/07/2026CoBB graduate student Maura O'Malley has had a busy summer filled with preparing for graduation and gaining experience as a research intern at Mass General Brigham in Boston. Read more about Maura in our graduate spotlight: tinyurl.com/MauraCoBBtinyurl.comGraduate Spotlight: Maura O’Malley, MS ‘26 - Department of Computational and Systems BiologyMaura O’Malley is preparing for graduation from the computational Biomedicine and Biotechnology master's degree program while making an impact as a research intern at Mass General Brigham. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/07/2026Congratulations to Assistant Professor Nate Lord, who has been awarded a grant from the National Science Foundation’s Faculty Early Career Development Program (CAREER)! Read more about the CAREER award: tinyurl.com/LordCAREERtinyurl.comNate Lord earns Faculty Early Career Development (CAREER) award from the NSF - Department of Computational and Systems BiologyAssistant Professor Nate Lord has been awarded a grant from the National Science Foundation’s Faculty Early Career Development Program (CAREER). 121
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/07/2026Assistant Professor Shikhar Uttam is among a group of 16 research teams awarded $35 million in funding over three years to study new approaches for prevention, early detection and interception of BRCA-related cancers. Learn more about the award: tinyurl.com/UttamGranttinyurl.comPitt Researchers Among Recipients of $35M for BRCA-Related Cancer Research | School of Medicine | University of PittsburghT. Rinda Soong (left), assistant professor of pathology, and Shikhar Uttam (right), assistant professor of computational and systems biology, both in the School of Medicine, University of Pittsburgh, ... 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/07/2026Meet Avery Mills, a former CompBio Academy student who is interning in the Roth lab this summer! Learn more about Avery and her summer research on variant effect maps. tinyurl.com/AveryMillstinyurl.comMeet the Intern: Avery Mills - Department of Computational and Systems BiologyMeet Avery Mills, a former CompBio Academy student who is interning in the Roth lab this summer! 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 30/06/2026For Associate Professor Jim Faeder, no mountain is too high. 🏔️ This summer, he got out of the lab and onto the trail. Faeder traveled to Peru and hiked to the summit of Machu Picchu. Read more about his incredible trip in this summer story: tinyurl.com/FaederTrek 020
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 29/06/2026Our students are presenting their work across the country! Congratulations to PhD student Anamarie Martinez, who won a travel award to attend the FASEB Dynamics and Encoding in Cell Signaling Conference in Nashville. She presented a poster and delivered a flash talk at the conference. 020
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 23/06/2026Shannon Quinn is driven by solving problems that lead to advances in drug discovery. The graduate of the CMU-PITT Computational Biology PhD Program now works as a senior staff machine learning engineer at Valo Health. Read more about Quinn in our alumni success story: tinyurl.com/ShannonQuinntinyurl.comCPCB Alumni Success Story: Shannon Quinn - Department of Computational and Systems BiologyShannon Quinn is driven by solving complex problems that lead to advances in drug discovery. 020
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 17/06/2026Congratulations to Professor Jianhua Xing, who received a grant from the National Institute of General Medical Sciences! This grant will support Xing’s project on quiescence and senescence. Learn more about the research: tinyurl.com/XingNIGMStinyurl.comJianhua Xing awarded grant from National Institute of General Medical Sciences - Department of Computational and Systems BiologyProfessor Jianhua Xing received an R01 grant from the National Institute of General Medical Sciences (NIGMS). 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/06/2026Spring cleaning isn't just for closets 💻 This month, take 15 minutes to clear out old files in OneDrive and SharePoint. The time you spend helps to reduce Pitt’s carbon footprint. #DigitalSpringCleaning 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/06/2026Check out our new home at Fifth and Halket! 030
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/06/2026Congratulations to Associate Professor John Barton, who has received a Maximizing Investigators’ Research Award from the National Institutes of Health! Read more about the award: tinyurl.com/BartonNIH 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/05/2026Let's unlock curiosity and pursue discovery this summer! Undergraduate students have arrived for the TECBio REU program, a 10-week summer program that provides a challenging and fulfilling graduate-level research experience in computational biology. 110
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 14/05/2026Ericka Mochan always knew she wanted to be a teacher. In our alumni success story, the Chair of the Department of Computational and Chemical Sciences at Carlow University reflects on how earning her computational biology PhD helped her achieve a dream career. tinyurl.com/ErickaMochantinyurl.comCPCB Alumni Success Story: Ericka Mochan - Department of Computational and Systems BiologyMochan is a graduate of the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology (CPCB) and currently serves as the Chair of the Department of Computational and Chemical... 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/05/2026Now launching: new ideas and collaborations! 🚀 The Department of Computational and Systems Biology held its annual retreat at the Kamin Science Center last week. Read more: shorturl.at/nZC95shorturl.atDepartment of Computational and Systems Biology hosts 2026 annual retreat at Kamin Science Center - Department of Computational and Systems BiologyThe Department of Computational and Systems Biology (CSB) hosted its annual retreat at the Kamin Science Center on May 7. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/04/2026To survive and succeed during finals week, remember to balance studying with self-care. Here are our tips for acing your tests while staying healthy. Good luck on your exams! tinyurl.com/5FinalsTipstinyurl.com5 tips for success during finals week - Department of Computational and Systems BiologyTo survive and succeed during finals week, remember to balance studying with self-care. Here are our tips for acing your tests while staying healthy. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/04/2026PhD candidate Swapnil Keshari was recognized with two leadership awards! Keshari received the Leadership & Service Award from Graduate and Professional Student Government and was also honored as a Student Sustainability Champion for 2026. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/04/2026The Department of Computational and Systems Biology has a new home! CSB will relocate to the top floor of a newly constructed 10-story building on Fifth Avenue and Halket Street. The move has already begun and should conclude by April 22. Read more: tinyurl.com/CSBFifthHalket 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 31/03/2026How did SARS-CoV-2 variants acquire dozens of mutations during the pandemic? New research from the Barton Lab investigates how such divergent, highly mutated variants could arise. Read the full research in Virus Evolution: tinyurl.com/BartonSARS2tinyurl.comChronic infections can generate SARS-CoV-2-like bursts of viral evolution without epistasisMultiple SARS-CoV-2 variants have arisen during the first years of the pandemic, often bearing many new mutations. Several explanations have been offered for the surprisingly sudden emergence of multiple mutations that enhance viral fitness, ... 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 25/03/2026What is it about a master’s degree that can set you apart from other job candidates? Beyond the personal fulfilment of earning your diploma, there are tangible career benefits to pursuing a master’s degree in Computational Biomedicine and Biotechnology. www.csb.pitt.edu/2026/03/25/5...csb.pitt.edu5 benefits of earning a master’s degree in Computational Biomedicine and Biotechnology - Department of Computational and Systems BiologyWhat is it about a master’s degree that can set you apart from other candidates in the job market? Beyond the personal fulfilment of earning your diploma, there are tangible career benefits to pursuin... 001
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/03/2026The Gur lab has published a new article in JACS Au, a journal of the American Chemical Society, that sheds light on how a promising class of cancer-fighting molecules works at the atomic level. Read more about the research on protein phosphate 2A, an "off-switch" for cancer: tinyurl.com/JACSPP2A 011
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/03/2026What word would Jennifer Watt use to describe herself? Resilient. This word perfectly captures how the administrative manager has overcome setbacks to thrive in all aspects of her life, from running ultramarathons to building a new career. Read more in our staff spotlight: tinyurl.com/JenniferWatt 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/02/2026From a young age, Warren van Loggerenberg dreamed of becoming a professor. That dream is now becoming reality as he transitions from a research scientist to an assistant professor. Learn more about Warren in our faculty spotlight: tinyurl.com/WarrenSpotli...tinyurl.comFaculty Spotlight: Warren van Loggerenberg - Department of Computational and Systems BiologyFrom a young age, Warren van Loggerenberg dreamed of becoming a professor. That dream is now becoming reality as he transitions from a research scientist to an assistant professor in the Department of... 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 24/02/2026Today's the day for Pitt Day of Giving! Join us in making an impact to ensure that we have the latest tools and resources to stay at the forefront of research, discovery, and training. ⏰ Giving ends at midnight. ➡️ Donate today: tinyurl.com/CSBGivetinyurl.comComputational and Systems Biology Fund - Pitt Day of GivingThe pipeline of new medical breakthroughs begins upstream, with fundamental discoveries. The Department of Computational and Systems Biology (CSB) is harnessing advanced computational methods and syst... 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 18/02/2026There is a growing need for bioinformatics professionals who can manage and interpret extensive genetic datasets. Have you ever wondered how to become a bioinformatics scientist? Check out this blog post: tinyurl.com/Bioinformati...tinyurl.comHow a master’s degree can jump-start your bioinformatics career - Department of Computational and Systems BiologyHave you ever wondered where a master’s degree in Computational Biomedicine and Biotechnology (CoBB) will take you? Read on to learn more about the bioinformatics scientist profession. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/02/2026Join us in welcoming Professor Kate Rubins and Professor Sylvain Costes to the CSB faculty! Rubins and Costes are founding members of the Trivedi Institute for Space and Global Biomedicine. We can't wait to see what these two will accomplish at Pitt! 020
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/02/2026Assistant Professor Yu-Chih Chen's new research is enabling more precise detection of cells that are resistant to cancer treatment (PGCCs). They also made these findings accessible via their PGCC Explorer, an interactive web tool for drug discovery. Read more: tinyurl.com/PGCCExplorertinyurl.comHigh-throughput drug screening for targeting polyploid cancer cells with an interactive web portal 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 05/02/2026PhD student Sophia Hu and Professor Jianhua Xing’s lab have developed a computational method to demystify what happens when cells go through epithelial-to-mesenchymal transition (EMT). Read more: tinyurl.com/HuEMT #BiologyResearchtinyurl.comNew study reveals cells take two different paths during EMT - Department of Computational and Systems BiologyPhD student Sophia Hu and Professor Jianhua Xing’s lab have developed a computational method to demystify what happens when cells go through epithelial-to-mesenchymal transition (EMT). 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 03/02/2026🚀 Now launching: the Trivedi Institute for Space and Global Biomedicine! Professor Kate Rubins, a former NASA astronaut, will lead this institute. It will focus on applying insights from spaceflight to improve human health on Earth. Read more: tinyurl.com/TrivediPitttinyurl.comPitt’s new Trivedi Institute will translate space science into human health breakthroughsFormer NASA astronaut and Professor Kate Rubins will lead the $25 million institute, funded by the Trivedi Family Foundation. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 27/01/2026CoBB alumnus Sahil Ganatra is stepping into a new role as a clinical study manager for Philips. He will oversee clinical trials that are focused on validating and testing medical devices for sleep and respiratory care diseases. Read more in our alumni spotlight: tinyurl.com/SahilGanatratinyurl.comAlumnus Sahil Ganatra is bridging the gap between technology and clinical care - Department of Computational and Systems BiologySahil Ganatra, a graduate of the Computational Biomedicine and Biotechnology (CoBB) master’s degree program, is bridging the gap between technology and clinical care. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/01/2026Pitt researchers are raising the bar for microprotein discovery. By reassessing detection methods, Aaron Wacholder and Anne-Ruxandra Carvunis reveal why standardized protocols are essential for uncovering these elusive proteins' roles in health and disease. tinyurl.com/NatureWachol...tinyurl.comCommunity benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics - PubMedThousands of short open reading frames (sORFs) are translated outside of annotated coding sequences. Recent studies have pioneered searching for sORF-encoded microproteins in mass spectrometry (MS)-based proteomics and peptidomics datasets. Here, we assessed literature-reported MS-based identificati … 011
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 14/01/2026A new study reveals how gene orf143 emerged "from scratch" in primate ancestors and may now protect against cancer. Led by Lin Chou and Anne Carvunis, this research shows evolution creating new genes in real time—with implications for cancer biology. Read more: tinyurl.com/ChouCarvunistinyurl.comEmergence and tandem repeat-mediated elongation of a translated de novo open reading frame in human oncogenic RNA gene VPS9D1-AS1 (MYU) - PubMedNew protein-coding genes can arise de novo from ancestrally noncoding regions when open reading frames (ORFs) outside annotated genes are exposed to selection via pervasive translation. These ORFs are usually born short, and their elongation is considered a key step in de novo gene birth. However, m … 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/01/2026In 2025, the CSB department tackled complex problems at the intersection of biology and technology. We came together in a mission of education and discovery. As we reflect on the impact of the last year, we’ve compiled our favorite stories from 2025. Read more: tinyurl.com/CSB2025Reviewtinyurl.comYear in review: 4 impactful moments for CSB in 2025 - Department of Computational and Systems BiologyIn 2025, the Department of Computational and Systems Biology tackled complex problems at the intersection of biology and technology. As we reflect on the impact of the last year, we’ve compiled our fa... 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 19/12/2025🎓Congratulations to Murdo Chiknas, who graduated from the Computational Biomedicine and Biotechnology master’s degree program! His next step is becoming the first person in his family to earn a PhD. Read more in our grad spotlight tinyurl.com/MurdoChiknastinyurl.comGraduate Spotlight: Peter Murdo Chiknas, MS ‘25 - Department of Computational and Systems BiologyPeter Murdo Chiknas reflects on his experiences in the Computational Biomedicine and Biotechnology master's program and his next steps after graduation. 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 17/12/2025🎓 A big shout out to Steven Smeal, who graduated from the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology! His next adventure is working as a postdoctoral associate at Carnegie Mellon University. Read more in this grad spotlight story: tinyurl.com/StevenSmealtinyurl.comGraduate Spotlight: Steven Smeal, PhD ‘25 - Department of Computational and Systems BiologySteven Smeal, a recent graduate of the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology (CPCB), reflects on the graduate school experiences that have helped to jumps... 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/12/2025Congratulations to Jessie Weng, a 2025 graduate! She leaves students with some advice: “Trust the process. Some of you might just be waiting on graduation to be done, but be curious about what you’re doing now, too. At the end of the day, curiosity pays off.” Read more: tinyurl.com/JessieWengtinyurl.comGraduate Spotlight: Jessie Weng, MS '25 - Department of Computational and Systems BiologyJessie Weng always knew she wanted to work in the health care industry, but she wasn’t sure which direction her career would go. The Computational Biomedicine and Biotechnology (CoBB) master’s degree ... 000
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 03/12/2025New research alert from the Lee lab! CPCB students Annie Kim and Ben Krummenacher, with ISB’s Jason Yeung, leverage naturally occurring variations of interleukin (IL)-1β from multiple species to determine the impact of affinity on human IL-1 receptor signaling. Read more: tinyurl.com/LeeLabResearchtinyurl.comNEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinityKim et al. leverage natural variation in IL-1β affinity across species to show that while ligand affinity sets activation thresholds, each IL-1 receptor signaling complex outputs a fixed, quantized bu... 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 25/11/2025Donating a little bit of time can make a big impact. On Nov. 21, members of the Department of Computational and Systems Biology spent the day volunteering at Cribs for Kids, assembling 1,000 safe-sleep survival kits for infants. Read more about our volunteering event: tinyurl.com/CribsforKids...tinyurl.comCSB members assemble 1,000 safe-sleep kits for infants at Cribs for Kids - Department of Computational and Systems BiologyDonating a little bit of time can make a big impact. On Nov. 21, members of the Department of Computational and Systems Biology (CSB) spent the day volunteering at Cribs for Kids. 010
Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 18/11/2025Emeritus Professor Hagai Meirovitch returned to the University of Pittsburgh for a visit last week. “I see many new people, so I think this a good sign that the place is growing and breathing,” he said. “I see progress and a future for the department that we worked to create.” tinyurl.com/HagaiMtinyurl.comEmeritus Professor Hagai Meirovitch reflects on time at Pitt - Department of Computational and Systems BiologyEmeritus Professor Hagai Meirovitch returned to the University of Pittsburgh for a visit last week. 000