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Computational & Systems Biology Dept. at Pitt

@csbpitt.bsky.social
549 followers 61 following 111 posts

Harnessing the power of computational & systems-level analyses to solve critical biological problems, and training the next generation of multidisciplinary scientists. Visit www.csb.pitt.edu

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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/09/2026
Congratulations to our students and professors who received awards from the Biomedical Graduate Student Association! Jishnu Das was recognized as a Distinguished Mentor of the Year finalist. PhD student Alisa Omelchenko was named the Most Well-Rounded Student of the Year. tinyurl.com/BGSA2026
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/09/2026
Mehmet Hocaoglu is a practicing rheumatologist and a student in the Computational Biomedicine and Biotechnology MS program. The CoBB program offered Hocaoglu the opportunity to take classes to support his research interests in the clinic. Read more: tinyurl.com/MehmetCoBB
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Graduate student Mehmet Hocaoglu applies computational techniques to clinical research - Department of Computational and Systems Biology
Mehmet Hocaoglu is a practicing rheumatologist and a student in the Computational Biomedicine and Biotechnology (CoBB) MS program.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/09/2026
PhD student Alisa Omelchenko is making strides in the community as a 2026 Pittsburgh 40 under 40 honoree. Omelchenko and the other selected individuals, all under the age of 40, will be honored at an annual awards event in November. Read more: tinyurl.com/Alisa40Under40
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Alisa Omelchenko honored as Pittsburgh 40 Under 40 awardee - Department of Computational and Systems Biology
PhD student Alisa Omelchenko is making strides in the community as a 2026 Pittsburgh 40 under 40 honoree.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/08/2026
How can lab techniques be adapted with gravity in mind for use on the International Space Station? Professor Kate Rubins, director of the Trivedi Institute for Space and Global Biomedicine, answer this question in an article recently published in Science. Read the story: tinyurl.com/RubinsISS
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Dreams of making drugs and tissues in space get closer to reality
Maturing techniques and cheaper launches fuel microgravity research—and hopes of orbital manufacturing
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 27/08/2026
The CPCB 20th Anniversary Research Symposium was held on Aug. 20 and 21 and celebrated two decades of success in PhD training for the CMU-PITT Computational Biology PhD Program. Read more about the event: tinyurl.com/CPCB20th
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/08/2026
Congratulations to PhD student Anamarie Martinez-Turak, who has received the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (F31). Learn more: tinyurl.com/MartinezTurak
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/08/2026
Today was a day for curiosity and camaraderie! Students, alumni and faculty gathered at The Assembly today for the CPCB 20th Anniversary Research Symposium, which celebrates two decades of excellence in training and discovery for the CMU-PITT Computational Biology PhD Program.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 20/08/2026
Assistant Professor Keisuke Ishihara’s lab has released a new preprint that sheds light on the development of human cardioids, which are lab-made miniature heart tissue. Read more about the research: tinyurl.com/IshiharaHeart
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Study reveals role of hyaluronic acid in human heart development - Department of Computational and Systems Biology
Assistant Professor Keisuke Ishihara’s lab has released a new preprint that sheds light on the development of human cardioids, which are lab-made miniature heart tissue.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/08/2026
Laura Tipton realized that she wanted to ask her own research questions. This led her on a path to earning her PhD in computational biology. The CPCB graduate is now an assistant professor of environmental data science at James Madison University. Read more about Tipton: tinyurl.com/Laura-Tipton
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CPCB Alumni Success Story: Laura Tipton - Department of Computational and Systems Biology
Laura Tipton is an assistant professor of environmental data science at James Madison University, where she pursues the research questions of her choice in her biology lab.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/08/2026
The beginning of the fall semester is only a few weeks away! If you are a new student, you may have questions about what to expect for your first year at Pitt. We've created this new student survival guide with important information on campus resources. Read the guide: tinyurl.com/NewStudent26
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2026 New Student Survival Guide - Department of Computational and Systems Biology
We’re sure you have many questions about life at Pitt, so we’ve assembled a list of frequently asked questions to make your transition to campus a little easier.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 06/08/2026
New research from Warren van Loggerenberg and Fritz Roth sheds light on the variants that cause APS-1, a rare immunodeficiency disease. They assessed the function of 9,790 of these pathogenic variants in their variant effect map. Read the full research article: tinyurl.com/RothVariants
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Systematic and proactive evaluation of AIRE missense variant effects
Pathogenic variants in the autoimmune regulator (AIRE) cause autoimmune polyendocrine syndrome type 1 (APS-1), a rare primary immunodeficiency disease…
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/07/2026
Graduate student Hamid Javanshir has always been passionate about the power of research to improve patients' lives. He has a provisional patent application underway for the cancer drug candidates he designed through his computational research. Read more about his work: tinyurl.com/JavanshirRes...
Hamid Javanshir pursues patent for pancreatic cancer research
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 24/07/2026
CoBB graduate student Maura O'Malley has had a busy summer filled with preparing for graduation and gaining experience as a research intern at Mass General Brigham in Boston. Read more about Maura in our graduate spotlight: tinyurl.com/MauraCoBB
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Graduate Spotlight: Maura O’Malley, MS ‘26 - Department of Computational and Systems Biology
Maura O’Malley is preparing for graduation from the computational Biomedicine and Biotechnology master's degree program while making an impact as a research intern at Mass General Brigham.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/07/2026
Congratulations to Assistant Professor Nate Lord, who has been awarded a grant from the National Science Foundation’s Faculty Early Career Development Program (CAREER)! Read more about the CAREER award: tinyurl.com/LordCAREER
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Nate Lord earns Faculty Early Career Development (CAREER) award from the NSF - Department of Computational and Systems Biology
Assistant Professor Nate Lord has been awarded a grant from the National Science Foundation’s Faculty Early Career Development Program (CAREER).
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/07/2026
Assistant Professor Shikhar Uttam is among a group of 16 research teams awarded $35 million in funding over three years to study new approaches for prevention, early detection and interception of BRCA-related cancers. Learn more about the award: tinyurl.com/UttamGrant
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Pitt Researchers Among Recipients of $35M for BRCA-Related Cancer Research | School of Medicine | University of Pittsburgh
T. Rinda Soong (left), assistant professor of pathology, and Shikhar Uttam (right), assistant professor of computational and systems biology, both in the School of Medicine, University of Pittsburgh, ...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/07/2026
Meet Avery Mills, a former CompBio Academy student who is interning in the Roth lab this summer! Learn more about Avery and her summer research on variant effect maps. tinyurl.com/AveryMills
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Meet the Intern: Avery Mills - Department of Computational and Systems Biology
Meet Avery Mills, a former CompBio Academy student who is interning in the Roth lab this summer!
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 30/06/2026
For Associate Professor Jim Faeder, no mountain is too high. 🏔️ This summer, he got out of the lab and onto the trail. Faeder traveled to Peru and hiked to the summit of Machu Picchu. Read more about his incredible trip in this summer story: tinyurl.com/FaederTrek
Machu PicchuMachu Picchu
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 29/06/2026
Our students are presenting their work across the country! Congratulations to PhD student Anamarie Martinez, who won a travel award to attend the FASEB Dynamics and Encoding in Cell Signaling Conference in Nashville. She presented a poster and delivered a flash talk at the conference.
Anamarie Martinez at FASEBAnamarie Martinez at FASEB
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 23/06/2026
Shannon Quinn is driven by solving problems that lead to advances in drug discovery. The graduate of the CMU-PITT Computational Biology PhD Program now works as a senior staff machine learning engineer at Valo Health. Read more about Quinn in our alumni success story: tinyurl.com/ShannonQuinn
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CPCB Alumni Success Story: Shannon Quinn - Department of Computational and Systems Biology
Shannon Quinn is driven by solving complex problems that lead to advances in drug discovery.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 17/06/2026
Congratulations to Professor Jianhua Xing, who received a grant from the National Institute of General Medical Sciences! This grant will support Xing’s project on quiescence and senescence. Learn more about the research: tinyurl.com/XingNIGMS
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Jianhua Xing awarded grant from National Institute of General Medical Sciences - Department of Computational and Systems Biology
Professor Jianhua Xing received an R01 grant from the National Institute of General Medical Sciences (NIGMS).
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/06/2026
Spring cleaning isn't just for closets 💻 This month, take 15 minutes to clear out old files in OneDrive and SharePoint. The time you spend helps to reduce Pitt’s carbon footprint. #DigitalSpringCleaning
Digital Spring Cleaning Challenge
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/06/2026
Check out our new home at Fifth and Halket!
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/06/2026
Congratulations to Associate Professor John Barton, who has received a Maximizing Investigators’ Research Award from the National Institutes of Health! Read more about the award: tinyurl.com/BartonNIH
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/05/2026
Let's unlock curiosity and pursue discovery this summer! Undergraduate students have arrived for the TECBio REU program, a 10-week summer program that provides a challenging and fulfilling graduate-level research experience in computational biology.
2026 TECBio students
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 14/05/2026
Ericka Mochan always knew she wanted to be a teacher. In our alumni success story, the Chair of the Department of Computational and Chemical Sciences at Carlow University reflects on how earning her computational biology PhD helped her achieve a dream career. tinyurl.com/ErickaMochan
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CPCB Alumni Success Story: Ericka Mochan - Department of Computational and Systems Biology
Mochan is a graduate of the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology (CPCB) and currently serves as the Chair of the Department of Computational and Chemical...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/05/2026
Now launching: new ideas and collaborations! 🚀 The Department of Computational and Systems Biology held its annual retreat at the Kamin Science Center last week. Read more: shorturl.at/nZC95
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Department of Computational and Systems Biology hosts 2026 annual retreat at Kamin Science Center - Department of Computational and Systems Biology
The Department of Computational and Systems Biology (CSB) hosted its annual retreat at the Kamin Science Center on May 7.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 28/04/2026
To survive and succeed during finals week, remember to balance studying with self-care. Here are our tips for acing your tests while staying healthy. Good luck on your exams! tinyurl.com/5FinalsTips
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5 tips for success during finals week - Department of Computational and Systems Biology
To survive and succeed during finals week, remember to balance studying with self-care. Here are our tips for acing your tests while staying healthy.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/04/2026
PhD candidate Swapnil Keshari was recognized with two leadership awards! Keshari received the Leadership & Service Award from Graduate and Professional Student Government and was also honored as a Student Sustainability Champion for 2026.
Congratulations Swapnil Keshari
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/04/2026
The Department of Computational and Systems Biology has a new home! CSB will relocate to the top floor of a newly constructed 10-story building on Fifth Avenue and Halket Street. The move has already begun and should conclude by April 22. Read more: tinyurl.com/CSBFifthHalket
Fifth and Halket buildingFifth and Halket building
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 31/03/2026
How did SARS-CoV-2 variants acquire dozens of mutations during the pandemic? New research from the Barton Lab investigates how such divergent, highly mutated variants could arise. Read the full research in Virus Evolution: tinyurl.com/BartonSARS2
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Chronic infections can generate SARS-CoV-2-like bursts of viral evolution without epistasis
Multiple SARS-CoV-2 variants have arisen during the first years of the pandemic, often bearing many new mutations. Several explanations have been offered for the surprisingly sudden emergence of multiple mutations that enhance viral fitness, ...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 25/03/2026
What is it about a master’s degree that can set you apart from other job candidates? Beyond the personal fulfilment of earning your diploma, there are tangible career benefits to pursuing a master’s degree in Computational Biomedicine and Biotechnology. www.csb.pitt.edu/2026/03/25/5...
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5 benefits of earning a master’s degree in Computational Biomedicine and Biotechnology - Department of Computational and Systems Biology
What is it about a master’s degree that can set you apart from other candidates in the job market? Beyond the personal fulfilment of earning your diploma, there are tangible career benefits to pursuin...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/03/2026
The Gur lab has published a new article in JACS Au, a journal of the American Chemical Society, that sheds light on how a promising class of cancer-fighting molecules works at the atomic level. Read more about the research on protein phosphate 2A, an "off-switch" for cancer: tinyurl.com/JACSPP2A
protein phosphate 2A
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 09/03/2026
What word would Jennifer Watt use to describe herself? Resilient. This word perfectly captures how the administrative manager has overcome setbacks to thrive in all aspects of her life, from running ultramarathons to building a new career. Read more in our staff spotlight: tinyurl.com/JenniferWatt
Jennifer Watt on the Appalachian TrailJennifer Watt on the Appalachian Trail
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 26/02/2026
From a young age, Warren van Loggerenberg dreamed of becoming a professor. That dream is now becoming reality as he transitions from a research scientist to an assistant professor. Learn more about Warren in our faculty spotlight: tinyurl.com/WarrenSpotli...
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Faculty Spotlight: Warren van Loggerenberg - Department of Computational and Systems Biology
From a young age, Warren van Loggerenberg dreamed of becoming a professor. That dream is now becoming reality as he transitions from a research scientist to an assistant professor in the Department of...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 24/02/2026
Today's the day for Pitt Day of Giving! Join us in making an impact to ensure that we have the latest tools and resources to stay at the forefront of research, discovery, and training. ⏰ Giving ends at midnight. ➡️ Donate today: tinyurl.com/CSBGive
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Computational and Systems Biology Fund - Pitt Day of Giving
The pipeline of new medical breakthroughs begins upstream, with fundamental discoveries. The Department of Computational and Systems Biology (CSB) is harnessing advanced computational methods and syst...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 18/02/2026
There is a growing need for bioinformatics professionals who can manage and interpret extensive genetic datasets. Have you ever wondered how to become a bioinformatics scientist? Check out this blog post: tinyurl.com/Bioinformati...
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How a master’s degree can jump-start your bioinformatics career - Department of Computational and Systems Biology
Have you ever wondered where a master’s degree in Computational Biomedicine and Biotechnology (CoBB) will take you? Read on to learn more about the bioinformatics scientist profession.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 12/02/2026
Join us in welcoming Professor Kate Rubins and Professor Sylvain Costes to the CSB faculty! Rubins and Costes are founding members of the Trivedi Institute for Space and Global Biomedicine. We can't wait to see what these two will accomplish at Pitt!
Kate RubinsSylvain Costes
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 11/02/2026
Assistant Professor Yu-Chih Chen's new research is enabling more precise detection of cells that are resistant to cancer treatment (PGCCs). They also made these findings accessible via their PGCC Explorer, an interactive web tool for drug discovery. Read more: tinyurl.com/PGCCExplorer
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High-throughput drug screening for targeting polyploid cancer cells with an interactive web portal
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 05/02/2026
PhD student Sophia Hu and Professor Jianhua Xing’s lab have developed a computational method to demystify what happens when cells go through epithelial-to-mesenchymal transition (EMT). Read more: tinyurl.com/HuEMT #BiologyResearch
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New study reveals cells take two different paths during EMT - Department of Computational and Systems Biology
PhD student Sophia Hu and Professor Jianhua Xing’s lab have developed a computational method to demystify what happens when cells go through epithelial-to-mesenchymal transition (EMT).
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 03/02/2026
🚀 Now launching: the Trivedi Institute for Space and Global Biomedicine! Professor Kate Rubins, a former NASA astronaut, will lead this institute. It will focus on applying insights from spaceflight to improve human health on Earth. Read more: tinyurl.com/TrivediPitt
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Pitt’s new Trivedi Institute will translate space science into human health breakthroughs
Former NASA astronaut and Professor Kate Rubins will lead the $25 million institute, funded by the Trivedi Family Foundation.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 27/01/2026
CoBB alumnus Sahil Ganatra is stepping into a new role as a clinical study manager for Philips. He will oversee clinical trials that are focused on validating and testing medical devices for sleep and respiratory care diseases. Read more in our alumni spotlight: tinyurl.com/SahilGanatra
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Alumnus Sahil Ganatra is bridging the gap between technology and clinical care - Department of Computational and Systems Biology
Sahil Ganatra, a graduate of the Computational Biomedicine and Biotechnology (CoBB) master’s degree program, is bridging the gap between technology and clinical care.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 21/01/2026
Pitt researchers are raising the bar for microprotein discovery. By reassessing detection methods, Aaron Wacholder and Anne-Ruxandra Carvunis reveal why standardized protocols are essential for uncovering these elusive proteins' roles in health and disease. tinyurl.com/NatureWachol...
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Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics - PubMed
Thousands of short open reading frames (sORFs) are translated outside of annotated coding sequences. Recent studies have pioneered searching for sORF-encoded microproteins in mass spectrometry (MS)-based proteomics and peptidomics datasets. Here, we assessed literature-reported MS-based identificati …
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 14/01/2026
A new study reveals how gene orf143 emerged "from scratch" in primate ancestors and may now protect against cancer. Led by Lin Chou and Anne Carvunis, this research shows evolution creating new genes in real time—with implications for cancer biology. Read more: tinyurl.com/ChouCarvunis
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Emergence and tandem repeat-mediated elongation of a translated de novo open reading frame in human oncogenic RNA gene VPS9D1-AS1 (MYU) - PubMed
New protein-coding genes can arise de novo from ancestrally noncoding regions when open reading frames (ORFs) outside annotated genes are exposed to selection via pervasive translation. These ORFs are usually born short, and their elongation is considered a key step in de novo gene birth. However, m …
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 08/01/2026
In 2025, the CSB department tackled complex problems at the intersection of biology and technology. We came together in a mission of education and discovery. As we reflect on the impact of the last year, we’ve compiled our favorite stories from 2025. Read more: tinyurl.com/CSB2025Review
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Year in review: 4 impactful moments for CSB in 2025 - Department of Computational and Systems Biology
In 2025, the Department of Computational and Systems Biology tackled complex problems at the intersection of biology and technology. As we reflect on the impact of the last year, we’ve compiled our fa...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 19/12/2025
🎓Congratulations to Murdo Chiknas, who graduated from the Computational Biomedicine and Biotechnology master’s degree program! His next step is becoming the first person in his family to earn a PhD. Read more in our grad spotlight tinyurl.com/MurdoChiknas
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Graduate Spotlight: Peter Murdo Chiknas, MS ‘25 - Department of Computational and Systems Biology
Peter Murdo Chiknas reflects on his experiences in the Computational Biomedicine and Biotechnology master's program and his next steps after graduation.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 17/12/2025
🎓 A big shout out to Steven Smeal, who graduated from the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology! His next adventure is working as a postdoctoral associate at Carnegie Mellon University. Read more in this grad spotlight story: tinyurl.com/StevenSmeal
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Graduate Spotlight: Steven Smeal, PhD ‘25 - Department of Computational and Systems Biology
Steven Smeal, a recent graduate of the Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology (CPCB), reflects on the graduate school experiences that have helped to jumps...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 10/12/2025
Congratulations to Jessie Weng, a 2025 graduate! She leaves students with some advice: “Trust the process. Some of you might just be waiting on graduation to be done, but be curious about what you’re doing now, too. At the end of the day, curiosity pays off.” Read more: tinyurl.com/JessieWeng
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Graduate Spotlight: Jessie Weng, MS '25 - Department of Computational and Systems Biology
Jessie Weng always knew she wanted to work in the health care industry, but she wasn’t sure which direction her career would go. The Computational Biomedicine and Biotechnology (CoBB) master’s degree ...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 03/12/2025
New research alert from the Lee lab! CPCB students Annie Kim and Ben Krummenacher, with ISB’s Jason Yeung, leverage naturally occurring variations of interleukin (IL)-1β from multiple species to determine the impact of affinity on human IL-1 receptor signaling. Read more: tinyurl.com/LeeLabResearch
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NEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinity
Kim et al. leverage natural variation in IL-1β affinity across species to show that while ligand affinity sets activation thresholds, each IL-1 receptor signaling complex outputs a fixed, quantized bu...
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 25/11/2025
Donating a little bit of time can make a big impact. On Nov. 21, members of the Department of Computational and Systems Biology spent the day volunteering at Cribs for Kids, assembling 1,000 safe-sleep survival kits for infants. Read more about our volunteering event: tinyurl.com/CribsforKids...
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CSB members assemble 1,000 safe-sleep kits for infants at Cribs for Kids - Department of Computational and Systems Biology
Donating a little bit of time can make a big impact. On Nov. 21, members of the Department of Computational and Systems Biology (CSB) spent the day volunteering at Cribs for Kids.
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Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · 18/11/2025
Emeritus Professor Hagai Meirovitch returned to the University of Pittsburgh for a visit last week. “I see many new people, so I think this a good sign that the place is growing and breathing,” he said. “I see progress and a future for the department that we worked to create.” tinyurl.com/HagaiM
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Emeritus Professor Hagai Meirovitch reflects on time at Pitt - Department of Computational and Systems Biology
Emeritus Professor Hagai Meirovitch returned to the University of Pittsburgh for a visit last week.
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