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John Rittenhouse

@cryect.bsky.social
505 followers 509 following 754 posts

VR Software developer for past ten years currently working at OssoVR on surgical training

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John Rittenhouse @cryect.bsky.social · 26/08/2026
Answer it never returns to the starting position as they start in the top left corner and go to the top right corner. There is though 363 dots so if it was a closed loop it would taken 60 minutes and 30 seconds to loop.
Hilbert curve of the path the dots follow from the ten second looping video.
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John Rittenhouse @cryect.bsky.social · 04/08/2026
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John Rittenhouse @cryect.bsky.social · 26/07/2026
More appropriate with this instead
The Muppet named Animal making a funny open mouth have and posed with head ninety degrees to the side
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John Rittenhouse @cryect.bsky.social · 22/02/2026
Calvin and Hobbes where Calvin in the future expects his past self to have some his homework who went to the future expecting to retrieve it already done.
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John Rittenhouse @cryect.bsky.social · 08/12/2025
Seen here attempts to turn the Titanic back to where it could float.
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John Rittenhouse @cryect.bsky.social · 16/08/2025
Had to go check my first 10 on Steam as well and seems the really old purchases are actually in license activations.
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John Rittenhouse @cryect.bsky.social · 26/04/2025
I ain't reading all that
I'm happy for u tho
Or sorry that happened
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John Rittenhouse @cryect.bsky.social · 18/03/2025
Two planes ere heading to Honduras with none of them having landed yet. In fact, a third plane actually took off after the order was even in the docket. www.washingtonpost.com/immigration/...
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John Rittenhouse @cryect.bsky.social · 12/03/2025
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John Rittenhouse @cryect.bsky.social · 10/02/2025
Well good summary of this is extremely wasteful of taxpayer's dollars.
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John Rittenhouse @cryect.bsky.social · 17/01/2025
Yes, the planet got destroyed. But for a brief moment we had our norms.
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John Rittenhouse @cryect.bsky.social · 20/12/2024
Used the 1.28" round touch LCD one for this project.
Project with five rotary dials and a round touch LCD screen in the middle.
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John Rittenhouse @cryect.bsky.social · 18/12/2024
Didn't realize Pacific Drive was at top of my time played for the year. Against the Storm and Enshrouded don't surprise me though.
Steam Replay 2024 for Cryect.  45 games played, 415 achievements, 86% Keyboard and mouse, 9% time on Pacific Drive, 7% Against the Storm, and 7% Enshrouded
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John Rittenhouse @cryect.bsky.social · 07/12/2024
@hankgreen.bsky.social I got curious on the cervical cancer video and how Claude approached being asked about why stage 0 cervical cancer were exposed it and it seemed to do a pretty good job.
Claude chat
John
Why when studying the effectiveness of HPV vaccines do they only look at invasive cervical cancer and exclude stage 0 cervical cancer?

 The focus on invasive cervical cancer (stages I-IV) rather than stage 0 (carcinoma in situ/CIN3) in HPV vaccine studies stems from several important methodological and clinical considerations:

1. Natural History: Many stage 0 lesions regress spontaneously without treatment, especially in younger women. Including these cases could make it harder to determine the true protective effect of the vaccine since some improvements might happen naturally.

2. Clinical Significance: Invasive cervical cancer represents the most important health outcome, as it has the greatest impact on mortality and morbidity. Stage 0 is considered pre-cancer and is highly treatable with nearly 100% survival rates.

3. Time to Outcome: Stage 0 occurs relatively quickly after HPV infection, while invasive cancer typically takes 10-20 years to develop. Looking at invasive cancer provides better evidence of long-term vaccine protection.

4. Statistical Power: Including stage 0 cases could potentially dilute the statistical power to detect the vaccine's effect on preventing the more serious invasive cancers.

However, many studies do look at CIN2+ and CIN3+ as secondary endpoints since these are important precursor lesions. Would you like me to explain more about how these different endpoints are used in vaccine research?Claude chat
John
Why when studying the effectiveness of HPV vaccines do they only look at invasive cervical cancer and exclude stage 0 cervical cancer?

 The focus on invasive cervical cancer (stages I-IV) rather than stage 0 (carcinoma in situ/CIN3) in HPV vaccine studies stems from several important methodological and clinical considerations:

1. Natural History: Many stage 0 lesions regress spontaneously without treatment, especially in younger women. Including these cases could make it harder to determine the true protective effect of the vaccine since some improvements might happen naturally.

2. Clinical Significance: Invasive cervical cancer represents the most important health outcome, as it has the greatest impact on mortality and morbidity. Stage 0 is considered pre-cancer and is highly treatable with nearly 100% survival rates.

3. Time to Outcome: Stage 0 occurs relatively quickly after HPV infection, while invasive cancer typically takes 10-20 years to develop. Looking at invasive cancer provides better evidence of long-term vaccine protection.

4. Statistical Power: Including stage 0 cases could potentially dilute the statistical power to detect the vaccine's effect on preventing the more serious invasive cancers.

However, many studies do look at CIN2+ and CIN3+ as secondary endpoints since these are important precursor lesions. Would you like me to explain more about how these different endpoints are used in vaccine research?Claude chat
John
Why when studying the effectiveness of HPV vaccines do they only look at invasive cervical cancer and exclude stage 0 cervical cancer?

 The focus on invasive cervical cancer (stages I-IV) rather than stage 0 (carcinoma in situ/CIN3) in HPV vaccine studies stems from several important methodological and clinical considerations:

1. Natural History: Many stage 0 lesions regress spontaneously without treatment, especially in younger women. Including these cases could make it harder to determine the true protective effect of the vaccine since some improvements might happen naturally.

2. Clinical Significance: Invasive cervical cancer represents the most important health outcome, as it has the greatest impact on mortality and morbidity. Stage 0 is considered pre-cancer and is highly treatable with nearly 100% survival rates.

3. Time to Outcome: Stage 0 occurs relatively quickly after HPV infection, while invasive cancer typically takes 10-20 years to develop. Looking at invasive cancer provides better evidence of long-term vaccine protection.

4. Statistical Power: Including stage 0 cases could potentially dilute the statistical power to detect the vaccine's effect on preventing the more serious invasive cancers.

However, many studies do look at CIN2+ and CIN3+ as secondary endpoints since these are important precursor lesions. Would you like me to explain more about how these different endpoints are used in vaccine research?
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John Rittenhouse @cryect.bsky.social · 19/11/2024
Yep, and rails give you a nice path to follow before you blanket/place power lines everywhere. Only used drones really for the final tier. Son also loves jumping in a train and driving it around.
Looking over a Satisfactory city of skyscraper factories with a rail station and railways going elsewhere.
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John Rittenhouse @cryect.bsky.social · 04/11/2024
Supposedly has confirmed he does know after doubling down once.
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John Rittenhouse @cryect.bsky.social · 04/11/2024
If it works for The Emperor it works for him.
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John Rittenhouse @cryect.bsky.social · 01/11/2024
Poltergust G-00 turned out well for the son!
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John Rittenhouse @cryect.bsky.social · 03/10/2024
Definition of woke has gotten much broader than I realized.
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John Rittenhouse @cryect.bsky.social · 09/05/2024
Don't compare a real rate (real wage is inflation adjusted) to a nominal item (in this the CPI of rent). Here's the correct comparison. fred.stlouisfed.org/graph/?g=1nOJo
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