On Friday 27 June 2025, mothers, researchers, and a young adult patient came together for the first time in person in Cambridge.These mums and patient, who have formed a supportive online network…

Mutational signature analysis of blood cells isolated from 23 chemotherapy-exposed samples and 9 nonexposed controls characterizes the effects of various drugs on mutational burden, signature…

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukaemia, the commonest cancer in childhood and one that can be…

Jesus College was the venue for a family fun day in aid of young hospital patients and their families.Organised in partnership with the paediatric haematology a

Anaplastic Lymphoma Kinase inhibitors (ALK TKIs) are approved for the treatment of ALK-positive non-small cell lung cancer (NSCLC) and are in clinical trial for ALK-aberrant high-risk neuroblastoma…

Cancer predisposition syndromes mediated by recessive cancer genes generate tumors via somatic variants (second hits) in the unaffected allele. Second hits may or may not be sufficient for neoplastic…

Malignant germ cell tumours (GCTs) are complex cancers that affect patients of all ages. They develop from cells that produce eggs or sperm and mostly occur in the ovaries and testes.Around 2,500 men…

YouTube video by Cancer Research UK Cambridge Centre

In this work, published in the Molecular Oncology journal, the team identified a set of microRNAs found at low levels in malignant GCTs. When these microRNAs were reintroduced into tumour cells, and…

Highlighted Article: The enhanced activity of phosphomutant ASCL1 depends on more efficient chromatin remodelling during in vitro neurogenesis.

Jassim et al. introduce a graph-embedding computational pipeline (RECODR) that measures changes in gene co-expression context during cancer treatment. RECODR enables the design of highly effective…

She is the Training Lead for the Brain Cancer Virtual at the Cancer Research UK Cambridge Centre and a member of the Cancer Research UK Children's Brain Tumour Centre of Excellence. As an…

Hosted by The University of Cambridge and The Institute of Cancer Research, London

Meet Carla and Emily, PhD students at the University of Cambridge, members of the Cancer Research UK Cambridge Centre Childhood, Teenage and Young Adults Cancers Programme, and leaders of the Young…

Objectives To assess public awareness of the risks and symptoms of cancer in children, teenagers, and young adults (CTYA) aged <18 years in Great Britain. Methods A face-to-face computer-assisted…