iiinova — where your digital self keeps evolving

The Coster lab 🧬🔬 @costerlab.bsky.social · 02/10/2026

Had a fantastic time at the Ludwig AtoZ conference, lovely Oxford venue and weather and the cherry on top - proud supervisor moment as Billie won the best poster prize 👏

041

The Coster lab 🧬🔬 @costerlab.bsky.social · 28/09/2026

Arrived at Worcester college in Oxford for the Ludwig AtoZ DNA secondary structures conference. Looking forward to great science, catching up with colleagues and some punting too!

043

The Coster lab 🧬🔬 @costerlab.bsky.social · 19/07/2026

Arrived in scorching hot Pheonix, Arizona for the FASEB Dynamic DNA conference. Looking forward to great science and catching up with colleagues 😎

010

Reposted by The Coster lab 🧬🔬

McVey lab @mcveylab.bsky.social · 04/06/2026

Extended abstract deadline (June 7th) for FASEB Dynamic DNA Structures in Scottsdale, AZ July 19-24. Speaking slots still open, and scholarships available for trainees (grad students and postdocs). Let your colleagues know! events.faseb.org/event/Dynami...

events.faseb.org

0410

The Coster lab 🧬🔬 @costerlab.bsky.social · 18/12/2025

Read our latest work - a comprehensive review on how DNA secondary structures affect replication. Very proud of Adi, Maria and Billie for their monumental effort. They've covered a large body of literature while proposing updated models. Open Access in DNA Repair: doi.org/10.1016/j.dn...

sciencedirect.com

How DNA secondary structures drive replication fork instability

DNA secondary structures, such as hairpins, cruciforms, triplexes, G-quadruplexes and iMotifs, are common, dynamic features that replication forks rou…

1216

The Coster lab 🧬🔬 @costerlab.bsky.social · 14/11/2025

📢 Last days to apply! 📢 Fully funded PhD position, starting Oct 2026. Deadline Nov 16th. We provide a supportive environment and top notch facilities, helping you develop into an independent scientist. Project details: tinyurl.com/CosterPhD Apply: tinyurl.com/ApplyICR The lab: CosterLab.com

tinyurl.com

Typos in the genome: Defining the molecular mechanism of replication slippage

052

The Coster lab 🧬🔬 @costerlab.bsky.social · 10/10/2025

🧪📣 PhD studentship available! Please repost. Our lab has a fully funded PhD position, starting Oct 2026. We provide a supportive environment and top notch facilities, helping you develop into an independent scientist. Project details: tinyurl.com/CosterPhD How to apply: tinyurl.com/ApplyICR

icr.ac.uk

Typos in the genome: Defining the molecular mechanism of replication slippage

021

The Coster lab 🧬🔬 @costerlab.bsky.social · 03/09/2025

Congrats Alexis! Fantastic news and well deserved 🎉

020

The Coster lab 🧬🔬 @costerlab.bsky.social · 03/09/2025

Some repeats and structure-forming sequences are indeed difficult to clone, not because they are toxic, but because they are genetically unstable. Examples are AT and CGG repeats. If a sequence is problematic, cloning efficiency will be low, but clones you do get will have deletions in that area.

030

The Coster lab 🧬🔬 @costerlab.bsky.social · 02/09/2025

Are you having issues with a plasmid or are you trying to introduce a toxic sequence on purpose?

100

The Coster lab 🧬🔬 @costerlab.bsky.social · 01/09/2025

🎉 Congrats Mathew and Mike! Great to finally see this out. A fantastic tool for the replication community and beyond 👏

110

The Coster lab 🧬🔬 @costerlab.bsky.social · 09/07/2025

Congrats Hasan. Well deserved 🎉😁

110

The Coster lab 🧬🔬 @costerlab.bsky.social · 03/07/2025

Very cool to see MCM loading in action and with such detail. Years of genetic, biochemical and structural work from many labs distilled into a beautiful animation 🧬👍

030

The Coster lab 🧬🔬 @costerlab.bsky.social · 23/06/2025

Had a fun day in the sun, hosting the lab for a BBQ 🍔🥗🍺☀️ Great food and company 😁 I am so grateful and happy to work with such lovely people 😎

080

The Coster lab 🧬🔬 @costerlab.bsky.social · 13/06/2025

Congrats Puck and Koichi 🎉 Super exciting G4 biology 🧬

100

The Coster lab 🧬🔬 @costerlab.bsky.social · 12/06/2025

New lab member joining is a great excuse to eat out and take a new lab photo 🎉🍜📷

0102

The Coster lab 🧬🔬 @costerlab.bsky.social · 12/06/2025

Welcome to our newest lab member - Ellie Wright. She did her PhD with Matt Neale and will lead data analysis and omics in the lab as a Higher Scientific Officer 💻🧬

040

Reposted by The Coster lab 🧬🔬

Adrien Leger @adrienleger.bsky.social · 02/06/2025

🚨 We’re hiring ! 🚨 Join our cutting-edge research team as a molecular biologist at @nanoporetech.com HQ in Oxford. Perfect for a fresh PhD or MSc with a couple of years’ experience. Work at the interface of chemistry, molecular/synthetic biology and AI 👉 ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...

044

The Coster lab 🧬🔬 @costerlab.bsky.social · 29/03/2025

Great to have two lab alumni visit - Manolo @dazamartinlab.bsky.social and Sophie. Congrats to Manolo's son Javier on his first birthday 🎂🎊

051

The Coster lab 🧬🔬 @costerlab.bsky.social · 13/03/2025

📷 New lab photos 😎 Still undecided as to which one is better... But we all look so happy 😏

082

The Coster lab 🧬🔬 @costerlab.bsky.social · 13/03/2025

Had a fantastic day at the Genome Damage and Stability Center in Sussex. Lovely to see Brighton and have stimulating discussions with colleagues. Thanks Laurence Pearl for the invitation!

020

The Coster lab 🧬🔬 @costerlab.bsky.social · 06/03/2025

Congrats Dirk and team! Great work and good to finally see it out!

010

The Coster lab 🧬🔬 @costerlab.bsky.social · 24/01/2025

🎉🔬 The lab has expanded! Today we celebrated the joining of Adi and Maria, two postdocs, with great Vietnamese food 🍽️

0150

The Coster lab 🧬🔬 @costerlab.bsky.social · 05/12/2024

🎉🎊 Happy to share that I have been awarded Tenure and academic promotion to Reader (=Associate Professor) at the ICR. Very grateful to all current and past lab members, as well as my supervisors and mentors along the years.

9411

The Coster lab 🧬🔬 @costerlab.bsky.social · 28/11/2024

Reached my last stop in Japan - Tokyo! Amazing views from the 450m-high Skytree tower with clear visibility to Mount Fuji over 100km away. Enjoying the contrast of tradition and order during the day, with the vibrant and non-stop nightlife.

140

The Coster lab 🧬🔬 @costerlab.bsky.social · 27/11/2024

Thank you so much for the invitation and for being an amazing host!

000

The Coster lab 🧬🔬 @costerlab.bsky.social · 24/11/2024

Beautiful red Japanese maples in Kyoto. Feeling very Zen...

0121

The Coster lab 🧬🔬 @costerlab.bsky.social · 24/11/2024

Yes! We've been using the exact same grease for years. Thumbs up for home-made phase-lock. It works 👍

030

The Coster lab 🧬🔬 @costerlab.bsky.social · 21/11/2024

Hi Tatiana, can you please add us. Thanks!

120

The Coster lab 🧬🔬 @costerlab.bsky.social · 20/11/2024

Really enjoying Japan so far. Surprised to see how popular Xmas is here! Including a massive display of various santas in Fukuoka...

020

The Coster lab 🧬🔬 @costerlab.bsky.social · 17/11/2024

Very excited - on my way to Fukuoka in Japan (first time), for the 3R+3C conference. Really looking forward to meeting old and new colleagues. Quite amusingly, saw a store at the Seoul airport called MCM. I'm sure I'll hear more about MCMs during the conference 😂

2130