The Lions, Colts, and Titans are all at around 50% against the spread, so there's roughly a 1 in 8 chance of this bet paying off. Sources below.
www.statmuse.com/nfl/ask/lion...
www.statmuse.com/nfl/ask/colts-against-the-spread-2025
www.statmuse.com/nfl/ask/titans-against-the-spread-2025