CADRC REC Scholar Dr. Nikhil Panicker secures a $2.1M NIH R35 grant to study how immune cells transfer damaged mitochondria and spread inflammation.

CADRC Neuroimaging Core Leader Dr. Mark Lowe and REC Scholar Dr. Benjamin Clayton present at the Spring 2026 NACC ADRC Meeting at the Loews Atlanta Hotel.

Celebrate Dr. Martha Sajatovic, CADRC Outreach Core Lead, recipient of the 2026 AAGP Distinguished Scientist Award for excellence in geriatric psychiatry research and mentorship.

YouTube video by Cleveland Alzheimer’s Disease Research Center

Graduate student Carly Rose to present CADRC Data Management and Statistics Core research on COVID-19, Shingrix, and Alzheimer’s disease risk at the 2026 Keystone Symposia in Germany.

With a new $6.2 million, five-year grant from the National Institute on Aging, researchers at Case Western Reserve University will use artificial i...

University Hospitals becomes the first host site for Howard University’s HU‑ERA‑PREP program. Meet Genesis Anderson, B.A., our newest coordinator helping to advance Alzheimer’s research and cultivate ...

The CADRC hosted its 2026 External Advisory Committee meeting to review research progress and strategic goals for Alzheimer’s and related dementia research.

New CADRC research led by Dr. Jagan Pillai identifies three distinct clinical subtypes in early-stage dementia by analyzing combined cognitive and behavioral symptoms.

A JAMA Neurology editorial by Dr. Brian Appleby and Dr. Mark Cohen evaluates claims of iatrogenic Alzheimer disease from historical growth hormone treatments, emphasizing that current medical practice...

What drives faster decline in dementia with Lewy bodies? New studies uncover key pathological and clinical factors, offering insights for better prognosis and clinical trial design.

The Cleveland Alzheimer’s Disease Research Center (CADRC) enhances its diagnostic capabilities with a new digital slide scanner. Learn how high-resolution digital imaging at the National Prion Disease...

Explore how neuropathology has served as the foundational "ground truth" for 40+ years of Alzheimer’s Disease Research Center (ADRC) discovery and how digital pathology is shaping the future of precis...

Understanding the mystery of the astrocyte: CADRC REC scholar Dr. Benjamin L.L. Clayton investigates new therapeutic targets for the rare genetic Alexander Disease.

Could CHCHD10 be the key to stopping Alzheimer’s? CADRC REC alumni Dr. Tian Liu launches NIA-funded research into tau aggregates and mitochondrial health.

For students at Case Western Reserve University, some of the best lessons stem from some of their hardest moments. That much is true for Anuj Pullakan...

Your Content Goes Here Your Content Goes Here Mapping the Brain: New Insights into Language-Based Alzheimer’s When we think of Alzheimer’s disease, memory loss is often the first symptom that comes to mind. However, for a subset of patients, the journey begins differently—with subtle, yet persistent, challenges in language. This specific presentation, known as logopenic primary progressive aphasia (LPA), is the focus of a new study recently published in the Journal of Alzheimer’s Disease by researchers at the Cleveland Clinic and the Cleveland Alzheimer’s Disease Research Center (CADRC).

Your Content Goes Here Your Content Goes Here Save Your Spot: Our Black History Month Brain Health Series Starts Next Week Join the Cleveland Alzheimer’s Disease Research Center next Thursday, February 5th as we kickoff our 5th Annual Black History Month Webinar Series! On the agenda: Pollution, Toxins, and the Brain: The Hidden Threats in Our Communities Learn how toxins, including lead, air pollution, and emissions from industrial plants or waste sites can affect cognitive function.

Your Content Goes Here Your Content Goes Here CADRC REC Scholar Awarded Grant to Study Mixed Dementia Biomarkers We are pleased to announce that CADRC REC Scholar, Carol Chan, MD, has been awarded a 3-year Clinician Scientist Research Development Grant from the Cleveland Clinic Neurological Institute. Dr. Chan serves as a geriatric psychiatrist at the Cleveland Clinic Center for Brain Health and is an Assistant Professor at the Cleveland Clinic Lerner College of Medicine.

Your Content Goes Here Your Content Goes Here In Case You Missed It: CADRC Researchers Find that Alzheimer’s Disease Can Be Reversed in Animal Models A CADRC-led study challenges the belief that Alzheimer’s brain damage is permanent. Researchers restored cellular energy in animal models using a compound called P7C3-A20, which not only stopped disease progression but reversed existing brain damage and fully restored memory and cognitive function.

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Your Content Goes Here Your Content Goes Here Driving Toward a Cure: A Heartfelt Thanks to Our Partners The Cleveland Alzheimer’s Disease Research Center (CADRC) is revving with gratitude! On Saturday, January 16, we celebrated a highly successful fundraising event brought to life by a fantastic partnership: Porsche Beachwood, the Northern Ohio Region Porsche Club of America (NORPCA), and WD Detailing.

Researchers have identified a brain protein whose absence leads to memory loss and Alzheimer’s-like damage in mice. Researchers at Johns Hopkins Medicine report that findings from a new study funded b...

BHA is a series of programs designed to promote healthy brain aging in older adults. It is made by the University of Kentucky SBCoA.

For generations, the medical world has operated under a sobering assumption: once Alzheimer’s disease takes hold, the damage to the brain is permanent. Research has traditionally focused on building "roadblocks" to slow the disease down, rather than finding a way to turn the car around. However, a transformative new study led by Kalyani Chaubey, PhD, in the laboratory of CADRC co-Investigator…

In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as:

Can moments of lucidity in Alzheimer’s reveal deeper insights into neurobiology? Our researchers are investigating cognitive fluctuations to improve diagnosis, monitoring and treatments. Learn about t...

In LBD, clumps of a protein called alpha-synuclein collect in several areas of the brain, such as:

CADRC Clinical Core Leader, Dr. Brian Appleby, and collaborating researchers from NEOMED have been awareded $40k by the UH-NEOMED Brain Health Intramural Funding program for a new pilot research project titled "Decoding Alzheimer’s Disease Mechanisms via Integrated Multi-Omics and O-GlcNAc Profiling." The Team and The Project The project is led by Principal Investigators Dr. Priya Raman, PhD (NEOMED)

Please join us in congratulating Dr. Diana Acosta Ingram, a Post-Doctoral Fellow in the Kraus Lab at Case Western Reserve University! She was just awarded a new 3-year research grant from the Alzheimer’s Association. The project will study the importance of neuronal cholesterol transport in Alzheimer’s Disease. Dr. Acosta Ingram will use advanced human brain cell organoid models to test outcomes of the APOE4/E4 risk allele.

Read the 2025 report to understand the burden of Alzheimer's and dementia on individuals, caregivers, government and the nation's health care system.

The Alzheimer's Association holiday gift guide offers gift ideas for dementia caregivers and individuals living in the early, middle and late stages of Alzheimer’s.

The Alzheimer’s Association Brain Health Habit Builder is a free online resource that helps you evaluate your current habits and create a personalized plan to support your brain health. Backed by research, it offers tailored insights to help you understand brain wellness, assess your routines, and receive evidence-based recommendations for making healthy, brain-protective changes. Learn more and get started at