Jaw-dropping patient videos and miraculous testimonials ignited a frenzy in China over a technique that aims to improve drainage from the brain. Now it is entering trials worldwide.

Transmissible tumors have been reported in a handful of animal species, but never before among fish. Is it possible in humans?

Molecular Psychiatry - Widespread synaptic density loss in schizophrenia follows molecular and network architecture

YouTube video by Carsten Korth

YouTube video by Carsten Korth

Science/AAAS peer-reviewed journals deliver impactful research, daily news, expert commentary, and career resources.

Müller-Schiffmann et al. identify oxidized MIF as a molecular hub relaying the effects of external stressors (e.g., infection with HSV-1) to cellular pathology associated with sporadic Alzheimer’s disease. Small-molecule compound PAV-174/ PAV-617 revert oxidized MIF and contingent tau phosphorylation and aggregation independent of viral infection in vitro and in vivo.

Müller-Schiffmann et al. identify oxidized MIF as a molecular hub relaying the effects of external stressors (e.g., infection with HSV-1) to cellular pathology associated with sporadic Alzheimer’s dis...

Müller-Schiffmann et al. identify oxidized MIF as a molecular hub relaying the effects of external stressors (e.g., infection with HSV-1) to cellular pathology associated with sporadic Alzheimer’s dis...

The authors found that the Alzheimer’s disease-associated protein tau, widely considered pathogenic when hyperphosphorylated, has a natural function as part of the innate immune system in the brain an...

Psilocybin reshapes brain networks through activity-dependent plasticity, including a weakening of recurrent cortical loops that could underlie its therapeutic effects.

Scientific Reports - Linking gut microbiota rhythmicity to circadian maturation in infants

The rise in artificial-intelligence technologies is unprecedented, but some predict a stock-market crash that could have knock-on effects for funding and jobs.

Proteomics of laser-dissected lipofuscin from aged, healthy brains reveals Palmitoyl-Protein Thioesterase 1 (PPT1) and other CLN proteins as constituents. PPT1 is increasingly sequestered to lipo...

H9N2 is currently the second most common avian influenza A virus subtype infecting humans. Monitoring viral phenotypic and genotypic adaptation to humans is crucial for risk assessment. Here, we co...

Social deficits are a hallmark of schizophrenia, often characterized by impairments in processing and integrating socially transmitted information. However, translational models that accurately captur...

Human-targeted drugs alter the composition and function of the gut microbiome, but their effect on the risk of gastrointestinal infection has received little attention. In two studies, Grieβhammer et ...

Social deficits are a hallmark of schizophrenia, often characterized by impairments in processing and integrating socially transmitted information. However, translational models that accurately captur...

Social deficits are a hallmark of schizophrenia, often characterized by impairments in processing and integrating socially transmitted information. However, translational models that accurately captur...

America’s run as the premier techno-superpower may be over.

YouTube video by Kieron Middleton

The Max Planck Society is good at attracting international postdocs but struggles to retain them, survey finds.

Translational Psychiatry - Association of viral RNAs in the choroid plexus with bipolar disorder and schizophrenia and evidence for the hepatitis C virus involvement in neuropathology

IntroductionConsciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. Within this framework, the thalamus...

Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

SARS-CoV-2 induces amyloid-β pathology in the central nervous system.

Für die Beitragsserie „Forschung vordenken für 2035“ in den table.briefings research skizzierte ich meine Vision für die wissenschaftspolitische Welt der Zukunft in Form der fiktiven TV-Serie „Rese…

npj Aging - Psilocybin treatment extends cellular lifespan and improves survival of aged mice

Within the concept of the extended mind, the active modification of external objects, externalizations, is seen as an auxiliary means to adapt to the environment. Toolmaking and use are advanced stage...