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GLP-1R–GIPR–PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice - Nature
GLP-1–GIP–lanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPARα, PPARγ and PPARδ, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse model...