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Christine He

@christinehe.bsky.social
141 followers 241 following 6 posts

Bioinformatics and data science at Ansa Biotechnologies 🧬

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Reposted by Christine He
Michael Hall @mbhall88.bsky.social · 15/06/2026
For anyone doing ONT Microbial Genomics, please take 1 minute (less?) to tell us which assembly metrics you care most about when evaluating whether an assembly is "good". We are doing a benchmark of different QC tools (barcode/adapter trimming and QC filtering). microbial-qc-survey.streamlit.app
microbial-qc-survey.streamlit.app
Microbial QC Survey
A standalone Streamlit app that collects community priority weights over fourassembly-QC metrics ...
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Reposted by Christine He
Vivek Mutalik @vivekmutalik.bsky.social · 08/06/2026
Rapid diagnosis of common, undetected, and uncultivable bloodstream infections from positive blood cultures using Oxford Nanopore sequencing: a metagenomic pipeline analysis - The Lancet Microbe www.thelancet.com/journals/lan... #microsky
thelancet.com
Rapid diagnosis of common, undetected, and uncultivable bloodstream infections from positive blood cultures using Oxford Nanopore sequencing: a metagenomic pipeline analysis
These findings show that metagenomic sequencing has the potential to rapidly and comprehensively detect pathogens and AMR in bloodstream infections. Integration into clinical practice could help to cl...
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Christine He @christinehe.bsky.social · 29/05/2026
Come to ONT's industry event at ASM to hear about two exciting new tools from @jimshaw.bsky.social! SNPmers (polymorphic kmers) are leveraged for impressive performance in both myloasm (metagenomic assembly) and savont (16S ASVs). Registration link 👇
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Reposted by Christine He
Gaëtan Benoit @gaetanbenoit.bsky.social · 11/05/2026
Note that I released a new version of metaMDBG (v1.4) last week focusing on scalability. You can now process such dataset in 6 days and 130 GB of memory
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Christine He @christinehe.bsky.social · 02/05/2026
Released today: ~1.5 Tbp of ONT metagenomic sequencing from compost. Assembly, MAGs, and downstream analysis are available to play with epi2me.nanoporetech.com/compost_mgx_...
epi2me.nanoporetech.com
Metagenomic Assembly Sheds Light on Microbial Diversity in Compost
Overview We are pleased to release a metagenomic dataset from deep sequencing of a mature compost…
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Christine He @christinehe.bsky.social · 27/08/2025
ONT has a temporary bioinformatics position (8 months) open while I'm on maternity leave. Focus will be on microbial genomics but with opportunities to work on projects across the breadth of genomics! ejnh.fa.em2.oraclecloud.com/hcmUI/Candid...
ejnh.fa.em2.oraclecloud.com
Applications Bioinformatician (8 month temporary role)
We are looking for an individual with expertise in bioinformatics and data analysis, specializing in microbial genomics and metagenomics, to join our Applications team as an Applications Bioinformatic...
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Christine He @christinehe.bsky.social · 17/07/2025
An ONT webinar where I discuss wet and dry lab methods for environmental metagenomics, as well as analysis of 1.5 Tb (!!) of metagenomic sequencing from compost. Featuring the nanoMDBG assembler, strain-dependent AMR profiles, and invertons: www.youtube.com/watch?v=OZ4P...
youtube.com
Exploring Oxford Nanopore sequencing methods for environmental samples
YouTube video by Oxford Nanopore Technologies
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Christine He @christinehe.bsky.social · 21/01/2025
Our guide for best practices in metagenomic assembly and binning of @nanoporetech.com data, highlighting some exciting recently developed tools for high accuracy long reads
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Reposted by Christine He
Austin Richardson @agdr.org · 13/12/2024
NCBI's Taxonomy changes over time. We built Taxonomy Time Machine to track these changes: 🕰️ app: taxonomy.onecodex.com 📄 pre-print: www.biorxiv.org/content/10.1...
A screenshot of a webpage titled "Taxonomy Time Machine" showing the taxonomic lineage and descendants of the Influenza A Virus
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