Reposted by Christian Preußer
EVs facilitate cell communication, but does this explain their release?
Our new #JEV Perspective begins with thermodynamics and explores when the #EV function becomes quantitatively plausible.
It's a challenging idea to develop, and one I’m especially proud of.
doi.org/10.1002/jev2...
doi.org
Extracellular Vesicle Release Within Energetic and Quantitative Constraints: Implications for Function
Extracellular vesicle release reflects a thermodynamic membrane baseline in cells maintained far from equilibrium. Cargo loading follows stochastic partitioning, so most vesicles contribute to flux w...
