iiinova — where your digital self keeps evolving

charlesvorkas.bsky.social

@charlesvorkas.bsky.social

Reposted by @charlesvorkas.bsky.social

The Journal of Immunology @jimmunol.bsky.social · 19/01/2026

Data indicate that human CD4+ mucosal-associated invariant T cell TCRs may be selected by alternative MR1 ligands in addition to canonical riboflavin intermediates. Find this #TopRead article from @charlesvorkas.bsky.social and team online: ow.ly/hcNc50XYarT.

033

charlesvorkas.bsky.social @charlesvorkas.bsky.social · 13/11/2025

We are pleased to share our new publication linking TRAV1-2 negative MAIT cells, CD4 coexpression, and tuberculosis. A conserved innate-like T cell subset with more TCR diversity than previously appreciated. academic.oup.com/jimmunol/adv... #Immunology #maitcells #TCRdiversity

academic.oup.com

CD4+ mucosal-associated invariant T cells express highly diverse T cell receptors

Abstract. Mucosal-associated invariant T (MAIT) cells are highly conserved innate-like T cells in mammals recognized for their high baseline frequency in h

000

charlesvorkas.bsky.social @charlesvorkas.bsky.social · 02/05/2025

Thank you @bsheridanlab.bsky.social. We are excited about sharing this work, particularly in light of parallel findings in IV BCG vaccination models in macaques that demonstrate CD8aa+ lymphocytes are critical for controlling Mtb. Can NK cells recognize specific MHC I-epitope complexes? TBD

010