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Chronic Diseases and Translational Medicine (CDTM)

@cdtm2015.bsky.social
2 followers 3 following 18 posts

Focused on chronic diseases and related translational research. Indexed in Scopus, PubMed, PMC, Embase, DOAJ. CiteScore 2023: 6.7, Rank #60/636 🔗 onlinelibrary.wiley.com/journal/258…

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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 08/10/2026
❤️📊 New Research: Social determinants of health, age, and sex enabled good classification of prevalent cardiovascular disease using LASSO and XGBoost models. 🔗 doi.org/10.1002/cdt3... #CardiovascularDisease #SDOH #MachineLearning @wileyhealth.bsky.social @wileylifesci.bsky.social
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 08/09/2026
⚖️🩺 New Research: Higher BMI predicted treated hypertension in Australian men, with obesity showing the strongest relative effect in men aged 30–44 years. 🔗 doi.org/10.1002/cdt3... #Hypertension #Obesity #MensHealth @wileyhealth.bsky.social @wileylifesci.bsky.social
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Baseline Body Mass Index Category and Incident Treated Hypertension in Australian Men: A Linked Prospective Cohort Study Using PBS/MBS Data
Kaplan–Meier hypertension-free survival by baseline body mass index category, primary adult cohort (men aged ≥ 18 years, n = 12,742). Time since baseline in years is plotted on the horizontal axis an...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 01/09/2026
🫁✨ New Systematic Review: Durvalumab plus tremelimumab improved survival in metastatic NSCLC with PD-L1 <1%, with fewer treatment-related adverse events than chemotherapy. 🔗 doi.org/10.1002/cdt3... #LungCancer #NSCLC #Immunotherapy @wileyhealth.bsky.social @wileylifesci.bsky.social
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Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
PRISMA 2020 flow diagram of included studies.
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 27/08/2026
🧠 New Research: Stroke rehabilitation improved physical function, balance, and quality of life, but patients remained below population norms after rehabilitation💪. 🔗 doi.org/10.1002/cdt3... #Stroke #Rehabilitation #QualityOfLife @wileyhealth.bsky.social @wileylifesci.bsky.social
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Rehabilitation After Stroke in a Transition From Hospital to Municipality—Impact of Amount of Rehabilitation
Measurements obtained throughout the study, from acute hospitalization to the end of rehabilitation in the municipalities. The intervals between assessments are approximate. The lower boxes indicate ...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 17/08/2026
🧠 New Research: Severe OSA was linked to higher plasma total Tau and lower MMSE performance, with intermittent hypoxia and sleep fragmentation showing the strongest associations. 🔗 doi.org/10.1002/cdt3... #SleepApnea #Cognition #Tau @wileyhealth.bsky.social @wileylifesci.bsky.social
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Associations of Plasma Total Tau Level and MMSE Score With Polysomnographic Data in Middle‐Aged Men With Severe Obstructive Sleep Apnea: A Pilot Study
Background Obstructive sleep apnea (OSA) is one of the most common sleep disorders. Intermittent nocturnal hypoxia and sleep fragmentation in OSA may be among the main mechanisms triggering cognitiv...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 21/07/2026
💉🔍New Review: GLP-1 receptor agonists increase retained gastric contents during endoscopy, but aspiration risk remains low. Guidance favors risk-based management over routine drug cessation. 🔗 doi.org/10.1002/cdt3... #GLP1 #Endoscopy #PatientSafety @wileyhealth.bsky.social @wileylifesci.bsky.social
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GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance
Pharmacological mechanisms and physiologic effects of GLP-1 receptor agonists relevant to peri-endoscopic risk.
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 14/07/2026
🚀New Perspective: Brazil’s adoption of robot-assisted prostatectomy shows how surgical innovation can promote equity and population health 🌏🤖. 🔗 doi.org/10.1002/cdt3... #RoboticSurgery #ProstateCancer #HealthEquity @wileyhealth.bsky.social @wileylifesci.bsky.social
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From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System
Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real-world platform for integrating prevention, diagn...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 06/07/2026
🧪✨New Research: Plasma exosome metabolomics revealed stage-specific changes in elderly women with pre-MetS and MetS, highlighting candidate exosomal biomarkers. 💡🩺 🔗 doi.org/10.1002/cdt3... #MetabolicSyndrome #Exosomes @wileyhealth.bsky.social @wileylifesci.bsky.social
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Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overla...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 28/06/2026
✨New Report: CGM-supported remote monitoring after hospital discharge was feasible, well accepted, and helpful in guiding telehealth glycemic management in higher-risk diabetes populations🏥. 🔗 doi.org/10.1002/cdt3... #Diabetes #CGM #Telehealth @wileyhealth.bsky.social @wileylifesci.bsky.social
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Discharge Remote Monitoring Systems for Glycemic Management After Hospital Discharge
Heat map of median number of telehealth interactions by subgroup and theme. Major themes identified included intervention after remote monitoring alerts (e.g., “Team reached out to participant and in...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 20/06/2026
🧬New Research: Single-cell profiling of gastric cancer metastasis identified NAP1L1 as a conserved driver of epithelial reprogramming, alongside distinct immune remodeling. 🔗 doi.org/10.1002/cdt3... #GastricCancer #SingleCell #TumorMicroenvironment @wileyhealth.bsky.social @wileylifesci.bsky.social
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Landscape of Immune Remodeling and NAP1L1‐Driven Epithelial Reprogramming in Gastric Cancer Metastasis
High-resolution single-cell atlas of normal gastric tissue, primary gastric cancer, and metastatic lesions. (A) Schematic diagram of experimental design. (B) Bar plot for qualified cell numbers in ea...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 09/06/2026
📊New Research: Multimorbidity increased ADL and IADL disability in older adults in Ireland👵, with earlier IADL impairment and worse functional decline linked to depression and age📉. 🔗 doi.org/10.1002/cdt3... #Multimorbidity #Aging #PublicHealth @wileyhealth.bsky.social @wileylifesci.bsky.social
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Effect of Chronic Noncommunicable Diseases Multimorbidity on Functional Disability in Older Adults in Ireland: Evidence From the 2019 Irish Health Survey
Prevalence (%) of different morbidities in the Irish Health Survey 2019. Note: Asthma, bronchitis (chronic bronchitis or chronic obstructive pulmonary disease or emphysema), heart attack (heart attac...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 01/06/2026
🧬New Research:Single-cell profiling revealed distinct immune hallmarks in untreated colorectal cancer liver metastases, including enriched CXCL13+ CD4 T cells, Tregs, SPP1+ macrophages, and IGFBP7+ CAFs. 🔗 doi.org/10.1002/cdt3... #ColorectalCancer #SingleCell @wileyhealth.bsky.social
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 26/05/2026
🫀 New Research: Nearly one-third of Indian adults aged ≥40 had a ≥10% 10-year CVD risk, with alcohol use, hypertension, and social vulnerability linked to higher risk. 🔗 doi.org/10.1002/cdt3... #CardiovascularRisk #India #PublicHealth @wileyhealth.bsky.social @wileylifesci.bsky.social
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 17/05/2026
🔍 New Research: A stacked multi-label model accurately predicted co-occurring microvascular and macrovascular complications in type 2 diabetes, with distinct risk profiles revealed by SHAP analysis. 🔗 doi.org/10.1002/cdt3... #Type2Diabetes #MachineLearning @wileyhealth.bsky.social
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A Stacked Ensemble Multi‐Label Model for Predicting Co‐Occurring Microvascular and Macrovascular Complications in Type 2 Diabetes
Feature importance for predicting multiple diabetes complications based on a Stacking-Classifier Chain model.
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 10/05/2026
🌏New Perspective: Chronic diseases remain a major public health challenge in Australia, with Tasmania bearing a disproportionate burden shaped by ageing, disadvantage, and modifiable risk factors. 🔗 doi.org/10.1002/cdt3... #ChronicDisease #PublicHealth #Epidemiology @wileyhealth.bsky.social
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The Epidemiological Landscape and Burden of Chronic Disease in Australia: Contextualizing the Distinct Profile of Tasmania
Chronic diseases are the leading causes of morbidity and mortality worldwide and impose a substantial and long-lasting burden on individuals, families, communities, and healthcare systems. In Austral...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 01/05/2026
💉 New Review: GLP-1 receptor agonists are emerging as dual liver–heart therapies in MASLD, improving steatohepatitis and fibrosis while reducing major cardiovascular events🫀. 🔗 doi.org/10.1002/cdt3... #MASLD #GLP1 #CardiometabolicHealth @wileyhealth.bsky.social
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GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes
Endogenous GLP-1 and exogenous GLP-1 RAs activate GLP-1R-expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic c...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 23/04/2026
🫀New Systematic Review: Frailty was linked to cardiovascular events mainly in overweight/obese individuals, suggesting body composition and metabolic profile may shape cardiovascular risk in frailty. 🔗 doi.org/10.1002/cdt3... #Frailty #CardiovascularDisease #Obesity @wileyhealth.bsky.social
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Frailty and Cardiovascular Events as Determined by Body Composition: A Systematic Review
Frailty phenotypes and risk of cardiovascular disease. Sarcopenic obese phenotype is associated with increased prevalence of cardiovascular risk factors and progression of metabolic syndrome, leading...
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Chronic Diseases and Translational Medicine (CDTM) @cdtm2015.bsky.social · 13/04/2026
📰New Report:Adding symptom frequency and severity improved machine-learning accuracy for Long COVID classification, outperforming occurrence-only models and better distinguishing meaningful illness. 🔗 doi.org/10.1002/cdt3... #LongCOVID #MachineLearning #Epidemiology @wileyhealth.bsky.social
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A Research Classification for Long COVID: Symptom Frequency and Severity Improve Accuracy of Machine Learning Models
Click on the article title to read more.
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