Reposted by Caroline Watson
Just in time for thanksgiving our paper is out ☄️
using fluctuating methylation clocks as barcodes we show that the variation in the hematopoietic stem cell pool that (in most of us) leads to clonal hematopoiesis in later life is likely present *before birth*
👉🏼 www.nature.com/articles/s41...
nature.com
Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life - Nature Communications
Clonal hematopoiesis becomes increasingly common with age. Here the authors track stem cell dynamics in monozygotic twins and provide evidence that clonal hematopoiesis in later life reflects weak sel...
