iiinova — where your digital self keeps evolving

Reposted by Carmen Li

Amir Mitchell @amitchell.bsky.social · 06/08/2026

Our recent mBio paper (3rd paper for @carmenli.bsky.social 🥂). We mapped evo resistance adaptations in 40 antibiotic + non-antibiotic drugs to evaluate the risk of multi-drug resistance (in vitro) ... we're now studying this in vivo (more to come). 🦠🧪 journals.asm.org/doi/10.1128/...

Genomic position of adaptive mutations identified in E. coli strains adapted against 40 antibiotic and non antibiotic drug in vitro. Repeated mutations in regulator of the acrA/B efflux pump are common to multi-drug resistant strains.

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Reposted by Carmen Li

Bioinformatics Advances @bioinfoadv.bsky.social · 04/03/2026

🧫 Just out in Bioinformatics Advances: "AssiST: Convolutional neural network for analysis of antibiotic susceptibility testing" Read the full paper here: doi.org/10.1093/bioadv/vbag063 Authors include: @carmenli.bsky.social, @amitchell.bsky.social

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Reposted by Carmen Li

Amir Mitchell @amitchell.bsky.social · 22/12/2025

Our recent paper in npj Antimicrobials and Resistance is a great example of scientific serendipity: after staring at thousands of bacterial growth curves over many studies, we started wondering whether the curve shapes themselves carry mechanistic information 1/9 🦠🧪 www.nature.com/articles/s44...

nature.com

Predicting drug inactivation by changes in bacterial growth dynamics - npj Antimicrobials and Resistance

npj Antimicrobials and Resistance - Predicting drug inactivation by changes in bacterial growth dynamics

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