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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 05/10/2026

🐭 Low-THC, CBD-rich hemp oil boosted sociability in mice — no sedation, no side effects. An early lead for conditions like autism. doi.org/10.1089/can....

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 30/09/2026

⚖️ Could cannabis compounds help treat obesity? This review makes the mechanistic case: obesity involves chronic inflammation, and THCV, THC, and CBD have anti-inflammatory and metabolic effects. Cannabis users also tend to have lower BMI. doi.org/10.1089/can....

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 30/09/2026

🐀 CBD cut alcohol intake by ~50% in alcohol-preferring rats — without affecting chocolate seeking, so it's not sedation. May work by easing the anxiety that drives drinking. A preclinical lead for anxiety + AUD. doi.org/10.1089/can....

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 28/09/2026

🌍 In 2020, Lebanon became the first Arab country to legalize medical cannabis — driven by economics ($1B/year in projected exports), not public health. The law is export-only, excludes traditional farmers, and psychiatrists warned it skipped proper consultation. doi.org/10.1089/can....

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 23/09/2026

📉 Who needs high-dose cannabis for chronic low back pain? A new 4-factor score predicts it with solid accuracy (AUC 0.80) — and high-dose users saw the most pain relief. Bonus: 93% of baseline opioid users quit by year 5. 🌿 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 21/09/2026

📣 Marc (hah) your calendars! The MACRC 2026 Annual Conference is headed to Philadelphia, November 6–8, 2026! This year's theme = "New Frontiers in Cannabinoid Science" 🔗 Learn more & register: www.m-acrc.org

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 16/09/2026

📣 MACRC 2026 Annual Conference: "New Frontiers in Cannabinoid Science." Philadelphia, Nov 6-8, 2026. Cannabinoids in women's health, GI, metabolic disease, infection, and cancer, plus policy and public health. Registration and abstract submission now open. 🌿 www.m-acrc.org

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 14/09/2026

📢 Call for papers: Cannabis & Cannabinoid Research special issue on minor cannabinoids (CBG, CBN, THCV, CBDV, acidic + semisynthetic). Mechanisms, PK, chemistry, safety, policy. Deadline April 30, 2027. Select the special issue in ScholarOne. 🧪 journals.sagepub.com/page/ccb/cal...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 07/09/2026

🧪 How to store cannabinoids so they don't degrade: Room temperature turns THC into CBN. CBD-only products hold up fine on the shelf, but THC-rich ones need the cold. Most stable option for THC: an ethanol solution kept at −20°C. Storage should match the product. doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 07/09/2026

🔬 Do cannabis "cured my cancer" stories hold up? Researchers tried to verify them against medical records. Of 97 patients who reported a benefit, only 15 had reviewable data, and just 1 case met the bar for strong evidence. doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 02/09/2026

👵 12.1% of US adults 50–80 used cannabis in the past year, and 34.2% of them used 4+ days/week. Use skewed toward unpartnered, unemployed, and drinking respondents. That's frequent use in an age group with polypharmacy, fall risk, and thin evidence. journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 31/08/2026

🐟 CB1 agonist cut aggression and brain oxidative stress in zebrafish. After 24h isolation, ACEA-treated fish struck and bit less than controls or AM-251 fish, with lower malondialdehyde and higher sulfhydryl in dominants and subordinates alike. journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 26/08/2026

🧪 Cannabis self-report doesn't hold up in psychosis. 38% with a positive urine or hair test denied use in the past 90 days (CATIE); 70% denied it in a forensic sample. The authors argue for creatinine-corrected urine THC-COOH as an objective standard. journals.sagepub.com/doi/full/10....

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 24/08/2026

🧠 Medical cannabis for non-motor symptoms in Parkinson's: 3-month open-label cohort, 50 completers. Improvements in overall NMS burden, sleep, pain, and quality of life. Nighttime urinary frequency also dropped, while daytime measures held steady. journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 19/08/2026

📊 Cannabis research mapped: 10,577 articles across 7 databases. Most from the US, UK, and Canada; peak in 2021. Top journals lean addiction and toxicology, but neuroscience was just 1.6% of the literature. The mechanistic work is the gap. journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 17/08/2026

🌱 Cannabis roots: the discarded part of the plant, reviewed. Roots carry triterpenes, sterols, alkaloids, and phenolic amides, with preclinical anti-inflammatory and analgesic signals. Cannabinoid content is minimal. journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 12/08/2026

🧴 Topical CBD for fibromyalgia: 12-week single-arm pilot, 30 women. Localized pain down by week 4 and held at week 12 (60% hit MCID). Function improved. Full adherence, no adverse events. No change in fatigue, anxiety, or depression. No control arm; RCT needed. journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 10/08/2026

🎧 Cannabis + music: survey of 122 users. Most rated the combo positively: more relaxation, better mood, more connection. Many also used cannabis to substitute for meds for pain, anxiety, and sleep, with music amplifying the effect. journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 05/08/2026

🧭 Oldie but goodie: 2024 review on the endocannabinoid system & axon guidance. Across animal models, disrupting CB1, CB2, GPR55, or eCB metabolism causes axon pathfinding errors. Developing axons are sensitive to cannabinoids: a frame for prenatal exposure work. journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 03/08/2026

🧬 New RCT (n=24): oral THC:CBD eased fibromyalgia symptoms but left plasma NAEs (PEA, OEA, SEA) flat over 16 weeks, with near-zero effect sizes. Takeaway: blood NAEs may not track cannabis response here. The mechanism looks central, not peripheral. 📄 journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 29/07/2026

Medical cannabis is legal in 47 states, but contaminant testing standards vary widely. A new review covers testing for heavy metals, pesticides, mycotoxins, and residual solvents. The science is there. The harmonization isn't. 🌿⚗️ Link: journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 27/07/2026

Topical/transdermal CBD is everywhere, but the clinical evidence is thin and poorly designed. A systematic review in Cannabis & Cannabinoid Research found just 8 qualifying studies out of 544, all with high risk of bias. The market is way ahead of the science. 🌿⚗️ journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 22/07/2026

"Fast-acting" cannabis edibles actually live up to the name — new PK data show THC peaks ~30 min earlier than standard edibles. Same Cmax and AUC though, so the total exposure is identical. Useful for dose timing; doesn't solve overconsumption. 🌿📊 Link: journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 20/07/2026

THC suppressed BDNF gene expression in the adolescent mouse hippocampus — but co-administration with CBD prevented it. A reminder that what's in the product matters as much as whether cannabis is used at all. Sex differences observed too. 🧠🌿 Link: journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 15/07/2026

HPLC is the gold standard for cannabinoid quantification — but slow and costly. A new study tests A-TEEM spectroscopy + machine learning as a faster alternative, hitting R² = 0.994 across 14 cannabinoids. One to watch for high-throughput work. 🌿🔬 journals.sagepub.com/doi/abs/10.1...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 13/07/2026

First longitudinal PET imaging of CB1 receptors in a neuroHIV mouse model — and it got complicated fast. The induction agent (DOX) altered CB1R expression itself, muddying Tat's effects. A reminder: your model's tools can be your confounds. 🧠🔬 journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 08/07/2026

Extraction method shapes everything about a cannabis extract. A new review in Cannabis & Cannabinoid Research breaks down how solvent, temperature, pressure, and time affect the final chemical profile. 🌿🔬 journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 06/07/2026

Doctor-recommended cannabis use in California dropped by more than half from 2019–2024, while overall use stayed flat. Legalization didn't reduce use—it just moved people out of the medical system. Who's watching out for patients with complex conditions? 📋🌿 journals.sagepub.com/doi/10.1177/...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 01/07/2026

New research: Self-titrated medical cannabis improved pain, sleep, and nighttime urinary frequency in Parkinson's patients over 3 months. No correlation found between THC:CBD ratio & outcomes. Open-label, but promising signal for an underserved symptom cluster. RCTs needed 🧠

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 29/06/2026

💧 Measuring endocannabinoids in saliva could revolutionize research — non-invasive, stress-free, and responds to physiological challenges. But we still don't fully understand how endocannabinoids get into saliva. More mechanistic work needed. 📄 doi.org/10.1177/2578... #Endocannabinoid #Biomarkers

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 24/06/2026

🧠 HIV viral protein alters CB1 cannabinoid receptors in region-specific ways—but PET imaging may miss subtle chronic changes that Western blot detects. Multiple methods needed to capture the full picture of endocannabinoid system changes in HIV. 📄 doi.org/10.1177/2578... #HAND #Endocannabinoid #HIV

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 22/06/2026

⚖️ Cannabis rescheduling to Schedule III ≠ federal legalization. New analysis: it would expand research access and provide tax relief, but wouldn't legalize dispensaries, allow interstate commerce, or expunge records. A significant shift — not a green light. 📄 doi.org/10.1177/2578... #CannabisPolicy

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 17/06/2026

🧬 CB2 cannabinoid agonist reliably suppresses evoked pain in nerve injury model — but translating spontaneous pain from animals to humans remains a challenge. Robust preclinical efficacy, yet the drug failed in clinical trials. Better models needed. 📄 doi.org/10.1177/2578... #PainResearch

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 15/06/2026

📊 Cannabis use disorder prevalence estimates range from 0.06% to 76.9% in health data — not because rates vary that much, but because everyone defines it differently. Systematic review finds no validated case definitions exist. Standardization needed. 📄 doi.org/10.1177/2578... #CannabisUseDisorder

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 10/06/2026

🔬 Cannabis safety testing methods are reliable — but state-by-state regulatory inconsistency undermines consumer protection. New review calls for harmonized national standards for contaminant testing across the expanding legal market. 📄 doi.org/10.1177/2578... #Cannabis #PublicHealth #Regulation

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Subscription and open access journals from Sage, the world's leading independent academic publisher.

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 08/06/2026

🍫 Fast-acting cannabis edibles peak 30 minutes earlier than standard products — potentially reducing overdose risk from delayed onset. Microencapsulation technology delivers faster absorption without changing total THC exposure. 📄 doi.org/10.1177/2578... #Cannabis #Edibles #Research

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 08/06/2026

🧠 The brain has its own immune cells—and they may hold the key to understanding addiction. Science at the Source Ep. 6 is out! Dr. Hilary Marusak talks microglia, adolescent brain development, and drug exposure with neuroimmunologist Maricela Martinez. 🎥 www.youtube.com/watch?v=koYL... @uci_cannabis

youtube.com

Microglia in Addiction & Early Career Development w/ Marcielo Martinez | Science at the Source Ep. 6

Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Maricela Martinez, PhD student and rising star in neuroimmunology, to explore the groundbreaking connections between…

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 03/06/2026

🧬 CB2 cannabinoid receptors reduce brain inflammation in graft versus host disease — but surprisingly don't prevent behavioral symptoms. Inflammation and behavior may need separate treatment strategies. 📄 doi.org/10.1177/2578... #GVHD #Neuroscience #Cannabinoid

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 01/06/2026

🔬 New method quantifies 14 cannabinoids in minutes with 99.4% accuracy — matching traditional lab testing at a fraction of the cost. A-TEEM spectroscopy + machine learning could transform cannabis quality control. 📄 doi.org/10.1177/2578... #Cannabis #Cannabinoids #Research

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 27/05/2026

🔬 Cannabis and inflammation in people with HIV — it's complicated. New study finds lower general inflammation (CRP), but higher cardiovascular risk marker (sCD14). One step forward, one step sideways. 📄 doi.org/10.1177/2578... #HIV #Cannabis #Inflammation #PublicHealth #CardiovascularRisk

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 25/05/2026

🧬 Low-dose CBD was safe and well tolerated in virally suppressed adults with HIV — may have reduced resting heart rate in men by ~8 bpm. New RCT finds no disruption to viral suppression, liver function, or immune markers. Safety signal is encouraging. 📄 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 20/05/2026

💊 A cannabinoid that failed a clinical trial reliably suppresses nerve pain in rats — but whether it relieves spontaneous, ongoing pain remains unclear. New research highlights how preclinical pain studies can measure the wrong thing. 📄 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 18/05/2026

📊 How common is cannabis use disorder? Researchers aren't sure — because nobody's measuring it the same way. Review of 56 studies finds prevalence estimates ranging from 0.06-76.9%, with no study validating its case definition against a gold standard. 📄 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 13/05/2026

⚗️ Cannabis is legal in half the U.S., but safety testing is a patchwork. Each state sets different limits for heavy metals, pesticides, and contaminants. Consumer protection varies by zip code. Researchers call for national standards before markets outpace oversight. 📄 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 11/05/2026

🍬 Fast-acting cannabis edibles hit peak THC in 30 min vs. 60 for standard ones — same total dose, faster onset. Could reduce accidental overdoses from impatient users, but raises new questions about impairment timing and safety labeling. 📄 doi.org/10.1177/2578...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 06/05/2026

🧠 Bone marrow transplant patients develop brain inflammation — but fixing it doesn't fix behavior. Deleting the CB2 receptor reduces neuroinflammation in GVHD mice, yet lethargy and stress responses remain. The culprit may be circulating cytokines, not the brain itself. 📄 doi.org/10.1177/2578...

doi.org

Role of Cannabinoid Receptor Type 2 in Acute Behavioral Responses to Graft Versus Host Disease in Male Mice - Alison Moe, Hannah A. Liphart, Kathryn Heaster, Julian Romero, William R. Drobyski, Cecilia J. Hillard, 2026

Introduction: Graft versus host disease (GVHD) is a debilitating consequence of bone marrow (BM) transplantation for the treatment of hematological cancers and ...

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 04/05/2026

🌱 The 36th Annual ICRS Symposium is headed to Dijon, France 🇫🇷 — June 28–July 2, 2026! A can't-miss for cannabinoid and endocannabinoid researchers at every stage. Registration and abstracts are open! icrs.com/annual-icrs-symposium 🌿 #ICRS2026 #cannabinoidresearch

icrs.com

Annual Symposium landing page

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 29/04/2026

🚗 Older adults are using more cannabis — and getting behind the wheel. Aging amplifies THC impairment through slower metabolism and declining cognition, yet this group is almost entirely absent from crash risk research. A serious gap for a serious risk. 📄 doi.org/10.1177/25785125251410814 #Cannabis

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 27/04/2026

🧪 That CBD on the shelf? It can be converted to THC — and often is. A new review breaks down how acid catalysis turns CBD into Δ8- & Δ9-THC, fueling a flood of unregulated products with uncertain safety. The fix? Better chemistry, tighter controls. 📄 doi.org/10.1089/can.2025.0015 #Cannabinoids #CBD

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Cannabis and Cannabinoid Research @cannabisjrnl.bsky.social · 22/04/2026

🩹 Cannabis for diabetic nerve pain: promising, but don't get too excited. A systematic review of RCTs found pain relief in 3 of 4 trials — but only 4 small, high-bias studies qualified. Too early for firm recommendations. 📄 doi.org/10.1177/2578... #DiabeticNeuropathy #MedicalCannabis #ChronicPain

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Subscription and open access journals from Sage, the world's leading independent academic publisher.

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