Reposted by Candice Chapouly
Repost
[Publication] Happy to share @candicechaps.bsky.social and Dr Mora latest publication in @biomedcentral.bsky.social. They demonstrate that Dll4-Notch1 pathway controls astrogliosis in neuroinflammatory context such as MS. jneuroinflammation.biomedcentral.com/articles/10....
jneuroinflammation.biomedcentral.com
Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis - Journal of Neuroinflammation
Under neuroinflammatory conditions, astrocytes acquire a reactive phenotype that drives acute inflammatory injury as well as chronic neurodegeneration. We hypothesized that astrocytic Delta-like 4 (DL...