Circadian rhythms are endogenous ~24 h oscillations that regulate daily changes in neural activity, metabolism, and behavior. Disruption of circadian rhythms is a hallmark of neurological and psychiat...

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Parkinson's disease (PD) is a classic neurodegenerative disorder characterized by both motor and nonmotor symptoms, with circadian rhythm disruption being particularly prominent. This disruption leads...

Harmsen et al. compared the metabolic impact of natural daylight vs. artificial office lighting in individuals with type 2 diabetes over 5 days. Daylight improved glucose homeostasis, whole-body fat u...

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The circadian system regulates daily rhythms in metabolism and hormone secretion; however, in type 2 diabetes, disrupted clock gene oscillations in skeletal muscle impair metabolic regulation. Insulin...

Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain’s ...

BACKGROUND: Time-restricted eating has gained attention for its potential cardiometabolic health benefits. Existing time-restricted eating approaches may have limited adherence and sustainability due ...

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Get more from Bill Lagakos on Patreon

Get more from Bill Lagakos on Patreon

Get more from Bill Lagakos on Patreon

Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain’s ...

BackgroundAutism spectrum disorder (ASD), a neurodevelopmental condition strongly associated with PTEN mutations, demonstrates limited responsiveness to curr...

10.1542/6383520259112Video AbstractPEDS-VA_2025-0729416383520259112OBJECTIVES. Given concerns regarding health implications of adolescent smartphone use, we tested associations of smartphone ownership...

Editor’s Note: Dr. Eli Cahan is a former editor of the Section on Pediatric Trainees (SOPT) feature in Pediatrics, and an investigative journalist who covers child welfare. He is also a neonatology fe...

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