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Michael Calderwood

@calderwoodmd.bsky.social
1.6K followers 1.1K following 63 posts

Infectious Diseases Physician, Chief Quality Officer at Dartmouth Hitchcock Medical Center, Associate Professor at Dartmouth’s Geisel School of Medicine

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Michael Calderwood @calderwoodmd.bsky.social · 07/09/2025
Your intestinal microbiome predicts your risk of SSI following abdominal surgery. So, can probiotics prevent SSI? academic.oup.com/ofid/advance...
academic.oup.com
Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery
AbstractBackground. The relationship between preoperative intestinal microbiota composition and the development of surgical site infections (SSIs) followin
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Michael Calderwood @calderwoodmd.bsky.social · 02/05/2025
Next time you think to yourself, I miss paper charting, tell me if you read: 1. Frequent vs. Pregnant, 2. Positive vs. Routine, 3. Heparin 1000 units vs. 10000, 4. Hypertension vs. Hypotension, 5. Negative vs. Hepatitis
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Michael Calderwood @calderwoodmd.bsky.social · 02/05/2025
Bonding capital is what you do within a community to create more affinity between people. Bridging capital is when you reach across communities to groups that are not part of your own. We need both to create stronger organizations and stronger societies. www.ihi.org/insights/how...
ihi.org
How Better Use of Technology Can Free Up Time for Better Care
“We need to make technology work harder so that we can work smarter in health care.”
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Michael Calderwood @calderwoodmd.bsky.social · 02/05/2025
What about patient care will AI not replace: 1. Human connection at the bedside 2. Someone who truly cares and is worried about the outcome AI will challenge us to define what it means to be a human being.
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Michael Calderwood @calderwoodmd.bsky.social · 02/05/2025
Heard @theihi.bsky.social Leadership Alliance: 1. “Safety is a process of proactive risk mitigation” 2. “We need to understand work as it happens every day, not just when an event occurs” 3. “Let’s not buy new technology for a year and spend that money on optimizing technology that we have”
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Michael Calderwood @calderwoodmd.bsky.social · 02/05/2025
1/4 At the end of 2025, several tax provisions from the 2017 Tax Cuts and Jobs Act (TCJA) expire. Extending TCJA will add >$4 trillion to U.S. deficit over 10 years. TCJA disproportionately advantages those with more wealth. bipartisanpolicy.org/blog/the-new..., taxpolicycenter.org/taxvox/unpac...
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Michael Calderwood @calderwoodmd.bsky.social · 29/04/2025
We have an exciting opportunity to join @dartmouthhealth.bsky.social as the Chief of Infectious Diseases. Please message me if you have questions. This is a wonderful opportunity to lead an incredible team in a beautiful part of the country. dhcareers.org/job/section-...
dhcareers.org
Section Chief of Infectious Diseases and International Health - Healthcare Careers at Dartmouth Hitchcock Medical Center and Clinics
OverviewSection Chief of Infectious Diseases and International Health– Department of MedicineDartmouth-Hitchcock Medical CenterLebanon, NHDartmouth-Hitchcock Medical Center (DHMC), located in the Uppe...
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Michael Calderwood @calderwoodmd.bsky.social · 29/03/2025
“Leaders move along a continuum from inspiring to infuriating, and where they land at any given time depends on how well they play 3 key roles. … Visionaries give us meaning & purpose; exemplars provide us with passion & protection; and mentors bring us belonging & status.” hbr.org/2025/03/what...
hbr.org
What Sets Inspirational Leaders Apart
When people around the world are asked to reflect on both inspiring leaders and infuriating leaders, they point to three factors that distinguish the former from the latter. Inspiring leaders are visi...
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Michael Calderwood @calderwoodmd.bsky.social · 29/03/2025
When trying to diagnose Jamestown Canyon virus disease, it is worth noting the high seroprevalence (prior exposure) in endemic states such as Massachusetts, Minnesota, and Wisconsin. I suspect that this is also true in Northern New England. academic.oup.com/cid/advance-...
academic.oup.com
Jamestown Canyon Virus Seroprevalence in Endemic Regions and Implications for Diagnostic Testing
Estimated population seroprevalence for Jamestown Canyon virus infection is high in endemic areas. Interpreting diagnostic testing is challenging and requi
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Michael Calderwood @calderwoodmd.bsky.social · 29/03/2025
Routine use of rifampin in not recommended for staphylococcal native valve endocarditis. But what if patient undergoes valvular surgical intervention? The answer is still no. Not only does rifampin combination therapy not help, it may cause harm. academic.oup.com/ofid/advance...
academic.oup.com
Post-Operative Treatment Regimens in Patients with Native Valve Endocarditis due to Staphylococcus aureus who Undergo Valve Replacement or Repair
S. aureus NVE patients may have better outcomes (adverse events and drug-drug interactions, six-month infective endocarditis relapse and one-year mortality
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Michael Calderwood @calderwoodmd.bsky.social · 10/03/2025
Sharing two quotes from Edgar Schein’s “Humble Inquiry” that I finished this weekend; they seem even more relevant in our current era.
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Michael Calderwood @calderwoodmd.bsky.social · 07/03/2025
1/4 Vit A supplementation for treating measles: This is based on studies showing an association between prevalence of Vit A deficiency and measles mortality; however, evidence in support of Vit A supplementation has not reached statistical significance. pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Population-Level Risk Factors Related to Measles Case Fatality: A Conceptual Framework Based on Expert Consultation and Literature Review
A better understanding of population-level factors related to measles case fatality is needed to estimate measles mortality burden and impact of interventions such as vaccination. This study aimed to ...
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Michael Calderwood @calderwoodmd.bsky.social · 06/03/2025
I am getting a lot of questions about measles. Here are some thoughts on measles vaccination, as a number of people are asking about boosters.
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Michael Calderwood @calderwoodmd.bsky.social · 08/02/2025
Fascinating paper showing missed diagnoses identified on autopsy. Speaks to the need for better pleuropulmonary and CNS diagnostic testing. A fair bit of TB was missed, but this may not reflect US experience (paper from Iran). Regardless, message holds. academic.oup.com/ofid/advance...
academic.oup.com
Infectious Causes of Death: An Autopsy-Based Study of 546 cases
Among infectious disease-related deaths, autopsies revealed a 22.4% diagnostic discrepancy rate. Pleuropulmonary infections were the leading cause of death
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Michael Calderwood @calderwoodmd.bsky.social · 08/02/2025
Nice discussion about “a more efficient and effective quality measurement enterprise that contributes to clinician well-being while enhancing the quality impact of performance measurement.” qualitysafety.bmj.com/content/earl...
qualitysafety.bmj.com
The beast and the burden: will pruning performance measurement improve quality?
Programmes dedicated to driving improvement in healthcare quality have grown dramatically in the last two decades. Accreditation programmes along with performance measurement and reporting have been c...
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Michael Calderwood @calderwoodmd.bsky.social · 08/02/2025
Thoughtful discussion on a path forward focussed on the following 4 tenets to “transform diversity backlash”: Fairness, Access, Inclusion, Representation. hbr.org/2025/01/what...
hbr.org
What Comes After DEI
While backlash to DEI has challenged how many companies and practitioners approach creating more equitable workplaces, fewer have considered whether DEI work itself has room to improve. A new framewor...
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Michael Calderwood @calderwoodmd.bsky.social · 08/02/2025
Across ~750k inpatients in 928 U.S. hospitals, starting with empiric narrow-spectrum antibiotics escalated to broad-spectrum antibiotics based on cultures was NOT associated with worse outcomes compared with empirically starting broad (done close to 90% of the time). academic.oup.com/cid/advance-...
academic.oup.com
Association between Delayed Broad-Spectrum Gram-negative Antibiotics and Clinical Outcomes: How Much Does Getting It Right with Empiric Antibiotics Matter?
Empiric antibiotics are frequently unnecessarily broad-spectrum. This study compared clinical outcomes between matched patients who received early vs. dela
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Michael Calderwood @calderwoodmd.bsky.social · 08/02/2025
Thoughtful challenge to 30 yrs of clinical practice. FQ ppx to prevent SBP in pts w/ cirrhosis based on low quality evidence and a/w ⬆️ resistant bacteria, longer hospitalizations, C diff, ⬆️ gut translocation due to microbiome disruption, and ⬆️ rates of recurrent SBP. academic.oup.com/cid/advance-...
academic.oup.com
Rethinking Antibiotic Prophylaxis for Spontaneous Bacterial Peritonitis in Patients with Cirrhosis: First, Do No Harm
Abstract. Antibiotic prophylaxis for spontaneous bacterial peritonitis (SBPPr) in patients with cirrhosis has been considered standard of care since the 19
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Michael Calderwood @calderwoodmd.bsky.social · 05/02/2025
Thoughts for a Wednesday.
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
“QI is a humanistic response to solving problems. It is personal in both [how we] engage humans in change and the outcomes that matter to us enough to make these efforts.” “Leaders must be strong but humble, curious yet compassionate, inspiring and predictable.” qualitysafety.bmj.com/content/earl...
qualitysafety.bmj.com
Art of leading quality improvement
In their article in this issue of BMJ Quality and Safety , ‘ We listened and depended on and supported each other’ , Ginsburg et al examine how leaders shaped the site-level experience in a quality im...
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
Urgent care centers have been reported to have higher rates of inappropriate antibiotic prescribing. Study demonstrated that active participation in 3 PDSA cycles successfully reduced inappropriate antibiotic prescribing, although some racial disparities persisted. www.cambridge.org/core/journal...
cambridge.org
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
“When done right, team rituals provide certainty, connection, & space for employees to engage with each other & connect to the purpose of their work. In this way, rituals become a stabilizing force that helps unite & shepherd employees through whatever storms come their way.” hbr.org/2025/01/the-...
hbr.org
The Surprising Power of Team Rituals
Rituals — collective activities that team members regularly engage in and attribute meaning to — can make a big difference during times of change or transition. Research, which included a survey of 92...
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
“Leaders of the 20th century were question answerers, setting the vision and strategy from above. … Leaders in the 21st century are question askers. They seek feedback and new perspectives, and they ask curious questions about themselves, their teams, and their environment.” hbr.org/2024/10/6-es...
hbr.org
6 Essential Leadership Skills — and How to Develop Them
The way we work has changed — and so has leadership. Leaders are under new pressures to perform at higher levels and adapt quickly to changing demands. In this article, the author shares advice from t...
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
A negative urinalysis (- LE, - nitrite, <10 WBCs/hpf) has a negative predictive value of 98% in urine collected from neutropenic patients. These patients don’t need to be excluded from lab reflex protocols. academic.oup.com/cid/advance-...
academic.oup.com
Improving UTI Diagnostics in Oncology: Reliability of Reflex Urine Culture in Immunosuppressed Neutropenic and Non-neutropenic Cancer Patients
This retrospective study assessed performance dynamics of urine screen methods to detect clinically significant bacteriuria in cancer patients. A dipstick
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Michael Calderwood @calderwoodmd.bsky.social · 18/01/2025
Interesting study showing that antibodies in saliva are a better correlate of protection than antibodies in serum when it comes to protection against symptomatic #COVID19. Highlights the importance of robust induction of mucosal immune responses. academic.oup.com/ofid/advance...
academic.oup.com
Correlates of protection against symptomatic COVID-19: the CORSER 5 case-control study
AbstractBackground. Establishing correlates of protection often requires large cohorts. A rapid and adaptable case-control study design can be used to iden
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Michael Calderwood @calderwoodmd.bsky.social · 30/12/2024
Childhood deaths before age 5 in the U.S. have dropped from 40-50% (1800s) to <1% thanks to closed sewers, pasteurization, federal regulations preventing the addition of harmful chemicals to food, vaccines, and antibiotics. theconversation.com/infectious-d...
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Michael Calderwood @calderwoodmd.bsky.social · 29/12/2024
In a prospective trial of a passive diversion device in an ED setting, blood culture contamination rate decreased 60%. academic.oup.com/ofid/advance...
academic.oup.com
Prospective Trial of a Passive Diversion Device to Reduce Blood Culture Contamination
AbstractBackground. Blood culture contaminants can lead to inappropriate antibiotic use, prolonged length of stay, and additional hospital costs. Several d
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Michael Calderwood @calderwoodmd.bsky.social · 15/12/2024
“On their own, conflict, climate change, and the resurgence of disease would each present a serious risk to the world’s health. The US must prioritize all of them, or else we risk having them boil over into global health catastrophes.” www.healthaffairs.org/doi/10.1377/...
healthaffairs.org
Three Global Health Priorities For The Next Administration | Health Affairs Journal
Every presidential administration enters office facing threats to global health. But the incoming Trump administration enters office at a particularly dangerous moment. On their own, conflict, climat
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Michael Calderwood @calderwoodmd.bsky.social · 15/12/2024
Following the relaxing of #COVID19 restrictions, we have seen surges in flu, RSV, and Group A Strep infections. There was a waning of immunity to these infections as fewer people were exposed due to masking and social distancing. academic.oup.com/jid/advance-...
academic.oup.com
Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic
Antibodies to respiratory syncytial virus and Group A Streptococcus waned significantly in a longitudinal cohort throughout the pandemic. This waning may h
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Michael Calderwood @calderwoodmd.bsky.social · 12/12/2024
Editorial: Evidence that universal gloving, contact precautions, cohorting & environmental decontamination ⬇️ MDRO transmission is low. Evidence for patient decolonization is moderate. ‘The world is covered with a thin patina of feces.’ Call for paradigm shift. qualitysafety.bmj.com/content/earl...
qualitysafety.bmj.com
Low-quality evidence on practices to prevent transmission of resistant organisms calls for rigorous trials and a paradigm shift
This edition of BMJ Quality & Safety includes a systematic review on practices to reduce transmission of infections with resistant organisms led by the Agency for Healthcare Research and Quality (AHRQ...
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Michael Calderwood @calderwoodmd.bsky.social · 12/12/2024
“Leaders will never have time on their hands. … Leaders shouldn’t spend their scarce time on activities simply because they are very important. They should do only the things that nobody else in the organization can do nearly as well—if at all.“ hbr.org/2025/01/lead...
hbr.org
Leaders Shouldn’t Try to Do It All
The authors, a former CEO of Procter & Gamble and a former dean of the Rotman School, respectively, frequently find themselves sitting across the table from overwhelmed leaders. These executives are t...
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Michael Calderwood @calderwoodmd.bsky.social · 12/12/2024
Choosing Wisely: You are called about giving abx prophy to a close contact of someone who had invasive Group A Strep infection. Evidence suggests no ⬇️ in GAS infection in those who get prophylaxis, but there is a THREE FOLD ⬆️ incidence of adverse drug rxn. Say no. academic.oup.com/cid/advance-...
media.tenor.com
a man in a knight 's armor stands in front of a fire with the words " you have " written below him
ALT: a man in a knight 's armor stands in front of a fire with the words " you have " written below him
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Michael Calderwood @calderwoodmd.bsky.social · 12/12/2024
Of ~125k pts w/ suspected sepsis across 236 U.S. hospitals, only 1 in 5 had broad-spectrum abx (anti-MRSA, anti-PsA) de-escalated by day 4 when no resistant organisms identified. After propensity matching, de-escalation a/w ⬇️ AKI, ICU days, and inpatient mortality. academic.oup.com/cid/advance-...
academic.oup.com
Epidemiology and Outcomes of Antibiotic De-escalation in Patients with Suspected Sepsis in US Hospitals
Across 236 US hospitals, de-escalation of anti-MRSA and anti-pseudomonal antibiotics in suspected sepsis was infrequent and variable across hospitals. De-e
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Michael Calderwood @calderwoodmd.bsky.social · 11/12/2024
Cool tool for estimating risk of TB within first 5 years of immigration to a low incidence country. tb-migrate.shinyapps.io/website/ (Validation here: academic.oup.com/cid/advance-...)
tb-migrate.shinyapps.io
TB-MIGRATE V1.0
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Michael Calderwood @calderwoodmd.bsky.social · 11/12/2024
Got sepsis? Want to give a beta-lactam and vancomycin empirically while figuring things out? Give the beta-lactam first. Goes in quick, unlike the vanco. Makes a difference. Meaning: fewer patients die. academic.oup.com/cid/advance-...
academic.oup.com
Association Between the Sequence of β-lactam and Vancomycin Administration and Mortality in Patients with Suspected Sepsis
Amongst 25,391 patients with suspected sepsis prescribed vancomycin and β-lactam therapy, administering β-lactams before vancomycin was associated with an
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Michael Calderwood @calderwoodmd.bsky.social · 11/12/2024
I feel I must say…please don’t use bat guano to fertilize your cannabis. Two fatal cases of Histoplasmosis in Rochester, NY. #TheMoreYouKnow academic.oup.com/ofid/advance...
academic.oup.com
Histoplasmosis Associated with Bat Guano Exposure in Cannabis Growers: Two Cases
Abstract. Histoplasma capsulatum is a pathogenic dimorphic fungus with evolving epidemiology. Initially described as endemic to the Ohio and Mississippi ri
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Michael Calderwood @calderwoodmd.bsky.social · 05/12/2024
“Hopeful people…believe that things might turn out well — but they also believe that in that context of uncertainty, actions matter. Being hopeful…involves willpower (a desire to bring about hoped for outcomes), and waypower (the charting of a clear path to achieve them).” hbr.org/2024/12/the-...
hbr.org
The Strategic Power of Hope
Negativity attracts attention and is often equated with intelligence, so it’s no surprise that leaders often feel they need to focus on what might go wrong. That kind of defensive posture can be helpf...
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Michael Calderwood @calderwoodmd.bsky.social · 30/11/2024
When reliability is high, observed scores better reflect true performance (higher signal:noise). “Reliability needs to reach at least 0.7 for 50% of flagged organisations to be correctly flagged and 0.9 to nearly eliminate incorrectly flagging organizations.” qualitysafety.bmj.com/content/earl...
qualitysafety.bmj.com
The good, the bad and the ugly: What do we really do when we identify the best and the worst organisations?
Identifying high and poorly performing organisations is common practice in healthcare. Often this is done within a frequentist inferential framework where statistical techniques are used that acknowle...
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Michael Calderwood @calderwoodmd.bsky.social · 30/11/2024
“Leaders who successfully carried out their sponsorship role went beyond transactional behaviours and the removal of implementation barriers. … [A leader must] build a common vision and engage in two-way relationship building and interactive problem solving.” qualitysafety.bmj.com/content/earl...
qualitysafety.bmj.com
‘We listened and supported and depended on each other’: a qualitative study of how leadership influences implementation of QI interventions
Background There is growing recognition in the literature of the ‘Herculean’ efforts required to bring about change in healthcare processes and systems. Leadership is recognised as a critical lever fo...
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Michael Calderwood @calderwoodmd.bsky.social · 26/11/2024
As we think about how we continue to serve as agents of change, is important that we delineate our values, weave these values into everything that we do, be aggressively authentic, and then find common ground to drive improvement.
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Michael Calderwood @calderwoodmd.bsky.social · 26/11/2024
Celebrating and supporting Men’s Health @dartmouthhealth.bsky.social. Focus on prostate cancer, testicular cancer, mental health, and suicide prevention. Please consider supporting: cancer.dartmouth.edu/donate/frien....
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Michael Calderwood @calderwoodmd.bsky.social · 25/11/2024
1 out of every 7-8 Americans says they don’t have a regular source of healthcare, and 1 out of 12-13 Americans don’t have any health insurance. Americans spend an average of 7.3% of their annual income on healthcare. As a country, we are not upholding the Hippocratic oath. hbr.org/2024/11/why-...
hbr.org
Why the U.S. Healthcare System Is So Much Worse Than Its Peers
Given its collective wealth, technologic sophistication, and spending, the United States should lead, not lag, the world in its healthcare performance. But based on 70 performance measures across five...
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Michael Calderwood @calderwoodmd.bsky.social · 22/11/2024
About 1/3 of surveyed providers do not regularly examine patients before ordering fever work-up. 66% always or often order “full fever work-up,” 77% when instructed to do so in handoff instructions. www.cambridge.org/core/journal...
cambridge.org
Provider &amp; nursing perspectives on the “panculture”: opportunities for innovative diagnostic stewardship interventions | Antimicrobial Stewardship &amp; Healthcare Epidemiology | Cambridge Core
Provider &amp; nursing perspectives on the “panculture”: opportunities for innovative diagnostic stewardship interventions - Volume 4 Issue 1
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Michael Calderwood @calderwoodmd.bsky.social · 22/11/2024
In a study of patients meeting NHSN criteria for CAUTI, 18% met clinical definition, 42% were indeterminate, and 40% were catheter-associated asymptomatic bacteriuria. www.cambridge.org/core/journal...
cambridge.org
Recognizing asymptomatic bacteriuria in the surveillance of catheter-associated urinary tract infections—beyond fever and positive urine culture | Antimicrobial Stewardship &amp; Healthcare Epidemiolo...
Recognizing asymptomatic bacteriuria in the surveillance of catheter-associated urinary tract infections—beyond fever and positive urine culture - Volume 4 Issue 1
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Michael Calderwood @calderwoodmd.bsky.social · 22/11/2024
Across 14 studies with ~21k patients, PICC lines had a two-fold higher risk of bloodstream infection than midlines, but midlines had higher rates of superficial vein thrombosis, infiltrations, and leaks. PICCs are higher cost and have higher patient dissatisfaction. www.cambridge.org/core/journal...
cambridge.org
Which is the safer option for adult patients between peripherally inserted central catheters and midline catheters: a meta-analysis | Infection Control &amp; Hospital Epidemiology | Cambridge Core
Which is the safer option for adult patients between peripherally inserted central catheters and midline catheters: a meta-analysis
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Michael Calderwood @calderwoodmd.bsky.social · 21/11/2024
Study showed that increasing the percentage of patients with a bone and joint infection (including PJI) discharged on an oral antibiotic had no negative impact on 90 day failure rates, while decreasing LOS (and PICC adverse events). academic.oup.com/ofid/advance...
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Michael Calderwood @calderwoodmd.bsky.social · 20/11/2024
“Right now, many of us feel suspended between what once was and what is yet to come.” Ask: 1. What do you value?, 2. Where do we stand?, 3. How can we move ahead? Make sure you: 1. Step back and take stock, 2. Strengthen the ties that bind, 3. “Hold fast and stay true.” hbr.org/2024/11/how-...
hbr.org
How to Lead When the Future Feels Unpredictable
Uncertain times abound, and as a result many of us are enduring a prolonged separation from our normal ways of being and doing. We are having liminal experiences, in other words — experiences that rep...
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Michael Calderwood @calderwoodmd.bsky.social · 17/11/2024
1/8 As an introduction, I am reposting a series of podcast that we created delving into topics that impact healthcare quality and safety. Our first podcast addressed burnout (creators.spotify.com/pod/show/the...).
creators.spotify.com
Calderwood Considers: Burnout by The Cure
For the inaugural episode of our new series; Calderwood Considers! Host Jessica Swain, Director of Infection Prevention and Control for Dartmouth Health, talks to Dr. Michael Calderwood, Chief Quality...
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Michael Calderwood @calderwoodmd.bsky.social · 17/11/2024
I am new to Bluesky, drawn by a hope that this is where the intelligent scientific discourse migrated following the demise of Twitter. Please reach out to let me know you are here. I like to post on infectious diseases, infection prevention, antibiotic stewardship, quality, safety, and leadership.
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