Reposted by Colm Healy
Is the link btwn Adolescent SSRI use & Bipolar Disorder causal?
Our study suggests: 𝐍𝐨.
When accounting for unmeasured confounding (e.g., depression severity) via Instrumental Variable analysis, the evidence for a causal link disappears.
mentalhealth.bmj.com/content/28/1...
#Psychiatry #MedSky
mentalhealth.bmj.com
Antidepressant treatment and risk of subsequent bipolar disorder in adolescents with unipolar depression
Background Selective serotonin reuptake inhibitors (SSRIs) are a common treatment for depression and anxiety in adolescents but are associated with an increased incidence of bipolar disorder (BD). Whe...