BuechlerLab @buechlerlab.bsky.social · 17/07/2026Such a crucial question. We are trying to find ways that enable scaling at ~1000x with learning the fundamentals - this is an challenge but essential 010
BuechlerLab @buechlerlab.bsky.social · 03/07/2026Proud to contribute to a seminal study in #ScienceMagazine revealing the importance of #ILC2-#Pi16+ #Fibroblast interactions in the pancreas. Forever grateful to @timotheus_halim & congrats to the co-authors! tinyurl.com/fmypdbme buechlerlab.comtinyurl.comILC2s regulate a fibroblast progenitor niche in the pancreasLocal fibroblast development and densities influence organ health and disease, although it remains unclear how tissue fibroblast topography is controlled in situ. Here, we defined Group 2 innate lymph... 041
BuechlerLab @buechlerlab.bsky.social · 20/06/2026The #buechlerlab is looking for #postdoc(s) to study how #fibroblasts control #inflammation and #immunity. Please see below and reach out if you are interested~ www.buechlerlab.com 033
BuechlerLab @buechlerlab.bsky.social · 10/06/2026Tour du force on how #fibroblast subsets can drive rheumatoid arthritis in #natureimmunology. Huge congrats to @arthritisbham, Mark Coles and team at #Oxford. Check it out: www.nature.com/articles/s41...nature.comThe embryonic origins of site-specific arthritis - Nature ImmunologyDavidson et al. map the cellular and structural composition of developing joints and identify fibroblast populations that may predispose joints to inflammatory arthritis. 042
BuechlerLab @buechlerlab.bsky.social · 27/05/2026Congrats to Drs. Shyer, Vander Heiden, Turley and team for leading an important study of #fibroblast development, diversification and function in fibrosis published in #PNAS. Happy to have contributed expertise from #UofT, #Sickkids and #UnityHealth in Toronto. Check it: www.pnas.org/doi/10.1073/...pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 000
BuechlerLab @buechlerlab.bsky.social · 31/03/2026We are looking for motivated scientists to join our team, please reach out if you feel you are a good fit~ 011
BuechlerLab @buechlerlab.bsky.social · 22/03/2026We are interested in adding #postdocs. If you like a fabulous team, city and research environment and are interested in #cellularengineering / #sytheticbiology, #ILCfibroblast interactions or #skin #fibrosis, contact me with your CV & interest statement. www.buechlerlab.com 011
BuechlerLab @buechlerlab.bsky.social · 10/03/2026Thank you to Rundong Jiang & Johann E. Gudjonsson for their News and Views piece on our recent Nature Immunology article! Check it out~ www.nature.com/articles/s41... 010
BuechlerLab @buechlerlab.bsky.social · 02/03/2026So glad to share our new work in #NatureImmunology highlighting that #fibroblast-#macrophage dialogue is a cornerstone of skin integrity in health and disease. Big congrats to all the authors at #UofT and #Genentech for their tireless efforts. Looking for #PDs to continue this work~ rdcu.be/e50PJrdcu.beReciprocal regulation of fibroblast–macrophage equilibrium governs skin integrityNature Immunology - Turley, Buechler and colleagues show that dermatopontin-expressing fibroblasts provide CSF1 to form a supportive niche for skin-resident macrophages. This interaction is... 041
BuechlerLab @buechlerlab.bsky.social · 08/01/2026Interested in utilizing novel genetic tools to unpack the #immunology of #fibroblasts in #regenmed, #cancer, #metabolism, #osteoarthritis or #fibrosis and hope to make a dent in the universe? We are looking for #postdocs and #Canada is offering amazing opportunities for funding. www.buechlerlab.com 011
BuechlerLab @buechlerlab.bsky.social · 23/08/2025Thanks for a wonderful session #iuis2025 and #csi for the fabulous session on #fibroblasts and #stroma in #immunity! See you all in 2028 in Toronto! 041
BuechlerLab @buechlerlab.bsky.social · 01/08/2025The Buechler and Kapoor labs are teaming up to find a talented postdoc to work jointly between our labs at UofT/UHN. If you want to make a dent in the universe, please DM. #Immunology #fibroblast www.buechlerlab.com and www.kapoorlab.ca 012
BuechlerLab @buechlerlab.bsky.social · 07/01/2025Happy to share a preprint on how #fibroblasts maintain a niche for #macrophages in the skin. A fab collaborative effort between PDs and trainees at #uoft and #genentech. www.biorxiv.org/content/10.1... www.buechlerlab.combiorxiv.orgDermatopontin-expressing fibroblasts mediate an essential skin macrophage nicheFibroblasts are present in all tissues and are crucial for maintaining tissue homeostasis. We previously identified fibroblasts marked by Dermatopontin ( Dpt ) but their role in supporting macrophage ... 151