iiinova — where your digital self keeps evolving

Brandon Carpenter @bscarp84.bsky.social · 12/06/2026

Thanks for the shoutout Dave:) What a great meeting so far!

Brandon Carpenter @bscarp84.bsky.social · 20/05/2026

That’s a wrap for 2026 SESDB meeting! Thank you to all the faculty that helped me organize this meeting and all the students who helped make the conference come to life.

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Brandon Carpenter @bscarp84.bsky.social · 24/03/2026

Ahh, pollen is in the air. Must be that time of year again…..to submit your abstracts and register for the 2026 SESDB meeting!

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Brandon Carpenter @bscarp84.bsky.social · 07/03/2026

This image is amazing:) Excited to read!

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Reposted by Brandon Carpenter

Society for Developmental Biology @socdevbio.bsky.social · 03/03/2026

The next the Ethel Browne Harvey Postdoc Seminar will be held Friday, February 13 at 3 pm Eastern Time with Martha Echevarría-Andino @uwmadison.bsky.social and M. Fernanda Palominos @ucberkeleyofficial.bsky.social. Register today and join us. bit.ly/47QVIEK #SDBPostdocSeminar

Society for Developmental Biology Ethel Browne Harvey Postdoctoral Seminar Series
Friday, March 13, 2026, 3:00pm - 4:00 pm Eastern Time
Martha Echevarría-Andino (University of Wisconsin-Madison)
Hoxa11/Hoxd11 transcription factors regulate extracellular matrix genes during osteochondral differentiation
M. Fernanda Palominos (University of California, Berkeley)
Novel craniofacial genes linked to extreme jaw evolution in pupfishes revealed by tissue-specific transcriptomics and speciation genomics

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Reposted by Brandon Carpenter

David Katz @katzlab.bsky.social · 23/02/2026

Don’t forget to register for the C. elegans topic meeting June 10-14 in Madison, WI. Early bird registration deadline this Friday 2/27! uwmadison.eventsair.com/mapsdev26/

uwmadison.eventsair.com

Home - 2026 MAPSS + DevCell

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Brandon Carpenter @bscarp84.bsky.social · 13/02/2026

Thanks T, and back at you! Look at us, just a bunch of science NuRDs

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

This project represents the best of collaborative, curiosity-driven science—from undergraduates at a PUI taking their first steps at the bench to a full research teams from R2 and R01 Universities uncovering how epigenetic systems maintain developmental fidelity.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

Our findings highlight how transcriptional repression, chromatin remodeling, and histone methylation reprogramming synergize to prevent somatic tissues from adopting germline-like transcriptional states.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

Thats not all...🔹 Using genetic knockdowns and large genomic sequencing analyses, we show that these complexes physically associate at SPR 5/MET 2 targets—revealing a coordinated, multilayered gene regulatory mechanism that maintains the germline–soma distinction.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

In this study....drum roll🥁! 🔹 We found that compromising either the DREAM transcriptional repressor complex or the MEC NuRD chromatin remodeling/HDAC complex exacerbates the developmental delay and ectopic germline gene expression observed in spr 5; met 2 mutants.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

*Major Highlights From Our Paper* Our previous work demonstrates that SPR-5 (an H3K4 demethylase) and MET-2 (an H3K9 methyltransferase) normally work together during fertilization to erase inherited epigenetic marks and prevent germline genes from staying active in somatic tissues.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

What makes this publication especially meaningful is that it started with CURE students from Oglethorpe University. Their initial experiments laid the foundation for a question that grew into a multi-institutional project including Emory University and Kennesaw State University.

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Brandon Carpenter @bscarp84.bsky.social · 12/02/2026

Excited to Share Our New Publication in #GENETICS! academic.oup.com/genetics/adv... Check out our new publication of our research exploring how the DREAM and MEC NuRD complexes reinforce SPR 5/MET 2 maternal reprogramming to safeguard proper developmental cell fates in C. elegans.

academic.oup.com

The Dream and MEC NuRD complexes reinforce SPR-5/MET-2 maternal reprogramming to maintain the germline-soma distinction

Abstract. The proper coordination of transcription factors, ATP dependent chromatin remodelers and histone modifications is essential for tissue specific g

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