1/ Our new paper is out today in @NatureComms 🎉
We mapped single-cell eQTLs in subcutaneous adipose tissue from 127 people with obesity, and linked them to genetic risk for 33 cardiometabolic and aging traits.
www.nature.com/articles/s41...
nature.com
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging - Nature Communications
Obesity predisposes to cardiometabolic comorbidities and accelerated biological aging. Here, the authors identify cell-type level regulatory variants and their epigenomic landscape underlying this pre...