iiinova — where your digital self keeps evolving

Brian Space @brianspace.bsky.social · 01/10/2026

National BlacK Dog 🐶 Day - 3 generations of Space family doggos ! Grizzly, Cosmos, Bear and Tatum

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Brian Space @brianspace.bsky.social · 30/09/2026

These are awful times. Random destruction of lifetimes of work.

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Brian Space @brianspace.bsky.social · 30/09/2026

Our new puppy Tatum 🍀 🏀 🍀

A picture of a 6 month old black shepherd puppy

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Brian Space @brianspace.bsky.social · 28/09/2026

As a lifelong 🍀 Celtic’s 🏀 fan can also say JB is a great player, decent human and great teammate. You folks will be delighted to have him.

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Brian Space @brianspace.bsky.social · 15/09/2026

Listening it struck me how well you answer questions by stating your position and level of certainty while being neither judgmental nor wishy washy. It’s an amazing talent. I appreciate your work, ty.I listen taking 15 yr olds 🚙 to school and it takes us weeks per ama with a lot of conversation.

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Brian Space @brianspace.bsky.social · 11/09/2026

They are Amamzing ! Never knew I could be excited and posting about an 🍎!

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Brian Space @brianspace.bsky.social · 10/09/2026

Absolutely.💯 and for fairly straightforward reasons that should be obvious to them. It makes me wonder 💭 how much they have seriously contemplated the potential strengths and weaknesses of AI itself.

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Brian Space @brianspace.bsky.social · 08/09/2026

Of course they do they smell like dogs 🐶

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Brian Space @brianspace.bsky.social · 08/09/2026

Prediction markets albeit imperfect in their current form are far more useful than sports betting sites imo. Current sports betting is theft and exploitation with almost no redeeming qualities. In many states they tax losses exploiting people and offer nothing in return but unbeatable rake.

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Brian Space @brianspace.bsky.social · 01/08/2026

That’s wonderful news. Good for you, your folks, the US and world 🌎 😃

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Brian Space @brianspace.bsky.social · 16/07/2026

What if I am watching on a plane and have money line and spread bets 🤷‍♂️

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Brian Space @brianspace.bsky.social · 01/07/2026

They can pack sand . Cheap loser bastards. Total betrayal. Total incompetence. Executive failure of the century.

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Brian Space @brianspace.bsky.social · 18/06/2026

www.nature.com/articles/s41... New paper with our fantastic collaborators!

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Brian Space @brianspace.bsky.social · 11/06/2026

Funny having grown up in Philly - who has a bunch of wonderful fans - but also violent and quite insufferable versions I see them as quite similar. I watched a lot of people wearing opposing jerseys get beat up at Sixers games. Was very common as an a example so just saying those in glass houses 🏠

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Brian Space @brianspace.bsky.social · 01/06/2026

Thank you for another great AMA. Grateful.

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Brian Space @brianspace.bsky.social · 31/05/2026

Suddenly okc is in salary cap trouble with two big non performing salaries and people to pay with 3 salaries alone putting them at the tax or beyond. How quickly it all changes. The Celtics are in much better shape.

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Brian Space @brianspace.bsky.social · 29/05/2026

While there can even be dynamic or non-dynamic MD simulations, it’s always Molecular Dynamics.

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Brian Space @brianspace.bsky.social · 07/03/2026

The big 3 back together let’s goooo 🍀🏀🍀🏀🍀

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Brian Space @brianspace.bsky.social · 28/02/2026

Tough but incompetent? 🤷‍♂️

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Brian Space @brianspace.bsky.social · 23/02/2026

Your posts and contributions are incredibly valuable — thank you. 🧪 🧫 🧬

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Brian Space @brianspace.bsky.social · 18/02/2026

Not to mention that fiscal conservatism becomes a huge priority when there is a D administration. That’s what they see in the numbers I strongly suspect. Hard to see how they don’t mention it if they are seriously studying the issue as opposed to other purposes.

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Brian Space @brianspace.bsky.social · 02/02/2026

Terrific AMA as always. Well done and thank you for your time and commitment.

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Brian Space @brianspace.bsky.social · 01/02/2026

I rejected the same paper 3 time and it appeared still very wrong and unchanged in JACS. I gave lots of constructive advice that was ignored. They fell up ⬆️ was disappointing. People who publish like that mostly skate and are successful in my experience.

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Brian Space @brianspace.bsky.social · 24/01/2026

Imagine a team where JT is striving to be the best player and the question answers itself. 🍀 🏀 🍀

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Brian Space @brianspace.bsky.social · 23/11/2025

Feel free to reach out I do this on a very busy professor life. It’s pretty straight forward but it’s also easy to waste a lot of effort.I use a band system (X3) it’s inexpensive and can travel with it. It’s very low injury as you age this is critical. Follow Peter Attia is a strong recommend.

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Brian Space @brianspace.bsky.social · 23/11/2025

David - spent a lot of time over the past decade figuring this stuff out. I do 15 minutes or stretching and resistance every morning and some pull ups. Do supplements but really it’s protein that’s critical. See my pinned post for a recent experiment that’s shows i maintain muscle even on a diet.

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Brian Space @brianspace.bsky.social · 21/11/2025

Maintenance of muscle mass is a huge problem for almost all men and women as they age and leads to injury and even poor maintenance of things like blood sugar. 8/n

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Brian Space @brianspace.bsky.social · 21/11/2025

And it is nice to know I could use a low dose in the future if I struggle. And a word of caution if you don’t do resistance training religiously and eat protein you will lose a lot of muscle and that can put you in a worse spot health wise than the fat depending on your particulars. 7/n

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Brian Space @brianspace.bsky.social · 21/11/2025

Uploading the below thread photos into pro Gemini also figured out my protocol from the data. Brave new world indeed. Its analysis was excellent btw just giving it the photos posted here. When prompted Gemini also offered a thoughtful protocol as I withdraw from trizepatide. 6/n

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Brian Space @brianspace.bsky.social · 21/11/2025

I got a dexa scan for body composition before I started and used the Hume scale daily ( it is a conductivity body composition scale ) and while it is noisy daily the weekly averages are good. It overestimated my body fat percent by 2-3% compared to dexa at the start. So next is the 7 week data. 5/n

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Brian Space @brianspace.bsky.social · 21/11/2025

I had nausea on the intermediate dose not horrible but unpleasant but also made not eating much at all completely easy. I had an experience with being able to not fight being a glutton for the first time in my life. Very illuminating. 4/n

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Brian Space @brianspace.bsky.social · 21/11/2025

However, even on 7 day water fasting I did not with daily resistance so i was hopeful. The results are stunning. Gemini calls me a hyper responder and indeed I can barely tolerate 5 mg doses and I don’t think I ate a full meal in 8 weeks certainly not on the intermediate dose. 3/n

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Brian Space @brianspace.bsky.social · 21/11/2025

I decided to try trizepatide for 2 months at low and intermediate doses. Recognizing that it can deplete muscle 💪🏽 I was careful to eat high quality protein bars and I do daily resistance training mornings. Many people lose a lot of muscle on trizepatide. 2/n

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Brian Space @brianspace.bsky.social · 21/11/2025

My experience with trizepatide: I was stuck for -over 5 years at higher body fat than I’d like and it would not budge. I continued to add muscle but even after 7 day water fasts or a month of indulgence I would go back to about 25% body fat. 1/n

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