Our NAR paper is officially out (doi.org/10.1093/nar/...). Digging in to how TFs work as a function of where they bind, what they bind to and which promoter they regulate on synthetic promoters designed to be regulated ONLY by that TF. Huge effort by both Sunil and Vinu.
doi.org
A systematic survey of TF function in E. coli suggests RNAP stabilization is a prevalent strategy for both repressors and activators
Abstract. Transcription factors (TFs) are often classified as activators or repressors, yet these context-dependent labels are inadequate to predict quanti