iiinova — where your digital self keeps evolving

Komal Jhaveri, MD, FACP, FASCO @breastcancerdoc.bsky.social · 25/10/2025

Honored to receive a research grant from MWCABC at their inspiring Ladies’ Night Out event.This will help advance our work at MSK exploring the role of IO in ER+ MBC. Grateful for MWCABC’s dedication to advancing research and supporting patients and families. #Gratitude #BreastCancerAwareness

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 28/08/2025

Breast medical oncologist and early drug development specialist @breastcancerdoc.bsky.social discusses how molecular subtyping, antibody-drug conjugates, and precision trials are reshaping the field of #breastcancer on @emjreviews.bsky.social lastest podcast. 🎙️ Listen here: bit.ly/422CWXd

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Reposted by Komal Jhaveri, MD, FACP, FASCO

MSK Department of Medicine @mskdeptofmed.bsky.social · 31/05/2025

Congrats to @breastcancerdoc.bsky.social, Nicholas Turner of @bcrfcure.bsky.social, & the team on their @NEJM study of overall survival results of inavolisib for PIK3CA-mutated #breastcancer. Dr. Turner will share more at 2:07 p.m. CT at #ASCO25. @mskcancercenter.bsky.social bit.ly/43xNnn3

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 31/05/2025

Session alert below with MSK expert @breastcancerdoc.bsky.social. #ASCO25

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Komal Jhaveri, MD, FACP, FASCO @breastcancerdoc.bsky.social · 30/05/2025

Whether you are attending @ASCO in person or virtually, join us for the educational session - “After a CDK4/6 inhibitor: State of theArt in HR+ MBC “today at 4.30 PM on Hall D2 - Seth Wander, Ricki Fairley, Rena Callahan @MSKCancerCenter @OncoAlert #bcsm #ASCO2025

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Reposted by Komal Jhaveri, MD, FACP, FASCO

The ASCO Post @ascopost.bsky.social · 07/01/2025

In this video @breastcancerdoc.bsky.social discusses the results of the phase III EMBER-3 trial of imlunestrant. She presented on this oral selective estrogen receptor degrader for #breastcancer treatment at #SABCS24. ascopost.com/videos/2024-...

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Sherry Shen, MD @sherryshenmd.bsky.social · 13/12/2024

When @breastcancerdoc.bsky.social & I are unintentionally matching at our poster on T-DXd in pts with HER2-low lobular MBC. PFS 7.2m in total cohort, shorter in those with PIK3CA/AKT/PTEN muts & trend toward longer in HER2mut. More research needed in lobular BC!

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 11/12/2024

New results from a clinical trial by MSK expert Dr. Komal Jhaveri (@breastcancerdoc.bsky.social) show an experimental drug (#imlunestrant) stops advanced #breastcancer from progressing in some people with tumors that have grown resistant to standard therapy. Learn more: bit.ly/3D3Qc4b

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Reposted by Komal Jhaveri, MD, FACP, FASCO

MSK Department of Medicine @mskdeptofmed.bsky.social · 11/12/2024

Congrats to Komal Jhaveri on the amazing results of her @nejm.org study that found imlunestrant–abemaciclib combo significantly improved progression-free survival for people with ER+, HER2- advanced #breastcancer. She presented this work at #SABCS24! @breastcancerdoc.bsky.social buff.ly/3OR1Ulj ➡️

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Sarat Chandarlapaty @saratchandarlapaty.bsky.social · 11/12/2024

Super plenary from Komal Jhaveri on imlunestrant #sabcs Congrats to her and the Ember-3 trial authors for developing this SERD (and combo with Abema)

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Stephanie L. Graff, MD FACP FASCO @drsgraff.bsky.social · 11/12/2024

EMBER3 Interesting subgroup breakdown shows the combo benefit persists independent of ESR1 status, prior CDK4/6 inhibition, and shows signal for CNS effect (very small numbers) #SABCS24 @breastcancerdoc.bsky.social @oncoalert.bsky.social @sabcs.bsky.social

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Stephanie L. Graff, MD FACP FASCO @drsgraff.bsky.social · 11/12/2024

Ember3: Safety profile of imlunestrant looks good—minimal GI toxicity, no class toxicity concerns. The combo AEs are what we expect with abema. #SABCS24 @breastcancerdoc.bsky.social @oncoalert.bsky.social

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Margaret Gatti-Mays, MD MPH @drgattimays.bsky.social · 11/12/2024

#EMBER3 results presented @sabcs.bsky.social #SABCS24 by @breastcancerdoc.bsky.social Main take aways: 1) Imlunestrant ⬆️ PFS > SOC in 1L, ESR1 mut, mER+ BC 2) Imlunestrant + abemaciclib ⬆️ PFS in 1L mER+ BC irrespective of ESR1 or PIK3CA mut 3) Imlunestrant ⬇️ CNS progression 4) OS immature #bcsm

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Kelly Shanahan @stage4kelly.bsky.social · 11/12/2024

Another up and coming (ie, may well be fda approved in the near future) agent is imlunestrant, as monotherapy or in combo with abemaciclib #SABCS24 @breastcancerdoc.bsky.social

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Reposted by Komal Jhaveri, MD, FACP, FASCO

Sherry Shen, MD @sherryshenmd.bsky.social · 11/12/2024

First Bluesky post! EMBER-3 presented by my mentor @breastcancerdoc.bsky.social demonstrating greater mPFS as single agent vs. SOC ET in ESR1mut, and impressive benefit of imlunestrant+abema with mPFS 9.4 months, 59% had prior CDK4/6i. Novel ET + CDK4/6i switch is intriguing - ELAINE3 is enrolling!

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