Brandon Stell @brandonstell.bsky.social · 07/12/2025While the complex spike error signal from a single pull can only provide miniscule LTD/LTP of parallel fibers onto a Purkinje cell, the combined effect across the population of Purks is robust enough to influence the very next joystick pull. 100
Brandon Stell @brandonstell.bsky.social · 07/12/2025Imaging complex spikes in populations of Purkinje cells during learning reveals the answer: bands of cells respond similarly. Together, these cells encode both the magnitude and the direction of the behavioral error. 100
Brandon Stell @brandonstell.bsky.social · 07/12/2025Like humans wearing prism goggles, mice learn to adapt their behavior in only a few trials (dark blue). They retain a memory of this adaptation, which they need to "unlearn" when returned to control conditions (light blue). 120
Brandon Stell @brandonstell.bsky.social · 07/12/2025We trained mice to use a joystick to retrieve water. To test their cerebellar learning, we imposed a perturbation (gain = 2x; lower panel) that they needed to overcome to retrieve the reward. 120
Brandon Stell @brandonstell.bsky.social · 24/01/2025Only one week left to apply to the Paris School for Neuroscience Techniques! parisneuro.ovh 166
