Anyone who has been through opioid withdrawal, or has cared for someone who has, knows that the pain does not end when the drug leaves the body. In a new…

Psychopharmacology - Drug exposure initiated in adolescence has been associated with more severe mental health outcomes related to substance abuse and anxiety disorders. The aim of the present...

Nature Communications - Neural mechanisms underlying cannabinoids’ anxiogenic effects are not fully understood. Here authors show that cannabinoids dose-dependently increased spontaneous...

Nature - The psychedelic psilocybin reorganizes brain activity into structured, context-aligned patterns that integrate internal and external processing, providing a neural basis for the felt...

​Senate appropriators from both parties are workshopping language that could be added to a spending bill to prevent the White House from exerting political influence on medical research grants. The provision would go into the Labor-HHS-Education appropriations bill that lawmakers hope to pass before stopgap funding expires Dec. 11. The senators, led by Appropriations Chair Susan Collins, R-Maine, and ranking […]

In this case-control study, Chuang Liang and colleagues systematically compare brain aging patterns and biological processes across multiple common brain disorders.

PARC pilot awards: $5,000 to $25,000 per year for biologically based addiction research using the Addiction Biobank and center cores. 2026 applications due…

UC San Diego researchers have received a $12.6 million award from the National Institute on Drug Abuse to establish the Polysubstance Addiction Research Center, a multidisciplinary center designed to uncover the biological factors that contribute to addiction across multiple substances.

Polysubstance Addiction Research Center (PARC), A NIDA P50 Center of Excellence at UC San Diego. Identifying convergent and divergent multiscale mechanisms…

Stories of science funding being cut, labs shutting down and scientists losing jobs have flooded the media under Trump's administration. These six graphics show how those changes have affected U.S.…

Linked Discoveries is an experimental tool to help scientists see how individual research findings relate to the larger body of biomedical evidence.

Molecular Psychiatry - Lifetime substance use disorder and suicidal behaviour: a population-based familial co-aggregation register study

Nature Communications - Opioid overdose can be deadly, and timely naloxone delivery remains challenging. Here, the authors develop a wearable acoustofluidic patch that detects overdose using...