iiinova — where your digital self keeps evolving

Bonev Lab @bonevlab.bsky.social · 26/06/2025

Congratulations, Jei! 🎉 We’re so proud of your journey and all that you’ve achieved. Thank you for all your incredible contributions! 🎓

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Reposted by Bonev Lab

Epigenetics Podcast @epigeneticspod.bsky.social · 11/04/2025

In this episode we talked with @boyanbonev.bsky.social from @bonevlab.bsky.social at @epihmgu.bsky.social about his work on neuroepigenetics, focusing on gene regulation, chromatin architecture, and primate epigenome evolution. #podcast #epigenetics Listen here: activemotif.com/podcasts-boy...

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Reposted by Bonev Lab

Boyan Bonev @boyanbonev.bsky.social · 04/04/2025

Can a stem cell change its epigenome while proliferating? In collaboration with the lab of Amos Tanay, we demonstrate that yes, the epigenome of neural stem cells (NSCs) is continuously remodeled, across multiple layers, during mouse corticogenesis. 1/14 www.biorxiv.org/content/10.1...

biorxiv.org

Neural stem cell epigenomes and fate bias are temporally coordinated during corticogenesis

The cerebral cortex orchestrates complex cognitive functions, yet how its distinct temporal lineages are molecularly patterned during development remains unresolved. Here, we integrate single-cell tra...

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Reposted by Bonev Lab

Silvia Vangelisti @silviavangelisti.bsky.social · 13/03/2025

Very happy to share the preprint of my main PhD project in the @bonevlab.bsky.social! Huge thanks to @boyanbonev.bsky.social, all co-authors and members of the @bonevlab.bsky.social! This work wouldn’t have been possible without your contributions!

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Reposted by Bonev Lab

Boyan Bonev @boyanbonev.bsky.social · 13/03/2025

🚨New preprint from @bonevlab.bsky.social 🚨: What are the key epigenetic mechanisms that drive species-specific gene regulation during primate neurogenesis - and how do they contribute to the evolution of the human neocortex? Here’s what we discovered 👇 www.biorxiv.org/content/10.1...

biorxiv.org

3D Epigenome Evolution Underlies Divergent Gene Regulatory Programs in Primate Neural Development

The expansion of the neocortex is a hallmark of human evolution and is closely linked to neural stem cell biology. Yet, the epigenetic mechanisms driving divergent gene regulation during primate neuro...

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