Nature Catalysis - The catalytic enantioconvergent nucleophilic fluorination of alkyl halides using inexpensive alkali metal fluorides is a persistent challenge. Now this has been achieved by...

We are introducing OpenAI o1, a new large language model trained with reinforcement learning to perform complex reasoning. o1 thinks before it answers—it can produce a long internal chain of thought b...

Chemistry that can break carbon–fluorine bonds in persistent molecules called PFAS could help to clean up the environment. Testing in real-world settings must come next.