Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧 @bluebuleta.bsky.social · 08/06/2026🧵 Happy to share that the final version of our study is finally out in @natcomms.nature.com today: www.nature.com/articles/s41... What started as an unexpected observation—that SETDB1 depletion accelerates X chromosome silencing—led us to uncover a role for SETDB1 in regulating Xist transcription.nature.comSETDB1 and HUSH modulate Xist RNA levels during establishment of X chromosome inactivation - Nature CommunicationsRegulation of X chromosome inactivation in mammals requires precise control of the levels of the non-coding RNA Xist. Almeida et al. describe an autoregulatory mechanism in which nascent Xist transcri... 1198
Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧 @bluebuleta.bsky.social · 27/03/2026Do you want to move to Oxford and join our lab? There is a computational biologist position open atm to develop and implement tools to analyse TE expression in single cell long read data and more. Apply! #TEsky #UniversityofOxford #postdoc 01218
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Susan Gasser @susanmgasser.bsky.social · 11/02/2026Let’s celebrate women and girls in scientific research! Often underestimated, women drive research in biomedical sciences both intellectually and at the bench. Research should be a “gender-blind” endeavor, but rarely is. Stop bigotry ! Stop unconscious bias ! Go women & girls! 07230
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Ben Carty @bencarty.bsky.social · 27/11/2025Very proud to have our latest work now online in @natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4 www.nature.com/articles/s41...nature.comHeterochromatin boundaries maintain centromere position, size and number - Nature Structural & Molecular BiologyCarty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres. 25216
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Biochemical Society @biochemsoc.bsky.social · 26/06/2025Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2... 02211
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Matt Higgins @parasitematt.bsky.social · 25/02/2025A brilliant, kind, funny colleague gone too soon. We will miss you Bela. www.merton.ox.ac.uk/news/remembe...merton.ox.ac.ukRemembering Professor Béla Novák 1956 - 2025With great sadness, we announce the loss of Professor Béla Novák. 0208
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Izzy Jayasinghe @ijayas.bsky.social · 01/12/2024Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.cell.comClosing the scissor-shaped curve: Strategies to promote gender equality in academiaGender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reac... 12314125
Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧Johanna Joyce @johannajoyce.bsky.social · 25/11/2024Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/ 351190595