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Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧

@bluebuleta.bsky.social
309 followers 338 following 8 posts

Scientist interested in heterochromatin formation and transcription regulation, studying transposons in @rberrens.bsky.social lab @uniofoxford Former Brockdorff lab member.

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Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧 @bluebuleta.bsky.social · 17/06/2026
Congrats @flavia-con.bsky.social
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Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧 @bluebuleta.bsky.social · 08/06/2026
🧵 Happy to share that the final version of our study is finally out in @natcomms.nature.com today: www.nature.com/articles/s41... What started as an unexpected observation—that SETDB1 depletion accelerates X chromosome silencing—led us to uncover a role for SETDB1 in regulating Xist transcription.
nature.com
SETDB1 and HUSH modulate Xist RNA levels during establishment of X chromosome inactivation - Nature Communications
Regulation of X chromosome inactivation in mammals requires precise control of the levels of the non-coding RNA Xist. Almeida et al. describe an autoregulatory mechanism in which nascent Xist transcri...
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Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧 @bluebuleta.bsky.social · 27/03/2026
Do you want to move to Oxford and join our lab? There is a computational biologist position open atm to develop and implement tools to analyse TE expression in single cell long read data and more. Apply! #TEsky #UniversityofOxford #postdoc
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Susan Gasser @susanmgasser.bsky.social · 11/02/2026
Let’s celebrate women and girls in scientific research! Often underestimated, women drive research in biomedical sciences both intellectually and at the bench. Research should be a “gender-blind” endeavor, but rarely is. Stop bigotry ! Stop unconscious bias ! Go women & girls!
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Ben Carty @bencarty.bsky.social · 27/11/2025
Very proud to have our latest work now online in @natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4 www.nature.com/articles/s41...
nature.com
Heterochromatin boundaries maintain centromere position, size and number - Nature Structural & Molecular Biology
Carty et al. identify the H3K9 methyltransferases that restrict the size and position of the centromere protein A chromatin domain, maintaining functional centromeres.
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Biochemical Society @biochemsoc.bsky.social · 26/06/2025
Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...
Transcription and Chromatin UK
Manchester, UK
17-19 September 2025
Earlybird deadline: 17 July 2025
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Matt Higgins @parasitematt.bsky.social · 25/02/2025
A brilliant, kind, funny colleague gone too soon. We will miss you Bela. www.merton.ox.ac.uk/news/remembe...
merton.ox.ac.uk
Remembering Professor Béla Novák 1956 - 2025
With great sadness, we announce the loss of Professor Béla Novák.
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Izzy Jayasinghe @ijayas.bsky.social · 01/12/2024
Reading the paper in Cell about how to close the scissor plots in gender representation at senior academic positions, I feel just a touch of pessimism. Having reached a level of seniority (middle management) I didn’t think I ever would, I read these great ideas wanting more, much more /1.
cell.com
Closing the scissor-shaped curve: Strategies to promote gender equality in academia
Gender inequality in STEM fields remains pervasive and undermines the ability for talented individuals to excel. Despite advances, women still encounter obstacles in pursuing academic careers and reac...
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Reposted by Mafalda Almeida 🇵🇹 🇪🇺 🇬🇧
Johanna Joyce @johannajoyce.bsky.social · 25/11/2024
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/
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