iiinova — where your digital self keeps evolving

biomatik.bsky.social @biomatik.bsky.social · 08/09/2025

Congratulations to Xi Qiao & the Ventelä team! They discovered that in head & neck cancer, they found that tumors with high LIMA1-alpha expression respond poorly to surgery and promote metastasis. This biomarker may guide more personalized cancer treatments. 🔗 doi.org/10.1038/s443... #Oncology

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biomatik.bsky.social @biomatik.bsky.social · 01/09/2025

Applause to Amir Namvar Vansofla and the Shahmaleki Lab! Shigella infections kill hundreds of thousands yearly. This team designed a vaccine with multiple epitopes that protected mice from diverse Shigella strains. A big leap for global health. 🔗 doi.org/10.1016/j.ji... #GlobalHealth #Vaccine

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biomatik.bsky.social @biomatik.bsky.social · 25/08/2025

Bravo to Alexander Fenton & Jean Chung! They discovered that Bruton's tyrosine kinase (Btk) assembles on membranes via weak proline-rich region (PRR)–SH3 interactions, enabling phase separation. Btk is a key player in B-cell development and a target in leukemia therapy. 🔗 buff.ly/KlAKcub #Leukemia

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Reposted by @biomatik.bsky.social

David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 19/08/2025

Hey everybody! @drjuliawester.bsky.social and I have a new paper! We surveyed over 800 scientists, science communicators, and science educators who use social media. Conclusion: Scientists no longer find Twitter useful or pleasant, and many have switched to Bluesky! 🧪🌎🦑 doi.org/10.1093/icb/...

doi.org

Scientists no Longer Find Twitter Professionally Useful, and have Switched to Bluesky

Synopsis. Social media has become widely used by the scientific community for a variety of professional uses, including networking and public outreach. For

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biomatik.bsky.social @biomatik.bsky.social · 11/08/2025

Nicholas Vitari & team reveal that short-term morphine disrupts the gut microbiome & triggers immune complement activation. This suggests opioids may suppress homeostasis via host-microbe interactions—critical for chronic pain patients. 🔗 buff.ly/xeGEH8Q #Immunology #Microbiota

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biomatik.bsky.social @biomatik.bsky.social · 08/08/2025

Congratulations to Antonius Chrisnandy from The Lutolf Lab who showed that intestinal stem cells make their own ECM niche, enabling organoid growth without animal-derived laminin. A big step toward defined, scalable culture systems. 🔗 doi.org/10.1016/j.de... #StemCells #OrganoidResearch

doi.org

An extracellular matrix niche secreted by epithelial cells drives intestinal organoid formation

Intestinal organoids have become an important model system in basic and translational research, but their culture typically relies on an ill-defined l…

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biomatik.bsky.social @biomatik.bsky.social · 06/08/2025

Many congratulations to Samrin Habbani and Sayeh Dowlatshahi from the Mohammed lab on another awesome discovery! They identified protein biomarkers for early cervical cancer detection. This could improve screening in underserved areas. 🔗https://buff.ly/YS59dny #Cancer #Diagnostics #GlobalHealth

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biomatik.bsky.social @biomatik.bsky.social · 05/08/2025

Many congratulations to Saranya Reghupaty and Laetitia Voilquin-Coassolo from the Svensson team on another awesome discovery! They found Ism1 loss triggers insulin resistance. This could point to new metabolic disease treatments. 🔗https://buff.ly/NTGFbpY #Metabolism #Diabetes

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biomatik.bsky.social @biomatik.bsky.social · 04/08/2025

Congrats to Serena Muratcioglu from the Kuriyan Lab! They found that TEL-ABL fusion proteins drive resistance to asciminib by forming oligomers. These insights into fusion oncoproteins and drug-resistant leukemias. 🔗 doi.org/10.1126/scis... #Leukemia #CancerSignaling

doi.org

Autophosphorylation of oncoprotein TEL-ABL in myeloid and lymphoid cells confers resistance to the allosteric ABL inhibitor asciminib

Oligomerization renders the oncoprotein TEL-ABL insensitive to the ABL inhibitor asciminib.

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biomatik.bsky.social @biomatik.bsky.social · 01/08/2025

It's maybe not so surprising to anyone familiar with inflammatory immune responses that immunology and oncology are so tightly linked

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biomatik.bsky.social @biomatik.bsky.social · 01/08/2025

I didn't normally use twitter until I started managing Biomatik's social media What stood out most that there's so many more antivaxxers than I thought

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Reposted by @biomatik.bsky.social

Princess Vimentin PhD | Cancer Biologist @princess-vimentin.bsky.social · 31/07/2025

OMFG THIS IS GOOD NEWS! Looks like our senators are starting to understand the potential impacts of the proposed budget cuts. There was bipartisan support for a $400 mil INCREASE in the NIH budget, including preserving all 27 institutes within the NIH. 🧪🔗 www.science.org/content/arti...

science.org

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency

Republicans on spending committee push back against proposed reorganization and overhead cuts

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biomatik.bsky.social @biomatik.bsky.social · 01/08/2025

This is amazing work- enantiomer selection for proteins opens up tons of new biosynthesis options long term

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Reposted by @biomatik.bsky.social

Nature Portfolio @natureportfolio.nature.com · 01/08/2025

A technology feature in Nature describes how enzyme-based techniques and refinements in organic chemistry are easing the generation of extended DNA sequences. 🧬 🧪

go.nature.com

Made-to-order DNA goes big: new tech doubles size of custom genetic sequences

Enzyme-based techniques and refinements in organic chemistry ease the generation of extended DNA sequences.

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biomatik.bsky.social @biomatik.bsky.social · 28/07/2025

Many congratulations to Jessica Regan and Christian DeJarnette from the Palmer lab on another awesome discovery! They found PanK is a key vulnerability in cancer cells. This could spark new selective cancer therapies. 🔗https://doi.org/10.1016/j.chembiol.2025.04.007 #CancerTherapy

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biomatik.bsky.social @biomatik.bsky.social · 24/07/2025

Many congratulations to Luis Ontiveros-Padilla and Dylan Hendy from the @kristy-ainslie-lab.bsky.social on another awesome discovery! They developed a nanocomplex intranasal flu vaccine effective across strains. This could help create a universal, needle-free flu shot. 🔗 doi.org/10.1016/j.jc...

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biomatik.bsky.social @biomatik.bsky.social · 20/07/2025

How writing funding applications be rn

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biomatik.bsky.social @biomatik.bsky.social · 19/07/2025

We're kind of living at the beginning of a disaster movie where everyone ignores the scientist in the room, except there are thousands of scientists

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Reposted by @biomatik.bsky.social

Saganism @sagan.bsky.social · 19/07/2025

We've arranged a society based on science and technology, in which nobody understands anything about science and technology. And this combustible mixture of ignorance and power, sooner or later, is going to blow up in our faces. ~ Carl Sagan

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biomatik.bsky.social @biomatik.bsky.social · 19/07/2025

Agree here, the whole point of a lot of science is to look for data that we don't have already, while ML models specifically require tons of data in the first place. AI could help us produce predictions on breadth, but not in depth of most scientific knowledge

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biomatik.bsky.social @biomatik.bsky.social · 19/07/2025

The problem is that my anxiety can't distinguish between having to use the invention of a Maori prof and a tiger

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biomatik.bsky.social @biomatik.bsky.social · 19/07/2025

Many congratulations to Yongqiang Chen and Yi Duan from the Schnabl team on another awesome discovery! They showed targeting bacterial KpsM reduces alcohol-related liver damage. This could advance microbiome-based therapies for liver disease. 🔗 doi.org/10.1016/j.ch... #Microbiome

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biomatik.bsky.social @biomatik.bsky.social · 17/07/2025

Many congratulations to Duy Phuong Hua and Jacob Kinnun from the Post lab on another awesome discovery! They found Syk kinase acts as a phospho-sensor via an electrostatic network. This could lead to protein-based biosensor designs. 🔗https://doi.org/10.1073/pnas.2421663122 #Science

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biomatik.bsky.social @biomatik.bsky.social · 14/07/2025

Many congratulations to Bok-Soon Lee and Yea-In Park from the Kim lab on another awesome discovery! They found cholesterol enzymes DHCR7/DHCR24 drive colon cancer by generating ROS and activating JNK. This could open new doors for targeting cancer metabolism. 🔗 doi.org/10.1016/j.ca... #Research

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biomatik.bsky.social @biomatik.bsky.social · 13/07/2025

What's your labs funniest superstition?

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biomatik.bsky.social @biomatik.bsky.social · 13/07/2025

I feel like a lot of researchers will relate to this 1/2

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