White House officials clashed in the Oval Office over whether President Donald Trump should take a larger knife to the country's largest medical research agency.According to reporting by The Washingto...

Nature Immunology - Sabatino and colleagues examine expanded CD8+ T cell clonotypes from a small cohort of multiple sclerosis patients. They identified several cognate peptide epitopes that derive...

Nature Immunology - Impairing FRC conduits

Diet-induced obesity (DIO) promotes the accumulation of stromal cells with senescent characteristics in the adipose tissue (AT). Selectively clearing these cells—either through chemical senolytics or ...

Regeneron's chief scientist, George Yancopoulos, has some thoughts about the use of AI in medicine.

Former Intellia scientist John Finn reflects on gene editing's evolution and the closure of Tome Biosciences, highlighting the industry's focus on tools over medicines.

Exclusive: Arena Bioworks, the buzzy research institute that launched with $500 million to support a decade of scientific R&D, is abruptly shutting down, STAT has learned.

Novo Nordisk is ending all work in cell therapy, including a Type 1 diabetes program, amid CEO Maziar Mike Doustdar's reorganization. | Novo Nordisk is ending all work in cell therapy, including a Typ...

Takeda's decision is another blow to a cell therapy industry that has fallen out of favor.

Eli Lilly has halted a study of an experimental drug, designed to prevent obesity patients from losing too much muscle, due to strategic business reasons, according to a U.S. registry of clinical trials.

OPINION: From gene therapies to cancer breakthroughs, California has been the driving force behind America’s biotechnology industry. But today, that edge is slipping.

Vertex is trimming its Rhode Island footprint on the back of a scrapped “cells plus device” program in diabetes, leaving 125 staffers out of a job. | The company is merging its three buildings at its ...

A study shows levels of the amino acid taurine rise rather than fall over time, confounding the goal of dietary supplements popular in anti-aging circles.

Single-cell morphologies reveal functional subtypes of senescence.

The National Institutes of Health is making a major change to how grant recipients can use their funds. | The National Institutes of Health is making a major change to how grant recipients can use the...

An open question in epigenetics is if 5-formylcytosine (5fC) is merely a byproduct of active demethylation or an instructive mark that regulates gene expression on its own. This work demonstrates 5fC ...

Drugmakers — major beneficiaries of NIH-backed university research — have been largely silence on the Trump administration's cuts to agency research payments.

Sam Altman-backed Retro Biosciences is raising $1 billion to develop drugs that extend human lifespan by 10 years, the FT reports.

Beta Bionics has set the terms for its plan to go public, with a goal of raising at least $114 million to support its artificial pancreas system for people with Type 1 diabetes. | The company is set t...

Fraud in research needs to end.

Sana Biotechnology has shared early data for its investigational allogeneic cell therapy being studied in one patient with type 1 diabetes, sending the company’s share price up by about 200%. | Sana B...

The company said Monday that fosigotifator failed to outperform placebo in slowing the neurodegenerative disease, but is testing it further and for other conditions.

The classical musician, who performed with George Harrison and Van Morrison, died in a San Francisco hospital on Sunday

Decision follows observations of liver transaminitis without clinically significant symptoms in some subjects on azelaprag Company will evaluate data from...