iiinova — where your digital self keeps evolving

Bertolin Lab

@bertolinlab.bsky.social

259 followers 374 following 3 posts

www.dundeegenomeintegrity.org www.dundeegenomeintegrity.org/resea… Understanding genomic stability and human disease through a DNA replication lens| Wellcome-funded Group Leader| Former Diffley postdoc, Crick

Posts Replies Media

Bertolin Lab @bertolinlab.bsky.social · 18/02/2026

www.sciencedirect.com/science/arti...

sciencedirect.com

The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks

Understanding how DNA replication forks stall and restart and how the DNA replication checkpoint prevents irreversible fork collapse in molecular deta…

041

Bertolin Lab @bertolinlab.bsky.social · 18/02/2026

www.sciencedirect.com/science/arti...

sciencedirect.com

The DNA replication checkpoint prevents PCNA/RFC depletion to protect forks from HLTF-induced collapse in human cells

The DNA replication checkpoint is crucial for maintaining genome stability after genotoxic stress; without it, stalled DNA replication forks cannot re…

010

Bertolin Lab @bertolinlab.bsky.social · 18/02/2026

To kickstart this new Bluesky account: We're hiring! The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab. Details in the flyer — get in touch! 👇

23330