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Benoit Pugin

@benoitpugin.bsky.social
23 followers 68 following 4 posts

Exploring gut microbiota biochemistry

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Benoit Pugin @benoitpugin.bsky.social · 26/05/2025
Interestingly, we previously showed that L. eligens is an important contributor to gut ILA. Taken together, this could explain the reduction of IPA in diseases associated with gut inflammation doi.org/10.1080/1949...
doi.org
Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionate
Tryptophan-derived indoles produced by the gut microbiota, particularly indole-3-propionate (IPA), are key compounds associated with gastrointestinal balance and overall health. Reduced levels of I...
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Benoit Pugin @benoitpugin.bsky.social · 26/05/2025
We provide a tolerance profile of gut microbes to oxidative stress and reveal previously overlooked sensitive taxa: L. eligens and F. saccharivorans doi.org/10.1093/fems...
doi.org
Deciphering oxidative stress responses in human gut microbes and fecal microbiota: a cultivation-based approach
This study maps how gut microbes respond to oxidative stress, identifies vulnerable and resilient species, and introduces a lab-based system to track chang
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Benoit Pugin @benoitpugin.bsky.social · 10/05/2025
Impressive and crucial work !! We thank you !
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Benoit Pugin @benoitpugin.bsky.social · 08/05/2025
We identified new gut bacteria producing ILA and IPA, namely Lachnospira eligens and Enterocloster aldenensis. 🙌🥳 We also highlight the importance of cross-feeding and dietary fibers. Huge thanks Janina Zünd and to all co-authors #gut #microbiome #fibers #prebiotics #indoles doi.org/10.1080/1949...
doi.org
Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionate
Tryptophan-derived indoles produced by the gut microbiota, particularly indole-3-propionate (IPA), are key compounds associated with gastrointestinal balance and overall health. Reduced levels of I...
041