A new study published in Communications Biology shows how an injection of the psychedelic compound 5-MeO-DMT induces a dissociated brain state in mice, combining elements of sleep and wakefulness.

Administration of 5-MeO-DMT produces a dissociated brain state in mice, characterized by global slow-wave activity alongside behavioral wakefulness and marked pupil dilation.

Psychedelics lead to profound changes in subjective experience and behaviour, which are typically conceptualised in psychological terms rather than corresponding to an altered brain state or a distinc...

Hibernation allows many animals to time-travel from difficult times to plenty. Could humans learn how to do it too?

Vigilance states – waking, slow-wave sleep (SWS) and paradoxical sleep, are thought to be controlled by several cortical and subcortical neuromodulatory circuits, among which the serotonergic (5-HT) s...