The cryo-electron microscopy structure of the bridge-like lipid-transfer protein VPS13A in complex with the scramblase XK—coupled with molecular dynamics simulations—suggests that VPS13A-transported l...

Membranes are heterogeneous 2D mixtures of integral membrane proteins and lipids. The lipid environment and individual lipid molecules are increasingly being shown to affect the structure, dynamics, a...

AbstractSummary. Lipid–protein interactions play essential roles in cellular signaling and membrane dynamics, yet their systematic characterization has lon

A chemodiverse library of new semi-synthetic antimicrobial peptides is reported herein. The polymyxin B nonapeptide (PMBN) holds promise as a developmental platform to access potent antimicrobial lipo...