iiinova — where your digital self keeps evolving

BASE mRNA Facility @basemrna.bsky.social · 26/02/2025

🔬 Ever wondered what mRNA-LNPs look like? Thanks to the Wolfram Group, we have this stunning image of BASE-produced eGFP mRNA encapsulated in LNPs! We’re proud to support researchers with high-quality #mRNA and #LNP, helping drive innovation from the lab to real-world applications.

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BASE mRNA Facility @basemrna.bsky.social · 11/02/2025

We are looking for a Software Engineer who will lead the development of software platform for the design of #mRNA medicines. The role will include developing, implementing, and maintaining mRNA design software to industry standards. www.linkedin.com/jobs/view/41...

linkedin.com

The University of Queensland hiring Software Developer – mRNA design in St Lucia, Queensland, Australia | LinkedIn

Posted 1:56:31 PM. BASE Facility at Australian Institute for Bioengineering and Nanotechnology (AIBN)Full-time (100%),…See this and similar jobs on LinkedIn.

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BASE mRNA Facility @basemrna.bsky.social · 15/01/2025

We look forward to working with the Vaxxas team to deliver #mRNA vaccines using the microarray patch!

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Reposted by BASE mRNA Facility

Seth Cheetham @sethcheetham.bsky.social · 13/01/2025

#mRNA meets cell therapies! It was great to collaborate with Fernando Guimaraes's team to develop mRNA CARs and delivered them to NK cells. NKs transfected with EphA2 CAR mRNA elicited a strong anti-tumour response in animal sarcoma models. onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR

Human NK cells can be efficiently transfected with mRNA to safely express an EphA2-CAR without genomic alterations. EphA2-targeted CAR-NK cells exhibit enhanced cytotoxicity against paediatric sarco...

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BASE mRNA Facility @basemrna.bsky.social · 09/01/2025

We’re excited to announce that we’re back in action and ready to help you achieve your #mRNA goals in 2025. Our team is re-energised and eager to continue providing the reliable, high-quality mRNA solutions. Reach out to us to discuss your project need! 🧬 ✉️ base@uq.edu.au

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Reposted by BASE mRNA Facility

Seth Cheetham @sethcheetham.bsky.social · 09/12/2024

Earlier this year I had the opportunity to present a TEDx talk on the transformative potential of personalised #mRNA vaccines for cancer. The recording is out now: www.youtube.com/watch?v=BnSO... #RNAsky #RNAtx @basemrna.bsky.social

youtube.com

How personalized mRNA vaccines could revolutionize cancer treatment | Seth Cheetham | TEDxUQ

YouTube video by TEDx Talks

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BASE mRNA Facility @basemrna.bsky.social · 05/12/2024

BASE team took some time to celebrate the progress we’ve achieved this year. 🎄 From a delicious team lunch to an epic round of laser tag! 💥🔫 it was a fantastic way to bond, recharge, and have fun. A huge shoutout to our amazing team—your hard work and dedication make all the difference.

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Reposted by BASE mRNA Facility

Seth Cheetham @sethcheetham.bsky.social · 04/12/2024

There are more ways to design an mRNA than atoms in the universe, so how do you choose the best one? Our new @basemrna.bsky.social software, mRNArchitect enables you to tune expression, stability, reactogenicity and synthesisability to design more potent #mRNA drugs. www.biorxiv.org/content/10.1...

biorxiv.org

mRNArchitect: optimized design of mRNA sequences

Summary: mRNA design is the critical first step in the development of a new vaccine or therapy. The mRNA primary sequence is assembled from multiple elements, including the coding sequence of the targ...

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BASE mRNA Facility @basemrna.bsky.social · 05/12/2024

Simply input your coding sequence of interest, and mRNArchitect will provide multiple candidate mRNA sequences, each accompanied by comprehensive statistics for evaluation. At BASE, we have successfully used mRNArchitect to design hundreds of mRNAs for diverse applications. 🧬

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BASE mRNA Facility @basemrna.bsky.social · 05/12/2024

We are excited to introduce #mRNArchitect - a software toolkit for designing and optimising mRNA sequences. basefacility.org.au/software/ This freely available software enables users to generate mRNA candidates optimised for expression, stability& immunogenicity.

basefacility.org.au

Software - BASE mRNA facility

mRNA design software - mRNArchitect is a software toolkit to design, build and optimise mRNA vaccines and therapies.

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Reposted by BASE mRNA Facility

Seth Cheetham @sethcheetham.bsky.social · 25/11/2024

I made a starter pack for interesting people in the mRNA vaccines and therapeutics space. Message me if you want to be added. #RNAsky go.bsky.app/VSHfBce

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BASE mRNA Facility @basemrna.bsky.social · 25/11/2024

We are #hiring! We're looking for an mRNA Production Scientist, a Software Developer, and a Bioinformatician. Join our mRNA Production and mRNA Design teams as we push the boundaries of mRNA innovation! 🧬 www.linkedin.com/posts/base-f...

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Reposted by BASE mRNA Facility

Seth Cheetham @sethcheetham.bsky.social · 19/11/2024

We're building Australia's first centre for the designing and manufacturing personalised cancer vaccines at the BASE mRNA facility. On the PhaseIII podcast I discuss the transformative potential of mRNA for cancer and our efforts to bring this tech to patients. podcasts.apple.com/au/podcast/v...

podcasts.apple.com

VAXXED: Game on, with BASE and WEHI

Podcast Episode · Phase III · 19/11/2024 · 26m

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