Sign in

Matthijs Baars

@baarsmatthijs.bsky.social
36 followers 210 following 0 posts
PostsRepliesMedia
Reposted by Matthijs Baars
Marvin Tanenbaum @marvintanenbaum.bsky.social · 12/02/2026
Out now in Cell Systems: We develop a technique to visualize influenza A virus in live cells with single viral RNA resolution. Combined with precise readouts of viral transcription, we map the whole influenza A viral life cycle and identify key bottlenecks in infection. www.cell.com/cell-systems...
cell.com
Live-cell single-vRNP imaging identifies viral gene expression signatures that shape influenza infection heterogeneity
In this study, an imaging technology, “VISUN,” is developed that allows live-cell visualization of unmodified influenza virus during infection with single-vRNP resolution. Combining VISUN with multipl...
14610
Reposted by Matthijs Baars
Marvin Tanenbaum @marvintanenbaum.bsky.social · 21/01/2025
Our new paper is out: "Mapping the complete influenza A virus infection cycle through single vRNP imaging". Combining newly-developed single-molecule imaging approaches with in situ viral transcriptomics, we identify numerous non-canonical infection pathways. www.biorxiv.org/content/10.1...
biorxiv.org
Mapping the complete influenza A virus infection cycle through single vRNP imaging
Cell-to-cell heterogeneity is a common feature of viral infection that can generate enormous complexity, complicating understanding of infection progression and interpretation of differences between v...
13917