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Atherton Lab KCL

@athertonlabkcl.bsky.social
234 followers 547 following 8 posts

Research group at KCL using cryo-EM and cryo-ET to investigate all things around the cytoskeleton and associated proteins

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Atherton Lab KCL @athertonlabkcl.bsky.social · 10/08/2026
Over-the-moon that our structural #cryo-em work on the #drebrin #F-actin interaction has now been published in full at #NatureCommunications. Congratulations to Weilong, Lee-Ya and the rest of the team in London and Hamburg who worked on this :) www.nature.com/articles/s41...
nature.com
Structural mechanisms of drebrin-mediated F-actin network modulation - Nature Communications
Drebrin regulates crucial cellular processes through its F-actin binding and regulating functions. Here, the authors report cryo-EM structures of drebrin’s actin-binding domains complexed with F-actin...
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Atherton Lab KCL @athertonlabkcl.bsky.social · 03/02/2026
Hi all- we are searching for a new manager/operator to run and develop KCL's Cryo-EM Structural Discovery Facility: a JEOL cryoARM200 + k3 and sample preparation equipment. This 200kV set up recently achieved a 1.2 Å apoferritin! www.biorxiv.org/content/10.6... www.kcl.ac.uk/jobs/137165-...
kcl.ac.uk
Cryo-EM Facility Manager | King's College London
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Atherton Lab KCL @athertonlabkcl.bsky.social · 03/12/2025
New #cryo-EM #preprint- 'Structural mechanisms of drebrin-mediated F-actin network modulation'. Weilong impressively classified out two small #actin binding domains competing for the same surface on #F-actin, one of which also exists in two conformations! #drebrin www.biorxiv.org/content/10.6...
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Atherton Lab KCL @athertonlabkcl.bsky.social · 07/11/2025
Post-doc position alert! We will use #cryo-EM to decipher how a set of actin-binding proteins organises the #cytoskeleton, including during #cancer and #viral pathogenic processes. #KCL has access to; Krios + K3 cryoARM200 + K3 FIB-SEM Cryo-CLEM www.timeshighereducation.com/unijobs/list...
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Reposted by Atherton Lab KCL
Roberto A. Steiner @steinerlab.bsky.social · 06/07/2025
🧪 We have a new publication out in @NatureComms. 🧪Great collaborative work involving @KclRandallMol, @dsb_unipd, @PhD_DSB_UniPD, @cnr_scitec, @humantechnopole. Here's the link www.nature.com/articles/s41...
nature.com
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail - Nature Communications
Kinesin-1 utilizes ATP-driven conformational changes to transport vital intracellular cargoes along microtubules. The authors use cryo-EM to reveal a missing structural transition state of the kinesin...
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Atherton Lab KCL @athertonlabkcl.bsky.social · 07/07/2025
Computational structural biologist post going at #KCL- together with KCL structural biologists, they'll work on enhancing #cryo-EM image processing and structural biology computing capabilities at KCL :) www.kcl.ac.uk/jobs/118906-...
kcl.ac.uk
Computational Structural Biologist
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Atherton Lab KCL @athertonlabkcl.bsky.social · 07/07/2025
Excited to see our @natcomms.nature.com paper out! #Cryo-EM reveals a #microtubule stimulated ADP-release transition state of #kinesin 1. The auto-inhibitory tail has no affect on motor domain conformations. Focussed subunit processing helps! #cryoEM #microtubules www.nature.com/articles/s41...
nature.com
Microtubule association induces a Mg-free apo-like ADP pre-release conformation in kinesin-1 that is unaffected by its autoinhibitory tail - Nature Communications
Kinesin-1 utilizes ATP-driven conformational changes to transport vital intracellular cargoes along microtubules. The authors use cryo-EM to reveal a missing structural transition state of the kinesin...
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Atherton Lab KCL @athertonlabkcl.bsky.social · 14/05/2025
There's a post-doc position going in our group based at the Randall Centre, KCL, UK. The project aims to determine how viruses manipulate host cell cytoskeletons to enhance their replicative capabilities, using cryo-EM/cryo-ET/FIB-SEM. Info/apply: my.corehr.com/pls/coreport...
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Reposted by Atherton Lab KCL
Atherton Lab KCL @athertonlabkcl.bsky.social · 12/02/2025
Hi all- we are searching for a new manager/operator for KCL's Cryo-EM Structural Discovery Facility: a JEOL cryoARM200 + k3 and sample preparation equipment. It's producing excellent high-resolution data using serialEM and Gatan Latitude (EPU-like)! Apply below! www.kcl.ac.uk/jobs/107305-...
kcl.ac.uk
Cryo Electron Microscopy Facility Manager
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Atherton Lab KCL @athertonlabkcl.bsky.social · 12/02/2025
Hi all- we are searching for a new manager/operator for KCL's Cryo-EM Structural Discovery Facility: a JEOL cryoARM200 + k3 and sample preparation equipment. It's producing excellent high-resolution data using serialEM and Gatan Latitude (EPU-like)! Apply below! www.kcl.ac.uk/jobs/107305-...
kcl.ac.uk
Cryo Electron Microscopy Facility Manager
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