Why are some neurons hit so early in Alzheimer’s disease? Our new study suggests that exceptionally high reelin levels may help explain the onset of the disease.
journals.plos.org/ploscompbiol...
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High reelin expression may explain why a subgroup of entorhinal cortex neurons functions as an initial nucleation site of Alzheimer’s disease
Author summary Why the entorhinal cortex, located adjacent to the hippocampus in the medial temporal lobe, is a major cradle of the onset of Alzheimer’s disease still eludes us. In contrast to most ot...
