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Anupama Jha, PhD

@anupamajha.bsky.social
59 followers 68 following 0 posts

Assistant Professor of Genetics at Yale. Pronouns: she/her

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Reposted by Anupama Jha, PhD
wnoble.bsky.social @wnoble.bsky.social · 21/12/2024
HiCFoundation is a Swiss army knife for Hi-C data. Any task that takes Hi-C as input will benefit from our pre-trained model. You can do resolution enhancement, reproducibility analysis, loop calling, prediction of epigenomic profiles, or single-cell Hi-C analysis. tinyurl.com/v3nmp6np
tinyurl.com
A generalizable Hi-C foundation model for chromatin architecture, single-cell and multi-omics analysis across species
Nuclear DNA is organized into a compact three-dimensional (3D) structure that impacts critical cellular processes. High-throughput chromosome conformation capture (Hi-C) is the most widely used method...
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Reposted by Anupama Jha, PhD
wnoble.bsky.social @wnoble.bsky.social · 02/12/2024
How can you transfer peptide IDs between runs and still control your false discovery rate? Till now, the short answer is, you couldn't. Now you can, with PIP-ECHO. www.biorxiv.org/content/10.1...
biorxiv.org
Improved detection of differentially abundant proteins through FDR-control of peptide-identity-propagation
Quantitative analysis of proteomics data frequently employs peptide-identity-propagation (PIP) — also known as match-between-runs (MBR) — to increase the number of peptides quantified in a given LC-MS...
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